ID A0A151MDU6_ALLMI Unreviewed; 832 AA.
AC A0A151MDU6;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Neural cell adhesion molecule 2 {ECO:0008006|Google:ProtNLM};
GN ORFNames=Y1Q_0003210 {ECO:0000313|EMBL:KYO22706.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO22706.1};
RN [1] {ECO:0000313|EMBL:KYO22706.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO22706.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO22706.1}.
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DR EMBL; AKHW03006231; KYO22706.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A151MDU6; -.
DR eggNOG; KOG3510; Eukaryota.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR CDD; cd00063; FN3; 2.
DR CDD; cd00096; Ig; 1.
DR CDD; cd05866; IgI_1_NCAM-2; 1.
DR CDD; cd05870; IgI_NCAM-2; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 7.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013106; Ig_V-set.
DR InterPro; IPR009138; Neural_cell_adh.
DR PANTHER; PTHR12231; CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN; 1.
DR PANTHER; PTHR12231:SF231; NEURAL CELL ADHESION MOLECULE 2; 1.
DR Pfam; PF00041; fn3; 2.
DR Pfam; PF07679; I-set; 4.
DR Pfam; PF13927; Ig_3; 1.
DR PRINTS; PR01838; NCAMFAMILY.
DR SMART; SM00060; FN3; 2.
DR SMART; SM00409; IG; 5.
DR SMART; SM00408; IGc2; 5.
DR SMART; SM00406; IGv; 3.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 5.
DR PROSITE; PS50853; FN3; 2.
DR PROSITE; PS50835; IG_LIKE; 5.
PE 4: Predicted;
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000050525};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..832
FT /note="Neural cell adhesion molecule 2"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5007585019"
FT TRANSMEM 690..713
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 16..103
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 108..181
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 204..292
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 297..391
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 396..486
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 493..586
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 588..683
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 759..813
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 759..779
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 795..810
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 832 AA; 92490 MW; 827946AA4EF21BD4 CRC64;
MSGFIFNFLK AIKALLQVAI SLSKVELSVG ESKFFTCTAI GEPDSIDWYN PQGEKIVSSQ
RVVVQKEGVR SRLTIYNANV EDAGIYRCQA TDAKGQSQEA TVVLEIYQKL TFRDITSPQE
FRQGEDAEVV CRVTSSPAPV VSWLYRNEEV TTIADNRFAM LANNNLQIIN INKSDEGIYR
CEGRVEARGE IDFRDIIVIV NVPPSITVLQ KSFNATADRG EAITLFCRAT GSPEPEIIWY
RNGKLIEESE KYILKGSHTE LTIKDIKNID AGPYVCEAKN KAGNDKKQTF LQVFVQPQII
QLKNETTFEN GQTTLICEAE GEPIPEITWK RAIDGITFSE GDKSPDGRIE VKGQHGKSSL
HIKDVKLSDS GRYDCEAASR IGGHQKSMFL DIEYAPTFVS NQTMYYSWEG NPINISCEVL
ANPSASIQWR RGKLVLPAKN TTHLKTYSAG RKLILEIAPT SDNDFGRYNC TATNRIGTRY
QEYTLGQADV PSSPYGVKIL ELSQTTAKVS FNKPDSHGGV PIHHYQVDVK EVTSETWKIV
RSHGVQTMVV LSNLEPNTTY EIKVAAVNGK GQGEYSKIEI FQTLPVREPS PPSIHGQPGS
GKSFKLSITK QDDGGAPILE YIVKYRSKDK EDQWLEKKVQ GSRDHIILEH LQWTMGYEVQ
ITAANRLGYS EPTLYEFSMP PKPNIITDTL FNGLGLGAVI GLGVAALLLV LVVTDVSCFF
VRQCGLLMCI TRRICGKKSG SSGKSKELEE GKAAYLKDGS KEPIVEMRTE DERITNHEDG
SPVNEPNETT PLTEPEKLPL KEENGKEALN PETIEIKVTN DIIQSKEDDS KA
//
