ID A0A151MJB6_ALLMI Unreviewed; 1564 AA.
AC A0A151MJB6;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Eukaryotic translation initiation factor 4 gamma 3 {ECO:0008006|Google:ProtNLM};
GN ORFNames=Y1Q_0023290 {ECO:0000313|EMBL:KYO24625.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO24625.1};
RN [1] {ECO:0000313|EMBL:KYO24625.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO24625.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- SIMILARITY: Belongs to the eukaryotic initiation factor 4G family.
CC {ECO:0000256|ARBA:ARBA00005775}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO24625.1}.
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DR EMBL; AKHW03006061; KYO24625.1; -; Genomic_DNA.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR CDD; cd11559; W2_eIF4G1_like; 1.
DR Gene3D; 1.25.40.180; -; 3.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR045208; IF4G.
DR InterPro; IPR003891; Initiation_fac_eIF4g_MI.
DR InterPro; IPR003890; MIF4G-like_typ-3.
DR InterPro; IPR003307; W2_domain.
DR PANTHER; PTHR23253; EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA; 1.
DR PANTHER; PTHR23253:SF23; EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA 3; 1.
DR Pfam; PF02847; MA3; 1.
DR Pfam; PF02854; MIF4G; 1.
DR SMART; SM00544; MA3; 1.
DR SMART; SM00543; MIF4G; 1.
DR SUPFAM; SSF48371; ARM repeat; 3.
DR PROSITE; PS51366; MI; 1.
DR PROSITE; PS51363; W2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000050525}.
FT DOMAIN 1210..1332
FT /note="MI"
FT /evidence="ECO:0000259|PROSITE:PS51366"
FT DOMAIN 1405..1564
FT /note="W2"
FT /evidence="ECO:0000259|PROSITE:PS51363"
FT REGION 63..169
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 262..324
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 340..559
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1092..1209
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1531..1564
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 845..876
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 94..133
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 150..169
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 271..287
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 397..418
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 425..442
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 448..516
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1092..1115
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1125..1151
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1177..1191
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1547..1564
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1564 AA; 173739 MW; 4FA78B6CC8F140ED CRC64;
MNLFSVRDLI TGQLALAVNV TKGAEWIFKQ AARIPRGPVQ QPLEDRIFTP TVSAVYSTVT
QVARQPGPPA PSPYSAHEIN KGHPNLAATP PGHASSPGLS QAPYPSGQNA APTTLVYPQA
PQTMNTQPQT RSPFAAGPRP AHHQFFQRPQ IQPPRATIQN SSPSIRPGAQ TPTAVYQTNQ
HIMMVNHLPM PYPMPQGPQY CIPQYRHSGP PYVGPPQQYP VQPPGPGPFY PGPGPGEFPN
AYGTPFYPSQ PVYQSAPIIV PTQQQQPPPA KREKKTIRIR DPNQGGKDIT EEIMSGGGSR
NPTPPIVRPT STPTPPQLSS QVPEHSPVVY ATVESTPLAA TTTVTATSDP KQEEKPKPDP
VLKSPSPALR PEPSGEKKDQ AGQTSEAAVG DLEGEESTRT TISEEVKDTQ KKEDTEADGQ
PEEIAESPSL NSRKSPVPAQ TAVTAPKTWK KPKDRTQATE EVLEAETEPK VEEELSGDKV
LESEQDKMSH GFQLERDPSE LKKTKAVEEN GEQEAEPVRN GAESVSEGEG PDANSGVTEG
STEGPVYQYK PEQWKPVDPE GKKQYDREFL LDFQFMPACI QKPEGLPPIS DVVLDKVRGD
PIKQINQPKL PVRTLDPRIL PRGPDFTPAF ADFGRQASGG RGVSGSACKM QSNPGLPSLA
RCGTPACPLL VSSHPPLRNL PMGLLNVGPR RSQPGQRREP RKIITVCVKE DVHLKKAENA
WKPSLKRDSQ AEDPENIKTQ ELFRKVRSIL NKLTPQMFNQ LMKQVTDLTV DTEERLKGVI
DLVFEKAIDE PSFSVAYANM CRCLVTLKVP MADKPGSTVN FRKLLLNRCQ KEFEKDKADD
DVFEKKQKEL EAASASEEKT RLRDELEEAR DKARRRSIGN IKFIGELFKL KMLTEAIMHD
CVVKLLKNHD EESLECLCRL LTTIGKDLDF EKAKPRMDQY FNQMEKIVKE RKTSSRIRFM
LQDVIDLRLC NWVSRRADQG PKTIEQIHKE AKIEEQEEQR KVQQLMTKEK RRPGVQRVDE
GGWNTVQGAK SSRVLDPTKF LKITKPTIDD KIQLVPKAQL GSWGKGSSGG AKASEIDSLR
PSATSLNRFS ALQPPVSSVS ASSASSELDS RRALTSRGST GREKNDKPLP SSVTRPSTFL
RGSSSKELLL DNQAQEEQRR EMLETVKQLT GGMEIDRNSA EADRNKAKET AKPETATAPV
QDKPSLSEEE MERKCKSIID EFLHINDYKE AMQCVEELNA QNLLPVFVRV GVESTLERSQ
ITRDHMGQLL HQLVQSGKLS KQDFFKGFSD TLEMADDMAI DIPHIWLYLA ELVTPMLKEG
GISMRELITE FSKPLLPVGR AGVLLSEILH LLCKQMSHKK VGALWREAGL SWKDYLPEGE
DVHTFLMEQK LDFTESDCSS SSEALSEKDL SAEELNKQLE KLIIEDKTND EQIFDWVEAN
LDESQMSSPT FLRALMTAVC KAAIIADSSS FRVDTAVIKQ RVPILLKYLD SDTEKELQAL
YALQASIVKL DQPPNLLRMF FDCLYDEECS KANSRAEPPP SPTHARVGEE TIDKHKGDHG
GNKL
//
