ID A0A151M7C5_ALLMI Unreviewed; 988 AA.
AC A0A151M7C5;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 22-FEB-2023, entry version 15.
DE SubName: Full=Protein FAM13B isoform B {ECO:0000313|EMBL:KYO20340.1};
GN Name=FAM13B {ECO:0000313|EMBL:KYO20340.1};
GN ORFNames=Y1Q_0010865 {ECO:0000313|EMBL:KYO20340.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO20340.1};
RN [1] {ECO:0000313|EMBL:KYO20340.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO20340.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- SIMILARITY: Belongs to the FAM13 family.
CC {ECO:0000256|ARBA:ARBA00007549}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO20340.1}.
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DR EMBL; AKHW03006437; KYO20340.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A151M7C5; -.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd04393; RhoGAP_FAM13A1a; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR039102; FAM13.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR15904; FAM13; 1.
DR PANTHER; PTHR15904:SF16; PROTEIN FAM13B; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000050525}.
FT DOMAIN 103..292
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 318..345
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 404..428
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 559..582
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 615..642
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 691..742
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 878..901
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 318..337
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 410..428
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 562..576
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 625..642
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 703..718
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 988 AA; 112958 MW; 094D242612615AB6 CRC64;
MGSQPSCHTL PELLLPWQSK LGGYAAGALA AKKGAGLSVL QLPISLPYWE KRSQTKYRLT
AEVLIDPLRR DSFDFWLQKD MRKSSSPSLS NCNSVLANKI FGIPLDELQQ EGQPDNEVPF
IVRHVVDYIE EHGGLEQEGL FQVNGNAETV EWLRQRYDNG EDVDLVKEAD VPSAISLLRF
FLQELPEPVI PGSLHIHLMQ LSQDYNNEDE FGRKLRFLLQ QLPPVNYSLL KFLCRFLANV
ASHHEEIWSA SSLAAVFGPD VFHIYTDVED LKEQEIVSRI MAGLLENYYE FFENEEEEFS
STNDLSSITE QINDLLEEEE EDDKLEQSEE LPEDSMEKPD EGPDMVHLGT VESFSESSSV
TASTSILERT IRAAVEQHLF DLQSSIDHDL KNLQQHQLVC NNEAKSVNRE EGSNNQDDVT
KGNDDNSCEN TRDCSEALVC ADLDSEVIQP DSVTEEDDDQ TAGVLLKPCN EDEETDEENN
SERQGCILLD DNDKMSSQLL MDSSSKICDL NANTDSEVSG DGNINVFEEA VGIQAPHLDL
KNISDGDKWE EPFPAFKSWQ EDSESGEAQL SPQAGRMNNH PLEEDCHPVL SHRSLDFGQS
QRFLHDPEML DSSSKALSFA RTRRGSFSSK DDKREDRTPY QLVKKLQKKI RQFEEQFEKE
KNSKPSYSDI AANPKVLKWM TELTKLRKQI KDAKHKSSDG EFIPQTRPRS NTLPKSFGSS
LDHEDEENED EPRVMQKEKK PTKEATLEII LKRLKEKRVE RCLPEDIKKM TKDHLVEEKT
SLQKSLLYYE SQHGRPVTRE ERHIVKPLYD RYRLVKQMLT RASITPILGS PSTKRRGQML
QPIIEGETAH FFEEIKEEEE EGDCLSSDLN EILKTAVQTQ SVSSPVENSE SDVEEGQEKL
TRDLRLSSTR AASMPELLEQ LWKARAEKKK LRKTLREFEE GFYQQNGRNV QKEDRVPMLD
EYREYKKIKA KLRLLEVLIS KQDSSKSI
//
