ID A0A151MYK6_ALLMI Unreviewed; 872 AA.
AC A0A151MYK6;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Sodium bicarbonate transporter-like protein 11 isoform B {ECO:0000313|EMBL:KYO29538.1};
GN Name=SLC4A11 {ECO:0000313|EMBL:KYO29538.1};
GN ORFNames=Y1Q_0004939 {ECO:0000313|EMBL:KYO29538.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO29538.1};
RN [1] {ECO:0000313|EMBL:KYO29538.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO29538.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the anion exchanger (TC 2.A.31) family.
CC {ECO:0000256|ARBA:ARBA00010993}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO29538.1}.
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DR EMBL; AKHW03004653; KYO29538.1; -; Genomic_DNA.
DR RefSeq; XP_006276137.2; XM_006276075.3.
DR AlphaFoldDB; A0A151MYK6; -.
DR GeneID; 102562043; -.
DR KEGG; amj:102562043; -.
DR CTD; 83959; -.
DR eggNOG; KOG1172; Eukaryota.
DR OrthoDB; 1013180at2759; -.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005452; F:solute:inorganic anion antiporter activity; IEA:InterPro.
DR GO; GO:0006820; P:monoatomic anion transport; IEA:InterPro.
DR Gene3D; 1.10.287.570; Helical hairpin bin; 1.
DR InterPro; IPR011531; HCO3_transpt-like_TM_dom.
DR InterPro; IPR003020; HCO3_transpt_euk.
DR InterPro; IPR016152; PTrfase/Anion_transptr.
DR PANTHER; PTHR11453; ANION EXCHANGE PROTEIN; 1.
DR PANTHER; PTHR11453:SF82; SOLUTE CARRIER FAMILY 4 MEMBER 11; 1.
DR Pfam; PF00955; HCO3_cotransp; 1.
DR PRINTS; PR01231; HCO3TRNSPORT.
DR SUPFAM; SSF55804; Phoshotransferase/anion transport protein; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000050525};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 358..380
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 401..422
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 442..464
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 557..578
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 590..611
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 631..657
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 678..701
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 742..762
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 812..831
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 837..855
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 327..817
FT /note="Bicarbonate transporter-like transmembrane"
FT /evidence="ECO:0000259|Pfam:PF00955"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 872 AA; 98070 MW; 2B3E1489C254F6ED CRC64;
MKAEPNATED KGNVPSAGKE SPPAAMSRNG YFFEETGYLK CDTDDGCENK EEAGGEELFD
TVNSSIVSGD SIRFFVNVNL DVQQNVAAEN ENAGCVLLHT SRKYLKLKNF EEEVRAHRDL
DGFLARASII LDETATSLDD VLREMLKHFA EDPDNMEPSC NFEKIMSTLF TDSGTPREGN
VHLLSDTIQG VTATVTGVQY QQSWLCIICT IKSLQRRHVC ISRLERPQNW GENSCEVRFV
ILVLAPPKMK STKTATEVGR TFATMFSDIT FRQKLLETKT EEEFKEALVH QRHLLTVVNQ
RPSAVNDGHK THSHKPLKLH DFFNVGKGIF DDIARRFPVY ALDFTDGIIG NNKAIGKYIT
TMIFLYFACL LPSIAFGSLN DENTGGAIDV QKTIVGQCIG GLLYALFSGQ PLVVLLTTAP
LALYINVIRG ICDDYNLDFS AFYAWIGLWN SFFLVLYSLF NFSLVMKLFK RSTEEIIALF
ISITFVFDAI KGIIKVFKKY YYQEPGGESY LKSTRMEALP SLDVNTTFLM NSSASRSMSL
GNQTGVNDVV HYGRETAVLS LMLMLGTLWL GHTLYQFKKS PYLHARVREI LSDCALPISV
LTFSIVGSYI FKEIEMSKFN YNPSESLFVL APVRSLSIGS VMSAMGLGFL LSMLFFIEQN
IVASLTNAPE NRLVKGTAYH WDLLLVALIN TGLSVFGLPW IHAAFPHSPM HVRALAYVEE
RVENGHIYET IVSVKETRLT SLVANFLVGL SLLLLPFPLQ WIPKPVLYGL FLYIALTSID
GNQLFERVAL LLKEQTAYPP THYIRRVPQR KIHYFTGLQV LQLFILCGFG MSPLPYMKMI
FPLIMIGMIP IRYNLLPRII EAKYLDAMDA EH
//
