ID A0A151LZB1_ALLMI Unreviewed; 668 AA.
AC A0A151LZB1;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE SubName: Full=Melanocyte protein PMEL {ECO:0000313|EMBL:KYO17570.1};
GN Name=PMEL {ECO:0000313|EMBL:KYO17570.1};
GN ORFNames=Y1Q_0020303 {ECO:0000313|EMBL:KYO17570.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO17570.1};
RN [1] {ECO:0000313|EMBL:KYO17570.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO17570.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- SIMILARITY: Belongs to the PMEL/NMB family.
CC {ECO:0000256|ARBA:ARBA00025776}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO17570.1}.
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DR EMBL; AKHW03006970; KYO17570.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A151LZB1; -.
DR STRING; 8496.A0A151LZB1; -.
DR eggNOG; ENOG502QV5K; Eukaryota.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00146; PKD; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR045219; PKAT.
DR InterPro; IPR046846; PKAT_KLD.
DR InterPro; IPR022409; PKD/Chitinase_dom.
DR InterPro; IPR000601; PKD_dom.
DR InterPro; IPR035986; PKD_dom_sf.
DR PANTHER; PTHR11861:SF1; MELANOCYTE PROTEIN PMEL; 1.
DR PANTHER; PTHR11861; MELANOCYTE PROTEIN PMEL 17-RELATED; 1.
DR Pfam; PF20433; PKAT_KLD; 1.
DR Pfam; PF00801; PKD; 1.
DR SMART; SM00089; PKD; 1.
DR SUPFAM; SSF49299; PKD domain; 1.
DR PROSITE; PS50093; PKD; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000050525};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 647..667
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 261..301
FT /note="PKD"
FT /evidence="ECO:0000259|PROSITE:PS50093"
FT REGION 1..40
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 334..419
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 471..494
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 334..375
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 474..494
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 668 AA; 67378 MW; AA9669753C1DDDFC CRC64;
MNEDPRHPGS VLLPLGVRAA SGPGGRNRGS DRGSRQPLGY RSWNSQLYPW GPRGDARQRD
CWRGGDVTFE VTNDAPTMTG AKATFAIALR FPSNQTVLPD GRVVWSRNCT VNGTWVRQGD
AVFPEMLPEG TAGTFPDGQP FPRSAWGGRS KFVYVWWTWG RYWQVVDGPS SQLTVDTAGV
PLGSYSMAVE VYHYRGPRKF VPLGNTASQF SITDQVPFSV DVAQVETAAV AGAEPGVAER
FVRNRAVSFT VRLHDPSGYL TGADVACSWD FGDGSGTLIS RAAQVTHTYL ATGSFTPRVV
LQAAIPLACG GTSPATATAT GPPVQPTGAT AAATIATGGS PGQATVQPPS SAPTAEATGS
PASGATGSPA TASPASGDPA TAAPASGDPA TAAPASDDPA TVSPASGDPA TVAPASEELD
TEPLATAGLA DPDAGTTLPA AATASGLPSM AAAPGSDLAV ASVDPLLPAS TSPAADLPPT
TGSAGPSLPA SVASTSSGTA EVTASTAVPS AAPALVLAKR QAPPNGCVLY RYGTFSTQLD
IVQGIESVEI VQVVPAAGES AVELTVTCQG SLPDEVCTVV MDAACLAPQQ TVCSPVPPAP
ACQLVLHQAF NQSGQYCLNV SLANPSGLAM ASTHVTVGGA DAAGTRVTLL VGLVLVAVAL
GVVGLAYR
//
