ID A0A151NN37_ALLMI Unreviewed; 808 AA.
AC A0A151NN37;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KYO38194.1};
GN ORFNames=Y1Q_0016034 {ECO:0000313|EMBL:KYO38194.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO38194.1};
RN [1] {ECO:0000313|EMBL:KYO38194.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO38194.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479,
CC ECO:0000256|RuleBase:RU003762}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004479, ECO:0000256|RuleBase:RU003762}.
CC -!- SIMILARITY: Belongs to the integrin alpha chain family.
CC {ECO:0000256|ARBA:ARBA00008054, ECO:0000256|RuleBase:RU003762}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO38194.1}.
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DR EMBL; AKHW03002526; KYO38194.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A151NN37; -.
DR STRING; 8496.A0A151NN37; -.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR GO; GO:0008305; C:integrin complex; IEA:InterPro.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR Gene3D; 2.130.10.130; Integrin alpha, N-terminal; 1.
DR Gene3D; 2.60.40.1460; Integrin domains. Chain A, domain 2; 1.
DR Gene3D; 2.60.40.1510; ntegrin, alpha v. Chain A, domain 3; 1.
DR InterPro; IPR013517; FG-GAP.
DR InterPro; IPR013519; Int_alpha_beta-p.
DR InterPro; IPR000413; Integrin_alpha.
DR InterPro; IPR013649; Integrin_alpha_Ig-like_1.
DR InterPro; IPR048285; Integrin_alpha_Ig-like_2.
DR InterPro; IPR028994; Integrin_alpha_N.
DR InterPro; IPR032695; Integrin_dom_sf.
DR PANTHER; PTHR23220; INTEGRIN ALPHA; 1.
DR PANTHER; PTHR23220:SF90; INTEGRIN ALPHA-7; 1.
DR Pfam; PF01839; FG-GAP; 2.
DR Pfam; PF08441; Integrin_A_Ig_1; 1.
DR Pfam; PF20805; Integrin_A_Ig_2; 1.
DR PRINTS; PR01185; INTEGRINA.
DR SMART; SM00191; Int_alpha; 5.
DR SUPFAM; SSF69318; Integrin alpha N-terminal domain; 1.
DR SUPFAM; SSF69179; Integrin domains; 2.
DR PROSITE; PS51470; FG_GAP; 4.
PE 3: Inferred from homology;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889,
KW ECO:0000256|RuleBase:RU003762};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Integrin {ECO:0000256|ARBA:ARBA00023037, ECO:0000256|RuleBase:RU003762};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|RuleBase:RU003762};
KW Reference proteome {ECO:0000313|Proteomes:UP000050525};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|RuleBase:RU003762};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|RuleBase:RU003762"
FT CHAIN 26..808
FT /evidence="ECO:0000256|RuleBase:RU003762"
FT /id="PRO_5007358861"
FT REPEAT 267..323
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT REPEAT 324..385
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT REPEAT 386..441
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT REPEAT 445..504
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT DOMAIN 489..652
FT /note="Integrin alpha first immunoglubulin-like"
FT /evidence="ECO:0000259|Pfam:PF08441"
FT DOMAIN 655..808
FT /note="Integrin alpha second immunoglobulin-like"
FT /evidence="ECO:0000259|Pfam:PF20805"
SQ SEQUENCE 808 AA; 87185 MW; FE2B614E30212998 CRC64;
MCPRRVRAPI HDAAWGLVAL ALVQGEVALG SPWGSDVAPS PCRLLVGAPQ APAFPGQGAN
RTGGLYACPL TREPDDCWRV PIDQGADLQR ESKENQWLGV SVRSQGPGGK IVACAHLYEA
RHRVGQELET RDAVGRCFLL SQDLAERDEL DGGDWTFCQG RPQGHDRFGL CQQGLAAGFS
PDRRYVLFGA PGTYNWKGTV RVERCNQSTL DLGLLDDGPY EAGGEKEQDP SRIPLPANSY
LGLLFVTNVD SSDPDQLVYK TLEPSEQGPG ASADVAQNSY LGFSLDSGKG LTRAQELSFV
AGAPRANHTG AVVLLRRDAL NRLVPEALLP GEQLTSAFGY ALALADLNSD GWLDLVVGAP
HFFDRHQELG GAAYVYINPS GRWEGARPLR LNGPPGSMFG VTVGALGDLN QDGFEDVAVG
APFDGAGKVY IYHGSSLGIV TKPAQVLDGE AVGMTTFGYS LSGGLDVDGN AYPDLLVGSL
ADTVALYRAR PVIHVSRSIT LEPPNIDLER ETCRGHPGIC VDVRLCFSYT ATPTSYSPHV
TLEYLLEADA DRRQLGRMPR VAFPQRRPTD PEHRLSGEVE LPGQRARVCV DSTFQLQDNI
RDKLRPIAVV LSYDIKLARS KRQAPGAALP PLPPVLSAQQ PSIQRAQVHF LRQGCGEDKV
CQSNLQLEAW FCSRTGDADF LPLPSEADGT AMFAMTDQKD VALEIHVTNM PSDPAEPQRD
GDDAHEALLT ATFPSALLYA SARPYDARAP PGMEKPVLCQ SNENGSQAEC DLGNPMKRGA
QVRFYLIVST SGITLETTEL EVQLQLST
//
