ID A0A151M798_ALLMI Unreviewed; 502 AA.
AC A0A151M798;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Apolipoprotein L3 {ECO:0000313|EMBL:KYO20408.1};
GN Name=APOL3 {ECO:0000313|EMBL:KYO20408.1};
GN ORFNames=Y1Q_0006785 {ECO:0000313|EMBL:KYO20408.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO20408.1};
RN [1] {ECO:0000313|EMBL:KYO20408.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO20408.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- SIMILARITY: Belongs to the apolipoprotein L family.
CC {ECO:0000256|ARBA:ARBA00010090}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO20408.1}.
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DR EMBL; AKHW03006430; KYO20408.1; -; Genomic_DNA.
DR RefSeq; XP_019333874.1; XM_019478329.1.
DR AlphaFoldDB; A0A151M798; -.
DR STRING; 8496.A0A151M798; -.
DR GeneID; 106738055; -.
DR KEGG; amj:106738055; -.
DR OrthoDB; 5319909at2759; -.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0006869; P:lipid transport; IEA:InterPro.
DR GO; GO:0042157; P:lipoprotein metabolic process; IEA:InterPro.
DR Gene3D; 3.40.390.10; Collagenase (Catalytic Domain); 1.
DR InterPro; IPR008405; ApoL.
DR InterPro; IPR029463; Lys_MEP.
DR InterPro; IPR024079; MetalloPept_cat_dom_sf.
DR PANTHER; PTHR14096; APOLIPOPROTEIN L; 1.
DR PANTHER; PTHR14096:SF28; PROTEIN CBG02395; 1.
DR Pfam; PF05461; ApoL; 2.
DR Pfam; PF14521; Aspzincin_M35; 1.
DR SMART; SM01351; Aspzincin_M35; 1.
DR SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
PE 3: Inferred from homology;
KW Lipoprotein {ECO:0000313|EMBL:KYO20408.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000050525}.
FT DOMAIN 67..207
FT /note="Lysine-specific metallo-endopeptidase"
FT /evidence="ECO:0000259|SMART:SM01351"
SQ SEQUENCE 502 AA; 54542 MW; A1D333B76F5CD8E1 CRC64;
MSLREAIVCC KVGNERRCCV CNISHDGRGV PLATGKDSIA EAARQSALDV LRDAVKKKDR
VLMETPRDLI SCDSEQPQFW MERYAVLTEQ RVRDLISVLE EAQFMEDPSR EKVLAWVRPK
SGDKTIYLCP LFWEAPSHLE KDSQPGTLIH EASHFLGTCD ITYEPIGIYV CCEGLMVKNS
STDPDSPKFV PLVPAVLSAN NAEYEFERTL RHRGDYAQGR YSCCGEPARS SVCESAVPDE
LLTCSNTWRE LEEMSIGEIL RKELLSARDR LQQHVAALQA IADAVDKVHR GATIASITGG
TVGIAGGITT VVGLCLAPVT FGASLIVSLT GLGVSLAGGL TSAAATTTDV VQSRVKKEEI
NGLLGQCQAE VQLIRECMKT LCEKLQQDSG SYFNPDLLPE IPQVVSVAGR TVLHTVKAVS
VGKLLASAGL IARITAHALT ALTLGLDVFF VAKDSVELHN GAKTELASKI REAVAELERV
IDQVNHVYEV LTGEKPELDP EE
//
