ID A0A151N7Z0_ALLMI Unreviewed; 612 AA.
AC A0A151N7Z0;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Leucine-rich repeat and calponin-like proteiny domain-containing protein 2 {ECO:0000313|EMBL:KYO32709.1};
GN Name=LRCH2 {ECO:0000313|EMBL:KYO32709.1};
GN ORFNames=Y1Q_0009320 {ECO:0000313|EMBL:KYO32709.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO32709.1};
RN [1] {ECO:0000313|EMBL:KYO32709.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO32709.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO32709.1}.
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DR EMBL; AKHW03003879; KYO32709.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A151N7Z0; -.
DR STRING; 8496.A0A151N7Z0; -.
DR eggNOG; KOG0532; Eukaryota.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR CDD; cd21271; CH_LRCH2; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR48051; -; 1.
DR PANTHER; PTHR48051:SF14; LEUCINE-RICH REPEAT AND CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN 2 ISOFORM X1; 1.
DR Pfam; PF00307; CH; 1.
DR Pfam; PF13855; LRR_8; 1.
DR SMART; SM00033; CH; 1.
DR SMART; SM00364; LRR_BAC; 4.
DR SMART; SM00369; LRR_TYP; 4.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS50021; CH; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Reference proteome {ECO:0000313|Proteomes:UP000050525};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 489..602
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT REGION 160..244
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 333..400
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 412..478
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 298..325
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 482..509
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 207..224
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 225..244
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 333..376
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 426..446
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 612 AA; 69760 MW; B1D3E1BD8EAD77C6 CRC64;
MLTYLNISRN LLSTLPKYLF DLPLKVLVVS NNKLVSIPEE IGKLRDLMEL DVSCNEIQVL
PQQIGKLQSL RELNIRRNNL HMLPDELGDL PLVKLDFSCN KVTEIPVCYR KLRHLQVIIL
DNNPMQIPPA QICLKGKVHI FKFLSIQACL RIDKKPDSLD LPSLGKRIPS QPLTDSMEDF
YPNKNHGPDS GIGSDNGDKR LSTTEPSDDD TISLHSQVSE STREQTLRND NHLIGNKHDS
QKDQEVDDYI DPNAEDAAIP EQGDVQIGPF ISYIKEQGKH PEKSQKIERN EDWGDEKRLQ
KEQLLAEEED ELKEVTDLRK IAAQLLQQEQ KNRLLNHSTS VSTRNRPKQQ TVESEKSVSA
DEANSPLSPY SWQPLENQKD ETDEQHWPET QPVIWQNEER RKSKQLRKEY FKYKSSRKSS
SGNENDEQDS DNTNVSPQSP VSSEDYERTD SNSHGPFGLK PRSAFSRTSR QDYGAVDPGF
TMRRKMEHLR EEREQIRQLR NNLESRLKVM LPDDIGAALM DGVVLCHLAN HIRPRSVASI
HVPSPAVPKL SMAKCRRNVE NFLDACKKLG VPQERLCLPH HILEERGLVK VGLTVQALLE
LPTSKASHLS SV
//
