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Database: UniProt
Entry: A0A151NIU3_ALLMI
LinkDB: A0A151NIU3_ALLMI
Original site: A0A151NIU3_ALLMI 
ID   A0A151NIU3_ALLMI        Unreviewed;       420 AA.
AC   A0A151NIU3;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   31-JUL-2019, entry version 20.
DE   SubName: Full=ATP-sensitive inward rectifier potassium channel 11 {ECO:0000313|EMBL:KYO36723.1};
GN   Name=KCNJ11 {ECO:0000313|EMBL:KYO36723.1};
GN   ORFNames=Y1Q_0024385 {ECO:0000313|EMBL:KYO36723.1};
OS   Alligator mississippiensis (American alligator).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC   Alligator.
OX   NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO36723.1};
RN   [1] {ECO:0000313|EMBL:KYO36723.1, ECO:0000313|Proteomes:UP000050525}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO36723.1};
RX   PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA   St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y.,
RA   Gongora J., Dalzell P., Moran C., Bed'hom B., Abzhanov A.,
RA   Burgess S.C., Cooksey A.M., Castoe T.A., Crawford N.G., Densmore L.D.,
RA   Drew J.C., Edwards S.V., Faircloth B.C., Fujita M.K., Greenwold M.J.,
RA   Hoffmann F.G., Howard J.M., Iguchi T., Janes D.E., Khan S.Y.,
RA   Kohno S., de Koning A.J., Lance S.L., McCarthy F.M., McCormack J.E.,
RA   Merchant M.E., Peterson D.G., Pollock D.D., Pourmand N., Raney B.J.,
RA   Roessler K.A., Sanford J.R., Sawyer R.H., Schmidt C.J., Triplett E.W.,
RA   Tuberville T.D., Venegas-Anaya M., Howard J.T., Jarvis E.D.,
RA   Guillette L.J.Jr., Glenn T.C., Green R.E., Ray D.A.;
RT   "Sequencing three crocodilian genomes to illuminate the evolution of
RT   archosaurs and amniotes.";
RL   Genome Biol. 13:415-415(2012).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC   -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel
CC       (TC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822,
CC       ECO:0000256|SAAS:SAAS00549381}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KYO36723.1}.
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DR   EMBL; AKHW03002956; KYO36723.1; -; Genomic_DNA.
DR   RefSeq; XP_006263861.1; XM_006263799.3.
DR   RefSeq; XP_014465235.1; XM_014609749.2.
DR   RefSeq; XP_019345119.1; XM_019489574.1.
DR   RefSeq; XP_019345120.1; XM_019489575.1.
DR   STRING; 8496.XP_006263861.1; -.
DR   GeneID; 106737283; -.
DR   KEGG; amj:106737283; -.
DR   CTD; 3764; -.
DR   KO; K05001; -.
DR   OrthoDB; 956263at2759; -.
DR   PhylomeDB; A0A151NIU3; -.
DR   Proteomes; UP000050525; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015272; F:ATP-activated inward rectifier potassium channel activity; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1400; -; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR041647; IRK_C.
DR   InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR   InterPro; IPR003278; K_chnl_inward-rec_Kir6.1.
DR   InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR   InterPro; IPR040445; Kir_TM.
DR   PANTHER; PTHR11767; PTHR11767; 1.
DR   PANTHER; PTHR11767:SF11; PTHR11767:SF11; 1.
DR   Pfam; PF01007; IRK; 1.
DR   Pfam; PF17655; IRK_C; 1.
DR   PIRSF; PIRSF005465; GIRK_kir; 1.
DR   PRINTS; PR01331; KIR61CHANNEL.
DR   PRINTS; PR01320; KIRCHANNEL.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000050525};
KW   Ion channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434609, ECO:0000313|EMBL:KYO36723.1};
KW   Ion transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434639};
KW   Membrane {ECO:0000256|SAAS:SAAS00434581, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434575};
KW   Potassium transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434641};
KW   Reference proteome {ECO:0000313|Proteomes:UP000050525};
KW   Transmembrane {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434543, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00036756,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00036755};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00048561}.
FT   TRANSMEM     73     94       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    151    174       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       37    179       IRK. {ECO:0000259|Pfam:PF01007}.
FT   DOMAIN      187    357       IRK_C. {ECO:0000259|Pfam:PF17655}.
FT   REGION      371    420       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS    386    420       Polar. {ECO:0000256|SAM:MobiDB-lite}.
FT   SITE        166    166       Role in the control of polyamine-mediated
FT                                channel gating and in the blocking by
FT                                intracellular magnesium.
FT                                {ECO:0000256|PIRSR:PIRSR005465-1}.
SQ   SEQUENCE   420 AA;  47483 MW;  2AB3361B6805101B CRC64;
     MLARKSIIPE EYVLARIAAE NLRKPRVRDR PRKARFIAKN GACNLAHKNI REQGRFLQDI
     FTTLVDLKWR HTLVIFTMSF LCSWLLFAMV WWLVAFAHGD MDRIDNSKGS ANWTPCVTDV
     GSFTSAFLFS IEVQVTIGFG GRMMTEECPT AITVLILQNI VGLIINAVML GCIFMKTAQA
     HRRAETLIFS RHAVIAVRNG RLCFMFRVGD LRKSMIISAS VRIQAVKKTT TPEGEIIPIH
     QLDIPVDNPI ESNNIFLVAP LIICHIIDKR SPLYDISPSD LVNQDLELIV ILEGVVETTG
     ITTQARTSYI AEEILWGHRF VPIVTEEEGV YAVDYSKFGN TIKVAAPRCS ARELDEKPSI
     LIQTLQKSEL SHQNSLRKRN SMRRNNSIRR NNSMRRTNSS LMVPKVQFIT PEGNQSASET
//
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