ID A0A151MC57_ALLMI Unreviewed; 820 AA.
AC A0A151MC57;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Transcription factor SOX-6 isoform B {ECO:0000313|EMBL:KYO22082.1};
GN Name=SOX6 {ECO:0000313|EMBL:KYO22082.1};
GN ORFNames=Y1Q_0000693 {ECO:0000313|EMBL:KYO22082.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO22082.1};
RN [1] {ECO:0000313|EMBL:KYO22082.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO22082.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO22082.1}.
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DR EMBL; AKHW03006283; KYO22082.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A151MC57; -.
DR STRING; 8496.A0A151MC57; -.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd22042; HMG-box_EGL13-like; 1.
DR Gene3D; 1.10.30.10; High mobility group box domain; 1.
DR InterPro; IPR009071; HMG_box_dom.
DR InterPro; IPR036910; HMG_box_dom_sf.
DR PANTHER; PTHR45789; FI18025P1; 1.
DR PANTHER; PTHR45789:SF1; TRANSCRIPTION FACTOR SOX-6; 1.
DR Pfam; PF00505; HMG_box; 1.
DR SMART; SM00398; HMG; 1.
DR SUPFAM; SSF47095; HMG-box; 1.
DR PROSITE; PS50118; HMG_BOX_2; 1.
PE 4: Predicted;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00267}; Nucleus {ECO:0000256|PROSITE-ProRule:PRU00267};
KW Reference proteome {ECO:0000313|Proteomes:UP000050525}.
FT DOMAIN 613..681
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DNA_BIND 613..681
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT REGION 44..64
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 370..458
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 494..522
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 745..820
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 213..286
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 48..63
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 370..410
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 423..452
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 745..783
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 790..805
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 820 AA; 91072 MW; 2104431EB4F08320 CRC64;
MPSSSEVLAG VVGESRTEEW KNSHYIRMSS KQATSPFACA ADGEEAMTQD LASRDKEEGN
NDQHATSHLP LHTIMHNNPH SEELPTLVTT IQQDAEWDSV ISAQHRMESE SNKLCSLYSF
RNTSTSPHKP DEGGRDRSEL MTSVNFGTPE RRKGSLADVV DTLKQKKLEE MTRTEQEDSS
CMEKLLSKDW KEKMERLNTS ELLGEIKGTP ESLAEKERQL STMITQLISL REQLLAAHDE
QKKLAASQIE KQRQQMDLAR QQQEQIARQQ QQLLQQQHKI NLLQQQIQQV QGHMPPLMIP
IFPHDQRTLA AAAAAQQGFL FPPGITYKPG DNYPVQFIPS TMAAAAASGL SPLQLQQLYA
AQLASMQVSP GAKMPTTPQP PNTTGALSPT GMKNEKRGTS PVTQVKDEAA QPLNLSARPK
TAEPVKSPTS PTQNLFPASK SSPVNVSNKS GIPSPIGGPL GRGSSLDILS SLNSPALFGD
QDTVMKAIQE ARKMREQIQR EQQQQQQQPP PHTVDGKLPS MNNMGLNNCR NEKERTRFEN
LGPQLTGKPN EDGKLGPGVI DLTRPEDAEG SKAMNGSAAK LQQYYCWPTG GATVAEARVY
RDSRGRASSE PHIKRPMNAF MVWAKDERRK ILQAFPDMHN SNISKILGSR WKSMSNQEKQ
PYYEEQARLS KIHLEKYPNY KYKPRPKRTC IVDGKKLRIG EYKQLMRSRR QEMRQFFTVG
QQPQIPITTG TGVVYPGAIT MATTTPSPQM TSDCSSTSAS PEPSIPVIQS TYGMKTDSGS
LAGNEMINGE DEIEMYEDYE DDPKSDYSSE NEAPEAVSAN
//
