ID A0A151M7T2_ALLMI Unreviewed; 964 AA.
AC A0A151M7T2;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Fetuin-B isoform A {ECO:0000313|EMBL:KYO20500.1};
GN Name=FETUB-1 {ECO:0000313|EMBL:KYO20500.1};
GN ORFNames=Y1Q_0014848 {ECO:0000313|EMBL:KYO20500.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO20500.1};
RN [1] {ECO:0000313|EMBL:KYO20500.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO20500.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO20500.1}.
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DR EMBL; AKHW03006382; KYO20500.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A151M7T2; -.
DR STRING; 8496.A0A151M7T2; -.
DR eggNOG; ENOG502S28K; Eukaryota.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR GO; GO:0004869; F:cysteine-type endopeptidase inhibitor activity; IEA:InterPro.
DR CDD; cd00042; CY; 5.
DR Gene3D; 3.10.450.10; -; 6.
DR InterPro; IPR000010; Cystatin_dom.
DR InterPro; IPR025760; Cystatin_Fetuin_A.
DR InterPro; IPR025764; Cystatin_Fetuin_B.
DR InterPro; IPR046350; Cystatin_sf.
DR InterPro; IPR001363; Prot_inh_fetuin_CS.
DR PANTHER; PTHR13814; FETUIN; 1.
DR PANTHER; PTHR13814:SF10; FETUIN-B; 1.
DR Pfam; PF00031; Cystatin; 4.
DR SMART; SM00043; CY; 6.
DR SUPFAM; SSF54403; Cystatin/monellin; 6.
DR PROSITE; PS51529; CYSTATIN_FETUIN_A; 2.
DR PROSITE; PS51530; CYSTATIN_FETUIN_B; 2.
DR PROSITE; PS01254; FETUIN_1; 1.
DR PROSITE; PS01255; FETUIN_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000050525};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 240..354
FT /note="Cystatin fetuin-A-type"
FT /evidence="ECO:0000259|PROSITE:PS51529"
FT DOMAIN 365..476
FT /note="Cystatin fetuin-A-type"
FT /evidence="ECO:0000259|PROSITE:PS51529"
FT DOMAIN 569..682
FT /note="Cystatin fetuin-B-type"
FT /evidence="ECO:0000259|PROSITE:PS51530"
FT DOMAIN 693..804
FT /note="Cystatin fetuin-B-type"
FT /evidence="ECO:0000259|PROSITE:PS51530"
FT REGION 816..876
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 816..840
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 841..856
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 964 AA; 106177 MW; F938A38AE470FD63 CRC64;
MVFHDTFQHY EVPCNARIAE KTARLAISYI NEDRTEGYKL SLNRINRVFG SHQGAAGKVY
YLDLDVLETK CYIRSALPWE DCDIRPFVET KVSGTCRAIV HIKPDVSAIT CGYNCSLAPD
AKENITSICP ECLTFITPDS RESMKAVNLT LNKFNKESDE SRYFAAAKVI RALSSTLTQP
GQDYHVEFTI EETDCIKGRD GIGRSCTFKS PETARTGFCV GDVYIKDGAD VEASCELYDP
KGPNDAPQGM RDCDSPEGEE AAAVAVDYIN AHHAHGYKYA LNRIEKLRVL PTGPSSERVI
LELDLLETKC HVLNPLPLEN CTVRELTGHA VEGDCDVKLL RKDGKLSVLA AHCHSSPDSA
EDIIKICPDC ALLIPLNDTQ VVKAVELLLD QYHSTNDVYF TLVEIARAQM QAPNTIIVEF
AISATNCSSK DASEHAEACQ ALSGDQTTFG FCVGSVMHVP NENIHVECEV YAPQPDVVHP
VLAKDTVGLL SVPVHGFSHH NLRHSHSSHF NDSSESNSAE VSVACTLSPK LVVKRTVSEP
EHPGGVLDPL HPGCPGRALC SQAFSTPVKE LQSPFLFPAC NDSAVESAVD VALGQINTGR
TEGYVLRLNR IFSVLEHPQE TSGSVFYLIL DVAETECHVL SRRLWKNCKT RPQHKTVFGQ
CRTTLYINNP KRIAHLHSYE CTLRPVPTRS ILMLCPDCPI FGCPTEPKYL ETAVVSLAKF
NSESTEAHYF SVLNVTKASM QWVVGPAYFV EFTIQETSCS RNESIADISK CKPLPFEKAH
TGFCKGSVVN SQVDHHQFVN IDCEIYEPQV PAIEKQKETD SHKPGHGGDG SHEDPHHPRR
KGAHPHQKHQ HRHKQHEEKH PSPTEAKSPV EYIDGNPVLP EVGMPVPDLP DIHGAPDGEK
ILTEGPGGKL GLIKPKTGPV FLSFPDELSH SDMCPGEPTT SNSFILNLLP RKHIKESPTA
TPLS
//
