ID A0A151MEB2_ALLMI Unreviewed; 422 AA.
AC A0A151MEB2;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 24-JAN-2024, entry version 12.
DE RecName: Full=Lebercilin-like protein {ECO:0000256|ARBA:ARBA00041189};
DE AltName: Full=Leber congenital amaurosis 5-like protein {ECO:0000256|ARBA:ARBA00041402};
GN Name=LCA5L {ECO:0000313|EMBL:KYO22847.1};
GN ORFNames=Y1Q_0003318 {ECO:0000313|EMBL:KYO22847.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO22847.1};
RN [1] {ECO:0000313|EMBL:KYO22847.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO22847.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- SIMILARITY: Belongs to the LCA5 family.
CC {ECO:0000256|ARBA:ARBA00010229}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO22847.1}.
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DR EMBL; AKHW03006231; KYO22847.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A151MEB2; -.
DR STRING; 8496.A0A151MEB2; -.
DR eggNOG; ENOG502QQSE; Eukaryota.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR InterPro; IPR026188; Lebercilin-like.
DR InterPro; IPR028933; Lebercilin_dom.
DR PANTHER; PTHR16650; C21ORF13-RELATED; 1.
DR PANTHER; PTHR16650:SF9; LEBERCILIN-LIKE PROTEIN; 1.
DR Pfam; PF15619; Lebercilin; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000050525}.
FT DOMAIN 1..61
FT /note="Lebercilin"
FT /evidence="ECO:0000259|Pfam:PF15619"
FT REGION 120..157
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 206..266
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 377..422
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 206..243
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 244..266
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 389..422
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 422 AA; 48476 MW; 09FAD2A5B54D9F4C CRC64;
MEASDKKIQG LEKQLKLKNS IFNHQMAAES KKSIAARTIT EALQMEITCL HQKLKERERE
LGIRNIYTNQ MFKSIQDKAD PVPHKKGLIL NKSVQVDKQS FKLRHQKQER EKIAVLLTEE
KRATENTSQN GRAHEAHKDA AHKKEETEPT KKLLKPETSN RTFRVFLREE TQLMEEKIHF
ECMERGKKKK EVQERKADFL KELEKLLNDE QTPSTDDAPK RESNQEKDAV EENEKEERKK
SNQLSDNTAA NKCVTSTQRN RTPTRLKKQY TFTEVIENLH QGIPASGPIS NTGSFRNKPG
RHQCETASKA RTSFGVYEPS FGKCIKARQK ASPAEDGEYT HRTLMERKNT LMKELFGPGS
VLKDNHSNLN TRLLEKEKSM ESERIQDDQR CTISNNPGLQ CGDFKTPPIK SIQTLSSSED
AK
//
