ID A0A151MAK9_ALLMI Unreviewed; 967 AA.
AC A0A151MAK9;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE RecName: Full=AT-rich interactive domain-containing protein 3 {ECO:0000256|RuleBase:RU369100};
DE Short=ARID domain-containing protein {ECO:0000256|RuleBase:RU369100};
GN Name=ARID3B {ECO:0000313|EMBL:KYO21531.1};
GN ORFNames=Y1Q_0001712 {ECO:0000313|EMBL:KYO21531.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO21531.1};
RN [1] {ECO:0000313|EMBL:KYO21531.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO21531.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- FUNCTION: Transcription factor. {ECO:0000256|RuleBase:RU369100}.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|RuleBase:RU369100}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU369100}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO21531.1}.
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DR EMBL; AKHW03006295; KYO21531.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A151MAK9; -.
DR STRING; 8496.A0A151MAK9; -.
DR eggNOG; KOG2744; Eukaryota.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd16879; ARID_ARID3B; 1.
DR CDD; cd00276; C2B_Synaptotagmin; 1.
DR Gene3D; 1.10.150.60; ARID DNA-binding domain; 1.
DR Gene3D; 2.60.40.150; C2 domain; 2.
DR InterPro; IPR045147; ARI3A/B/C.
DR InterPro; IPR001606; ARID_dom.
DR InterPro; IPR036431; ARID_dom_sf.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR023334; REKLES_domain.
DR PANTHER; PTHR15348:SF3; AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 3B; 1.
DR PANTHER; PTHR15348; AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN ARID DOMAIN- CONTAINING PROTEIN DEAD RINGER PROTEIN B-CELL REGULATOR OF IGH TRANSCRIPTION BRIGHT; 1.
DR Pfam; PF01388; ARID; 1.
DR Pfam; PF00168; C2; 2.
DR SMART; SM01014; ARID; 1.
DR SMART; SM00501; BRIGHT; 1.
DR SMART; SM00239; C2; 2.
DR SUPFAM; SSF46774; ARID-like; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 2.
DR PROSITE; PS51011; ARID; 1.
DR PROSITE; PS50004; C2; 2.
DR PROSITE; PS51486; REKLES; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU369100};
KW Nucleus {ECO:0000256|RuleBase:RU369100};
KW Reference proteome {ECO:0000313|Proteomes:UP000050525};
KW Transcription {ECO:0000256|RuleBase:RU369100};
KW Transcription regulation {ECO:0000256|RuleBase:RU369100}.
FT DOMAIN 199..291
FT /note="ARID"
FT /evidence="ECO:0000259|PROSITE:PS51011"
FT DOMAIN 396..496
FT /note="REKLES"
FT /evidence="ECO:0000259|PROSITE:PS51486"
FT DOMAIN 671..790
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 821..956
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT REGION 52..181
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 304..332
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 64..90
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 117..132
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 312..332
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 967 AA; 107647 MW; 7EB97F25CC214845 CRC64;
MDSRERQQRQ IREAQMLYTQ QLAAQHAVLA ATSGRASGGS AVGPLARVPP VAGAARAFDQ
SSMNSDPEEE EEEDEEEEDE EEEGGLEGGD LEDGTEMTGK DACSALKFFH SPKVAHHNQR
VASTSNPTPG HQRGQPVKEE QGKDTTKQPY SDSPSGRQPW RLDDQLKQNG NLSWSEEADG
GRGREISRDF AKLYELDSDP ERKEFLDDLF IFMQKRGTPI NRIPIMAKQI LDLYMLYKLV
TEKGGLVEII NKKIWREITK GLNLPTSITS AAFTLRTQYM KYLYAYECEK KSLSSPAELQ
AAIDGNRREG RRPSYSSSLF SYSPSTTGSP SLLSPPKIRF PIIGVTPGSG TSSPRVSPAT
AVRKGDGVPL TVSMPNRIAM PVALANQQAT VAARTATLEQ LRERLESGEP PEKKFSRMTE
EEQRLVQQAL QRNLFSMARQ IPMKIKINGR EDKPDSAAAA AAALNLSPSG IGSINMSVEI
NGTIYAGVLF AQKPDSSVLS AHLQSQINEA EHLQVFLGVG LALLCFSLLL GCAICWRRSR
WHKHNSSKNR VLEQTLVDLR PALPSKTTAV AIQQQNTRIV GEAANDLPGS PGCGSPPNRT
VLSRTSLSSY PFSQALNLPS MLLEGWEHRR NISRDSIFYD EHRPLTSPMQ GACLHQSYTV
PENLSSTGSK PWPQLHFTLL YSQSEATLTV TVIGVSHLPK VSRSSRSSYV KVYLLPRFIE
PQRTAVRRKS LNPEFQEQFQ FGRYSLEELR GFTLRFAVYM KTRSLKDLFI GEVLFPCAQV
TWNPKVSSSY SWELSTTKTK LRKCLSSQDV SSSISSSQPR SMGQLFLLLQ YQALANRIKV
LIRKAENLSR LTRVPGTPDH YIVIHLYHNG KIIDTKETKG IAGYNPVWNT PFLFSIPAGD
IQQQQLSLEF IVMQVRIYTR SCTLGRVLIG PNAPEAGLIH WKEMCSRGQV ESARWHLIQP
DASRLSP
//
