ID A0A151NAY5_ALLMI Unreviewed; 990 AA.
AC A0A151NAY5;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Helicase-like transcription factor {ECO:0000313|EMBL:KYO33941.1};
GN Name=HLTF {ECO:0000313|EMBL:KYO33941.1};
GN ORFNames=Y1Q_0024550 {ECO:0000313|EMBL:KYO33941.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO33941.1};
RN [1] {ECO:0000313|EMBL:KYO33941.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO33941.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO33941.1}.
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DR EMBL; AKHW03003627; KYO33941.1; -; Genomic_DNA.
DR RefSeq; XP_014458311.1; XM_014602825.2.
DR AlphaFoldDB; A0A151NAY5; -.
DR STRING; 8496.A0A151NAY5; -.
DR GeneID; 102570682; -.
DR KEGG; amj:102570682; -.
DR CTD; 6596; -.
DR eggNOG; KOG1001; Eukaryota.
DR OrthoDB; 200191at2759; -.
DR PhylomeDB; A0A151NAY5; -.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProt.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016818; F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd18071; DEXHc_HLTF1_SMARC3; 1.
DR CDD; cd16509; RING-HC_HLTF; 1.
DR CDD; cd18793; SF2_C_SNF; 1.
DR Gene3D; 3.30.70.2330; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 2.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR014905; HIRAN.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR049730; SNF2/RAD54-like_C.
DR InterPro; IPR000330; SNF2_N.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR45626:SF17; HELICASE-LIKE TRANSCRIPTION FACTOR; 1.
DR PANTHER; PTHR45626; TRANSCRIPTION TERMINATION FACTOR 2-RELATED; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF08797; HIRAN; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR Pfam; PF13923; zf-C3HC4_2; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00910; HIRAN; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000313|EMBL:KYO33941.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000050525};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 404..587
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 741..782
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 818..990
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 348..411
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 430..450
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 348..368
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 372..411
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 990 AA; 111011 MW; 74048CA7F745A96A CRC64;
MFAKNYGSST GYGGNRTYSC SSSGDVDSAL GFEDFLYTDD TSGTDEDLDL FVLFGNLRGN
VVGLRYYTGV VNNNEMVALQ REPNNPYDKN AVKVNNVNGD QVGHIKKELA APLAYIIDNK
LARVEGIVPY GAKNTFTMPV QMSFWGKEEN KQAVLDRLKM HGFKMAPPLK SSELGFGSNL
FSGRAGPSYS APGHTAVQMT TEQLKSEFDK LFEDLKEDDK TREIQGPEVI GTQLLPHQKQ
ALAWMVLREN NKELPPFWEE RNNFFYNTLT NFAEKERPEN VLGGILADDM GLGKTLTTIA
LILANFHNGK PLPVEKIKRD QLYKEFGATS VKNEGDLPFK DLNCNLESST SSGKNETVQS
QLSSSYPKRT KAKKPKYSES SDSEESEEWL PQETRINTKK DLPTTRKRSK ASCNFQEDTG
FASALAAPSP TLKKKAKKKG TSSIQLAKKD DSEEGQRTTL IICPLSVLSN WIDQLEQHIS
PDVHLNVYVY YGPDRSKDPA LLSRQDIVLT TYNILASDYG SRGDSPLHKL KWLRVVLDEG
HTIRNPNALQ TKAALNLEAQ RRWILTGTPI QNSLKDLWSL LSFLKLKPFA DREWWHRTIQ
RPVMMGDQGG LRRLQSLIKN ITLRRTKMSK IKGKPVLELP ERKVFIQHVT LTEEERQIYQ
AVKNEGKLAI SRYFSEGTVL AHYADVLGVL LRLRQLCCHP HLCTNASSFS GTGVNNTPEE
LREKLVNKMK LVLSSGSDEE CAVCLDSLTF PVITHCAHVF CKPCICEVIQ SEQPNAKCPL
CRNELRLEHL IECPPEESDF ESVKKSDREW IPSSKINALM HALIELRKEN PVVKCLIVSQ
FTTFLSLIET PLRESGFVFT RLDGSMPQKK RVEAIQCFQS SQAGSPTIML LSLKAGGVGL
NLTAASRVFL MDPAWNPAAE DQCFDRCHRL GQKQAVIITK FVVKNSVEEN MLSIQNKKRK
LAAGAFATKK PTASEVKQTK INEIKTLIDL
//
