ID A0A151MRJ9_ALLMI Unreviewed; 1877 AA.
AC A0A151MRJ9;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Protein NLRC5 isoform A {ECO:0000313|EMBL:KYO27030.1};
GN Name=NLRC5 {ECO:0000313|EMBL:KYO27030.1};
GN ORFNames=Y1Q_0018195 {ECO:0000313|EMBL:KYO27030.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO27030.1};
RN [1] {ECO:0000313|EMBL:KYO27030.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO27030.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO27030.1}.
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DR EMBL; AKHW03005442; KYO27030.1; -; Genomic_DNA.
DR eggNOG; KOG4308; Eukaryota.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR Gene3D; 1.10.533.20; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 5.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR006553; Leu-rich_rpt_Cys-con_subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR007111; NACHT_NTPase.
DR InterPro; IPR041210; NLRC5_atypical_Card.
DR InterPro; IPR041267; NLRP_HD2.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR24106; NACHT, LRR AND CARD DOMAINS-CONTAINING; 1.
DR PANTHER; PTHR24106:SF281; PROTEIN NLRC5; 1.
DR Pfam; PF18461; Atypical_Card; 1.
DR Pfam; PF13516; LRR_6; 10.
DR Pfam; PF05729; NACHT; 1.
DR Pfam; PF17776; NLRC4_HD2; 1.
DR SMART; SM00367; LRR_CC; 12.
DR SMART; SM00368; LRR_RI; 17.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52047; RNI-like; 3.
DR PROSITE; PS50837; NACHT; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000050525}.
FT DOMAIN 257..393
FT /note="NACHT"
FT /evidence="ECO:0000259|PROSITE:PS50837"
FT REGION 125..163
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1007..1026
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 125..140
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1877 AA; 211226 MW; 573BF4F9116C95DB CRC64;
MCGQTMLRCS TTCFPGTALE PNRVPLQMDD LDLQHVIAKV RPQLVEFLSH NSEWLIMKAK
HFLPLVDLKY VDDITDCKQK VSELLDRLEN VELTIQKQFV QCICMECNLP MDLEIQLMSS
AGEGNLNQQQ ETQSPSSQFA GPGRRRPGGN SAAIDKESKQ QRLDSAERYR HLLISSMNQR
YRSQRAPEAT VLGQVQPPAC HQLFVNLVIR QSKASRLKER LDKPKEDLAG SPEAEEVADT
AVKVSDLFDT ISSGTTRVIL LFGKPGTGKT MLMHRICQKW AEGSLHQFLL TFLFEFRQLN
LISQKLTLKE LLFDFSLQPE DCPDAVFQHL LENAKQVLII FDGLDEFVGN TGVSSSPEMH
PAFPRPMSIS ELFTDLCDGK LLPGCTVLIT SRPKKCPDFL LNTVDLLAEI WGFDHEKVEE
YVNHYFHEHA FKEQAIAQLK NNSKLLSMCF IPALCYIVCI CLEYLLIKQL LSVELPQTMT
QFYIQMLLIF ISKQQKERSQ RDEVQLNHYR VAILGLCELA LKGLEEKKLV FYVDDIPEHV
KEFASLHGLL TVFEVKRSDH RPEAGYAFVH LSLQEFFAAL CVMLSKTADR NYLRKKFSLK
SKWTLKNEAR TEFMESFHIF LSGLSSKDCR KFLAQLSEQN EAWVQAKQAV ILQSLKKLAA
TNLTGPKIIE LCHCTYETQD LEVAQHVGSQ LNFKYEFKNF RLTPLDISAL VFVINCGQEL
THLDFAGCPM ELDCLEVLAS CTNIECLSFR SRKCGDEFAA VLSRTLPKIR SLKKLELTGG
NITALGLANL GQAFPHCTQL EEINLQGNRM RDQDMTKVLE VFSRMEKLKK IDLSHNDIST
KAVLVLAKRA IMCPNVTELH IRGDTIIILF SGHPETVSRS ASLRRKTRKE NAAQMRHVML
RLQDCSLDSH HTEEITAVLR GCSQLSEVDL SGNHLGDEGC RQLVESLPEV QISKCLDLSN
NHISVDGICC VLNSMNTCLN LVEIEASLHH QTAILKFEGA EAFASTQSRD TSSYGDQLGG
NESQKPMVPR RIRVTDSHFP RNDLEKLCTV LKHCSRVTAL DLANNSLGDQ GVEKLVQFLP
QLKTLSSLGL SGNQISLSTV FCLAQALSLL EHIKTVDISL GKAQLILLTF QEGVRVRNTR
RSAGRSLALP QPSGSARCFR LRECMVGPED MDKLCQILAG GTELSEIDLS KNALNDQSIQ
RLLTFLPRLH SLNLLSIRNN KLSPRCTLLL ANSINLCERI REVEVRCSEN AFLCLAKNMK
IQEISCRLTS CSIGPNEIQD LCKILEQCDH LAELDLSGNQ LGNEGLRCLL AHLPRLHVSH
LMNLSHNNIS QHGVMHLINA LTTSRNVSEV QVSLCTEETS LIKFTREDEP KKILRLTKCN
FQQEHSLQLC SLLEKCNYLT EYISAKNSMT MRAVENLLRA LRKSLGMLRI SIDEPWVCDK
DLLTLLELAV QVQGNIIEIT ILKDKGLFKV GEEFPYRMEK MEDVVSRLNQ CELEAKHLHF
LQRVIEKCTQ LQELRWSHID LNNTEAATLA RALLSLPELK KFELTSSTIV PIGIRQLVAG
LQQCHGLEEL NLGFLKLDDI AIQMLVPSIC KMPSLKRLIL NNNSIGNEGC IHLAEALKDT
HRLEEINLSL NKFEDVGLVK IATTLLEMQN LKKINFSGNS IGPVGGEKLI EALSHCKQVE
ELLLARIVVG DKAAAQLSLC LPGMCHLKIL HLQSNGISSL GGTQMARALV KCQQLEEISL
SENNIGEEGI HALSEGLLHF PQLRRIELKL CEIGDGVSKP LVFGFSQCPF IEEIILPWNH
LGDDSAFELA EILPGMTKLR ILDLDKNRIS ARGASRLAEE LTKCYGIQVI RLWNNAIAKD
VEENLMRQDS RLHFSFF
//
