ID A0A151MUS2_ALLMI Unreviewed; 485 AA.
AC A0A151MUS2;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Erythroid transcription factor {ECO:0000313|EMBL:KYO28252.1};
GN Name=GATA1 {ECO:0000313|EMBL:KYO28252.1};
GN ORFNames=Y1Q_0020309 {ECO:0000313|EMBL:KYO28252.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO28252.1};
RN [1] {ECO:0000313|EMBL:KYO28252.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO28252.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO28252.1}.
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DR EMBL; AKHW03004950; KYO28252.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A151MUS2; -.
DR SMR; A0A151MUS2; -.
DR STRING; 8496.A0A151MUS2; -.
DR eggNOG; KOG1601; Eukaryota.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd00202; ZnF_GATA; 2.
DR Gene3D; 3.30.50.10; Erythroid Transcription Factor GATA-1, subunit A; 2.
DR Gene3D; 3.40.800.20; Histone deacetylase domain; 1.
DR InterPro; IPR037138; His_deacetylse_dom_sf.
DR InterPro; IPR039355; Transcription_factor_GATA.
DR InterPro; IPR023696; Ureohydrolase_dom_sf.
DR InterPro; IPR000679; Znf_GATA.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR PANTHER; PTHR10071:SF190; ERYTHROID TRANSCRIPTION FACTOR; 1.
DR PANTHER; PTHR10071; TRANSCRIPTION FACTOR GATA FAMILY MEMBER; 1.
DR Pfam; PF00320; GATA; 2.
DR PRINTS; PR00619; GATAZNFINGER.
DR SMART; SM00401; ZnF_GATA; 2.
DR SUPFAM; SSF52768; Arginase/deacetylase; 1.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 2.
DR PROSITE; PS00344; GATA_ZN_FINGER_1; 2.
DR PROSITE; PS50114; GATA_ZN_FINGER_2; 2.
PE 4: Predicted;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000050525};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00094}.
FT DOMAIN 220..275
FT /note="GATA-type"
FT /evidence="ECO:0000259|PROSITE:PS50114"
FT DOMAIN 274..327
FT /note="GATA-type"
FT /evidence="ECO:0000259|PROSITE:PS50114"
FT REGION 325..354
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 337..354
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 485 AA; 51969 MW; 08CE21BF32A2FC86 CRC64;
MDPGIWAPEA PSMPRPYPAL LCHLRLSVGP SASAGAGNKG ALKGWRRGSP MEFATLEAPE
GSPSFLEAPA LPPTEEAAPF LSTPEAPDPG ALASLFSRTP ESFRHSPGCQ LYPVLGALPW
GEGSAFTAGG WAPGGYSKAL PGPPSPPPPP EARDSPTFLE MLKTERPSPG VGGGTEGLGL
GLGLSLGLGG GYGSPPDLAY LAPPGPAYPP AFRGSLPLAS CEARECVNCG ATATPLWRRD
GTGHYLCNAC GLYHRVNGAN RPLIRPKKRL VVSKRAGTQC SNCQTTTTTL WRRDPRGQPV
CNACGLYYKL HNVNRPLTMR KDGIQTRNRK VSAKGKKRRS GEPGLPEAKR RGRARRLHQE
VAELQDGLQH LDLAAEKPVP SGTGLAYDKE LTSFHCLWDK SFPECPARLT SIWTKLVEDG
LVERCVPVQA RLATEEEILL VHSPQFLALM ASTADMEEGK LRALSDTYDS VYLHPVSPRF
WGRGA
//
