ID A0A151N5A4_ALLMI Unreviewed; 863 AA.
AC A0A151N5A4;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Complement component 1 Q subcomponent-binding protein, mitochondrial {ECO:0000256|ARBA:ARBA00021918};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN ORFNames=Y1Q_0007049 {ECO:0000313|EMBL:KYO32023.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO32023.1};
RN [1] {ECO:0000313|EMBL:KYO32023.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO32023.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001556};
CC -!- SIMILARITY: Belongs to the MAM33 family.
CC {ECO:0000256|ARBA:ARBA00005457}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO32023.1}.
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DR EMBL; AKHW03004004; KYO32023.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A151N5A4; -.
DR STRING; 8496.A0A151N5A4; -.
DR eggNOG; KOG0922; Eukaryota.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR GO; GO:0005759; C:mitochondrial matrix; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW.
DR CDD; cd17978; DEXHc_DHX33; 1.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.10.280.10; Mitochondrial glycoprotein; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR003428; MAM33.
DR InterPro; IPR036561; MAM33_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF118; ATP-DEPENDENT RNA HELICASE DHX33; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF02330; MAM33; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF54529; Mitochondrial glycoprotein MAM33-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW Adaptive immunity {ECO:0000256|ARBA:ARBA00023130};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Immunity {ECO:0000256|ARBA:ARBA00023130};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000050525}.
FT DOMAIN 35..203
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 228..401
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 724..746
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 863 AA; 96385 MW; 4F6809F06349DC05 CRC64;
MLLASPGAKR PPAPSTAGEA QRRSLPIFQA RGPLLARLRA LDTAVLIGET GSGKTTQIPQ
YLYEAGIGHQ GIVAVTQPRR VAAISLATRV SDEKKTKLGK LVGYTVRFED LTSEGTRIKF
LTDGMLLREA IGDPLLRKYS VVILDEAHER TIHTDVLFGV VKAAQKKRKE LGKLPLKVVV
MSATMDVDQF SQYFNGAPVL YLEGRQHPIQ IFYTKQPQSD YLQAALVSVF QIHQEAPSSQ
DILVFLTGQE EIEAMTKTSR DIAKHLPDGC PQMVVLPLYA SLPYSQQLRV FQSAPKGYRK
VILSTNIAET SITITGIKYV LDTGMVKAKK YNPESGLEVL AVQRVSKAQA WQRTGRAGRE
DSGICYRLYT EDEFEKFDKM TIPEIQRCNL ANVMLQLLAL RIPNVLTFDF MSKPSPDAIQ
AAIEQLDLLG AVERKEDQLV LTPLGRKMAA FPLEPKFSKT ILVSPKYHCT EEILTIISLL
SVDSVLYNPP SRRDEVQAVR KKFISSEGDH LTLLSVYRAF KSVSGNKEWC KENFVNGRNM
LLVSDVRAQL RDICVKLSMP IESSRSDTGN IRRCLAHSLF MNAAELQPDG TYVTADTHQL
VAIHPSSVLF HCKPACVLYN ELLHTNKCYM RDLCVAGGPR PSALLRPPPG LSFGCGGLHT
EGDKVFSEFL MDEIKQEKKI QKHKSLPEMS GGWELEVQGT EAKLLRNVSG EKISVTFNIN
NSIPPVIDEE PQEGQKADEQ ESDLTSTPNF VVEVTKDDSK NTLVFDCHFP ENESGNEGEE
ESDIFAIQEV SFQPSEKSDW KETNFTLNTD SLDWALYDHL MDFLADRGVD NTFADELVEL
STALEHQEYI KFLEDLKGFV KCQ
//
