ID A0A151NF84_ALLMI Unreviewed; 614 AA.
AC A0A151NF84;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Leukocyte elastase inhibitor isoform B {ECO:0000313|EMBL:KYO35472.1};
GN Name=SERPINB1 {ECO:0000313|EMBL:KYO35472.1};
GN ORFNames=Y1Q_0008039 {ECO:0000313|EMBL:KYO35472.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO35472.1};
RN [1] {ECO:0000313|EMBL:KYO35472.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO35472.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- SIMILARITY: Belongs to the serpin family.
CC {ECO:0000256|RuleBase:RU000411}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO35472.1}.
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DR EMBL; AKHW03003201; KYO35472.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A151NF84; -.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR Gene3D; 2.30.39.10; Alpha-1-antitrypsin, domain 1; 2.
DR Gene3D; 3.30.497.10; Antithrombin, subunit I, domain 2; 2.
DR InterPro; IPR023796; Serpin_dom.
DR InterPro; IPR000215; Serpin_fam.
DR InterPro; IPR036186; Serpin_sf.
DR InterPro; IPR042178; Serpin_sf_1.
DR InterPro; IPR042185; Serpin_sf_2.
DR PANTHER; PTHR11461:SF180; LEUKOCYTE ELASTASE INHIBITOR; 1.
DR PANTHER; PTHR11461; SERINE PROTEASE INHIBITOR, SERPIN; 1.
DR Pfam; PF00079; Serpin; 2.
DR SMART; SM00093; SERPIN; 2.
DR SUPFAM; SSF56574; Serpins; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000050525}.
FT DOMAIN 1..287
FT /note="Serpin"
FT /evidence="ECO:0000259|SMART:SM00093"
FT DOMAIN 305..614
FT /note="Serpin"
FT /evidence="ECO:0000259|SMART:SM00093"
SQ SEQUENCE 614 AA; 70471 MW; AF8A7F338DA95CE4 CRC64;
MKQVLCLSKA EDIHKSYQPL VSEINKPGTK YTLRTANQLY AEKTHEFLAS FTESCQKFYH
AALEQVDFSN APEDSRKHIN AWVEKKTEGK IQDLLAQGII NSLTKLVLVN AIYFKGNWET
QFCKDHTKEK PFKINKNESK PVQMMFRKAK FNMTCIREFQ TKILELPYID NELSMIILLP
DNIEDETTGL EKLERELSYE KLMDWINPEM MDYTEVEVSL PRFKLEENYD LKTLLSSMGM
PDAFDQNKAD LSGMAGNKDL YLSQVVHNLP LIPGSLPGVH SARHLRPVVL VTMEKLRNAN
TCFALALLKK LNETNPTGNI FFSPISISAA LAMILLGAKG NTKTQMLKAL HYDDAEDLHS
RFQTLTSDVN RQGAPYLLKL ANRLYGEKTC IFLPDFLANT QKSYGASLAM VDFLHASDEA
RKHINQWVEE QTEGKIPNLL SEGLLNNTTR LVLVNAIYFK GKWGEKFEEQ NTKEMPFHLN
KNETKTVKMM YQKKKFPFGY ICELECRVLE LPYDGDELSM IILLPDEIKD DTTGLQQLEK
QLTFEKLCEW TKLQNMQPID VHVHLPKFKL EDSYDLKSAL SGRQAVIHHA YNKLMDLMSL
VQDVASQQLS NCQH
//
