ID A0A151MJC0_ALLMI Unreviewed; 1565 AA.
AC A0A151MJC0;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Eukaryotic translation initiation factor 4 gamma 3 {ECO:0008006|Google:ProtNLM};
GN ORFNames=Y1Q_0023290 {ECO:0000313|EMBL:KYO24624.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO24624.1};
RN [1] {ECO:0000313|EMBL:KYO24624.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO24624.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- SIMILARITY: Belongs to the eukaryotic initiation factor 4G family.
CC {ECO:0000256|ARBA:ARBA00005775}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO24624.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AKHW03006061; KYO24624.1; -; Genomic_DNA.
DR STRING; 8496.A0A151MJC0; -.
DR eggNOG; KOG0401; Eukaryota.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR CDD; cd11559; W2_eIF4G1_like; 1.
DR Gene3D; 1.25.40.180; -; 3.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR045208; IF4G.
DR InterPro; IPR003891; Initiation_fac_eIF4g_MI.
DR InterPro; IPR003890; MIF4G-like_typ-3.
DR InterPro; IPR003307; W2_domain.
DR PANTHER; PTHR23253; EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA; 1.
DR PANTHER; PTHR23253:SF23; EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA 3; 1.
DR Pfam; PF02847; MA3; 1.
DR Pfam; PF02854; MIF4G; 1.
DR SMART; SM00544; MA3; 1.
DR SMART; SM00543; MIF4G; 1.
DR SUPFAM; SSF48371; ARM repeat; 3.
DR PROSITE; PS51366; MI; 1.
DR PROSITE; PS51363; W2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000050525}.
FT DOMAIN 1211..1333
FT /note="MI"
FT /evidence="ECO:0000259|PROSITE:PS51366"
FT DOMAIN 1406..1565
FT /note="W2"
FT /evidence="ECO:0000259|PROSITE:PS51363"
FT REGION 63..169
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 262..325
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 341..560
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1093..1210
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1532..1565
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 846..877
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 94..133
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 150..169
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 271..287
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 398..419
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 426..443
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 449..517
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1093..1116
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1126..1152
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1178..1192
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1548..1565
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1565 AA; 173867 MW; 433689A3A7C245C0 CRC64;
MNLFSVRDLI TGQLALAVNV TKGAEWIFKQ AARIPRGPVQ QPLEDRIFTP TVSAVYSTVT
QVARQPGPPA PSPYSAHEIN KGHPNLAATP PGHASSPGLS QAPYPSGQNA APTTLVYPQA
PQTMNTQPQT RSPFAAGPRP AHHQFFQRPQ IQPPRATIQN SSPSIRPGAQ TPTAVYQTNQ
HIMMVNHLPM PYPMPQGPQY CIPQYRHSGP PYVGPPQQYP VQPPGPGPFY PGPGPGEFPN
AYGTPFYPSQ PVYQSAPIIV PTQQQQPPPA KREKKTIRIR DPNQGGKDIT EEIMSGGGSR
NPTPPIVRPT STPTPPQQLS SQVPEHSPVV YATVESTPLA ATTTVTATSD PKQEEKPKPD
PVLKSPSPAL RPEPSGEKKD QAGQTSEAAV GDLEGEESTR TTISEEVKDT QKKEDTEADG
QPEEIAESPS LNSRKSPVPA QTAVTAPKTW KKPKDRTQAT EEVLEAETEP KVEEELSGDK
VLESEQDKMS HGFQLERDPS ELKKTKAVEE NGEQEAEPVR NGAESVSEGE GPDANSGVTE
GSTEGPVYQY KPEQWKPVDP EGKKQYDREF LLDFQFMPAC IQKPEGLPPI SDVVLDKVRG
DPIKQINQPK LPVRTLDPRI LPRGPDFTPA FADFGRQASG GRGVSGSACK MQSNPGLPSL
ARCGTPACPL LVSSHPPLRN LPMGLLNVGP RRSQPGQRRE PRKIITVCVK EDVHLKKAEN
AWKPSLKRDS QAEDPENIKT QELFRKVRSI LNKLTPQMFN QLMKQVTDLT VDTEERLKGV
IDLVFEKAID EPSFSVAYAN MCRCLVTLKV PMADKPGSTV NFRKLLLNRC QKEFEKDKAD
DDVFEKKQKE LEAASASEEK TRLRDELEEA RDKARRRSIG NIKFIGELFK LKMLTEAIMH
DCVVKLLKNH DEESLECLCR LLTTIGKDLD FEKAKPRMDQ YFNQMEKIVK ERKTSSRIRF
MLQDVIDLRL CNWVSRRADQ GPKTIEQIHK EAKIEEQEEQ RKVQQLMTKE KRRPGVQRVD
EGGWNTVQGA KSSRVLDPTK FLKITKPTID DKIQLVPKAQ LGSWGKGSSG GAKASEIDSL
RPSATSLNRF SALQPPVSSV SASSASSELD SRRALTSRGS TGREKNDKPL PSSVTRPSTF
LRGSSSKELL LDNQAQEEQR REMLETVKQL TGGMEIDRNS AEADRNKAKE TAKPETATAP
VQDKPSLSEE EMERKCKSII DEFLHINDYK EAMQCVEELN AQNLLPVFVR VGVESTLERS
QITRDHMGQL LHQLVQSGKL SKQDFFKGFS DTLEMADDMA IDIPHIWLYL AELVTPMLKE
GGISMRELIT EFSKPLLPVG RAGVLLSEIL HLLCKQMSHK KVGALWREAG LSWKDYLPEG
EDVHTFLMEQ KLDFTESDCS SSSEALSEKD LSAEELNKQL EKLIIEDKTN DEQIFDWVEA
NLDESQMSSP TFLRALMTAV CKAAIIADSS SFRVDTAVIK QRVPILLKYL DSDTEKELQA
LYALQASIVK LDQPPNLLRM FFDCLYDEEC SKANSRAEPP PSPTHARVGE ETIDKHKGDH
GGNKL
//
