ID A0A151MHR1_ALLMI Unreviewed; 743 AA.
AC A0A151MHR1;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Tudor domain-containing protein 3 {ECO:0000256|ARBA:ARBA00013421};
GN Name=TDRD3 {ECO:0000313|EMBL:KYO24067.1};
GN ORFNames=Y1Q_0004648 {ECO:0000313|EMBL:KYO24067.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO24067.1};
RN [1] {ECO:0000313|EMBL:KYO24067.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO24067.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO24067.1}.
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DR EMBL; AKHW03006155; KYO24067.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A151MHR1; -.
DR STRING; 8496.A0A151MHR1; -.
DR eggNOG; KOG3683; Eukaryota.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR CDD; cd20413; Tudor_TDRD3; 1.
DR CDD; cd14282; UBA_TDRD3; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR Gene3D; 2.40.50.770; RecQ-mediated genome instability protein Rmi1, C-terminal domain; 1.
DR InterPro; IPR042470; RMI1_N_C_sf.
DR InterPro; IPR013894; RMI1_OB.
DR InterPro; IPR002999; Tudor.
DR InterPro; IPR047379; Tudor_TDRD3.
DR InterPro; IPR015940; UBA.
DR InterPro; IPR009060; UBA-like_sf.
DR InterPro; IPR041915; UBA_TDRD3.
DR PANTHER; PTHR13681; SURVIVAL OF MOTOR NEURON-RELATED-SPLICING FACTOR 30-RELATED; 1.
DR PANTHER; PTHR13681:SF24; TUDOR DOMAIN-CONTAINING PROTEIN 3; 1.
DR Pfam; PF08585; RMI1_N_C; 1.
DR Pfam; PF00567; TUDOR; 1.
DR Pfam; PF00627; UBA; 1.
DR SMART; SM01161; DUF1767; 1.
DR SMART; SM00333; TUDOR; 1.
DR SMART; SM00165; UBA; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR SUPFAM; SSF46934; UBA-like; 1.
DR PROSITE; PS50304; TUDOR; 1.
DR PROSITE; PS50030; UBA; 1.
PE 4: Predicted;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000050525}.
FT DOMAIN 280..320
FT /note="UBA"
FT /evidence="ECO:0000259|PROSITE:PS50030"
FT DOMAIN 640..700
FT /note="Tudor"
FT /evidence="ECO:0000259|PROSITE:PS50304"
FT REGION 319..359
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 393..478
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 579..598
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 337..351
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 401..424
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 451..471
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 743 AA; 83872 MW; E81213BDBB4AB12A CRC64;
MEQVFSIRYL SDEGIEACRN SSDKVNISDI ILVALNTDLR TIGKKFLPSD INGGKVEKLE
GPCVLQIQKI RNVAAPKDNE ESQAAPRMLR LQMTDGHTSC TAIEYNYMSK ISLNTPPGTK
IKLSGIVDVK NGFLLLDDSN IVVLGGEVEH LIEKWELQRS LAKHNRSNIG TEGGPPPFVP
FGQKCVSHVQ VDSRELDRRK TLQVTSATKT VGENDEFEKQ RTAAIAEVAK SKETKTFGGG
GGNTRSNLSV SAGGNRNREV FQKEKITKPE GKNEGVYREL VDEKALKHIT EMGFSKEAAR
QALMDNSNSL EAALNFLLNS SKQKPVQGPP PRGKGKGRGR VRPDDEEELG NARPSAPSTL
FDFLESKMGT LTVEEPKSQF QPQHQVQHKV FSTEQNGIKE NNPRHLSRSD SRQPRNEKPP
RFQRDIQNSR QALEGSGPPR NRGPERHNSL GSEQWTEEKN KCDRPNPRND RPKDLAYPTV
TYQSDFSFKR RDNNMQNRLG KGALFTELKE NSGIQDTISN NNLKRGKREN QIHNPDNFYD
RKARTISNET FSLKSEQHFG MNSEYQNPIR TDSFNAIPNG DTEHPQKGRR VGPIKSPGSN
VTSTFDDKIL YYNTGPKRRS GPIKPEKILE PSIPVEYGKS WRPGDECFAL YWEDNKFYRA
EIEALHSSGT TAVVKFCDYG NYEEVLLSNI RPIHADAWEE EETYEQTLEF RRGGNIKQFS
QKKSHFLTDS PMLLKTSRRT DFS
//
