ID A0A151N2Y1_ALLMI Unreviewed; 978 AA.
AC A0A151N2Y1;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 22-FEB-2023, entry version 19.
DE SubName: Full=Monocarboxylate transporter 6-like {ECO:0000313|EMBL:KYO31132.1};
GN Name=SLC16A5 {ECO:0000313|EMBL:KYO31132.1};
GN ORFNames=Y1Q_0016481 {ECO:0000313|EMBL:KYO31132.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO31132.1};
RN [1] {ECO:0000313|EMBL:KYO31132.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO31132.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO31132.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AKHW03004113; KYO31132.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A151N2Y1; -.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd17425; MFS_MCT6; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 4.10.830.40; -; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR003877; SPRY_dom.
DR PANTHER; PTHR11360; MONOCARBOXYLATE TRANSPORTER; 1.
DR PANTHER; PTHR11360:SF21; MONOCARBOXYLATE TRANSPORTER 6; 1.
DR Pfam; PF07690; MFS_1; 1.
DR Pfam; PF00622; SPRY; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000050525};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 513..539
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 555..575
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 582..601
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 607..633
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 640..659
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 671..690
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 754..775
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 787..807
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 819..839
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 845..867
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 879..898
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 910..933
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 279..476
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT DOMAIN 514..939
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
FT REGION 460..481
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 694..724
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 943..969
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 700..714
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 978 AA; 108585 MW; B7223DD669148BC3 CRC64;
MTKLPPAGPN NIPCDFCSSG KLKPIKTCLQ HTPSLCETHT QLHYKDKVYR SHQLLEPISD
LKARLCLKHH KLQKQNCRAE GSFLGHTRLQ EGRRNHEAVP LQGERATKAV ENEQVQVNME
NQIIMMASDG HRHKERVIYL MRVVKNARDE VNQTFAEIIK ELKIMQVKVL EFLDKEEKAA
LVQMGNSIQQ NQVKLADLWK QSLWMTGLLE NTSDQQFVQE FPKLKQLGAC PERVVSLKCE
ESSSFIGVKQ MLSDLKAQLA VVALHFVNKI LKTGITMQPY EVIPPNMDRK TLLKYYCNLN
FDPNTTSEEL LLFKETHSVL NIGIMLESSS MPCQGFNHWP QVLCTQSLCG GCHYWEVEVS
DSWLCLGATY SYAHRTGKNY IYLIGRNSTS WCLEWDSLKF SVWHNNIQTV VKGSYYQTVG
IFLDYAAGSL TFYGVTNTMN LIYHFLTTFT EPLYPAAMAA PQEEQRGGRR RGGSGVAPHG
GARVNRSAWQ KVKADMSGGG AVHGTSKAQD RGWAWMVLLA TVLVQGLTLG FPSCVGVFFT
DLQHEFQATN SETSWFPSIM TALLHAGGPL CSVLVERFGC RLTVMLGGLL SGVGMVTSSF
SKSISQLYIT AGFITGLGSC FSFQAGVTVL GYYFVRRRAL ANAVASTGVS IGLTLWPLIS
QYLLDEMGWR NTFLIFGGVQ LNCCVCGAIM RPVQHKSPSP RQVPEETTEG AQLSNGAGPH
PAEPPQQGRF ATCCRILQKY LAFDVFYKNK GYQIYTIGVT WMVMGFVLPL IYLVPYATQN
GVEERKAALL ISIIGFINIF MRPMAGLLSG LNIFAGRRIY LFSLAVLLNG LSNLICVISA
DFTVLVLYCL IYSVSMSGIG ALVFQVLMDV VEMDRFSSAL GLFTILESIT ILIGPPLIGL
LVDLTGQFSY VFYASSFFMV SAALFMGLSF CALEKKNKLK EAPKVTGDSP SKYQYTEVPS
KPEAEGQAPP AVMYITSI
//
