ID A0A151ML54_ALLMI Unreviewed; 329 AA.
AC A0A151ML54;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=GRAM domain-containing protein 2 isoform A {ECO:0000313|EMBL:KYO25291.1};
GN Name=GRAMD2 {ECO:0000313|EMBL:KYO25291.1};
GN ORFNames=Y1Q_0010006 {ECO:0000313|EMBL:KYO25291.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO25291.1};
RN [1] {ECO:0000313|EMBL:KYO25291.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO25291.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO25291.1}.
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DR EMBL; AKHW03005879; KYO25291.1; -; Genomic_DNA.
DR RefSeq; XP_019354912.1; XM_019499367.1.
DR AlphaFoldDB; A0A151ML54; -.
DR STRING; 8496.A0A151ML54; -.
DR CTD; 196996; -.
DR eggNOG; KOG1032; Eukaryota.
DR OrthoDB; 45896at2759; -.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd13220; PH-GRAM_GRAMDC; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR004182; GRAM.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR042624; RAMD2A.
DR PANTHER; PTHR46973; GRAM DOMAIN-CONTAINING PROTEIN 2A; 1.
DR PANTHER; PTHR46973:SF1; GRAM DOMAIN-CONTAINING PROTEIN 2A; 1.
DR Pfam; PF02893; GRAM; 1.
DR SMART; SM00568; GRAM; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000050525};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 286..306
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 77..144
FT /note="GRAM"
FT /evidence="ECO:0000259|SMART:SM00568"
FT REGION 1..44
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 30..44
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 329 AA; 37403 MW; 7D5FAF690F4DF6D6 CRC64;
MRSVQKTLLP HSSTKPMHEK AASLKSSQPM HNREKLEASH KEKSLDSLDG SLHLNEGLKD
EEVKKCHREV TSSKYNLQYH KLFKDIPTEE SVLKVCSCAL QRDILIQGRL YISPNWLCFY
ANLFGKDIKV VIPVVSVQLI KKHKTARLLP NGLAITTNAS RKYIFVSLIS RDSVYDVLKR
VCTHLQVSSK KSLSLKEFTE EPDSVSLEVI VPEVKWRKVS PASLSLSLPN ADYQCIHRTS
ISSVSTKESS FNSEEPLVSE SAINTEEELE AEPNCVAELR PSDYQLLKIF IVLICLLVVS
SSYLAFRIFR LEQQLCSLNR DYLSRGHRR
//
