ID A0A151NTM5_ALLMI Unreviewed; 2167 AA.
AC A0A151NTM5;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Putative cation-transporting ATPase 13A2 isoform B {ECO:0000313|EMBL:KYO40010.1};
GN Name=ATP13A2 {ECO:0000313|EMBL:KYO40010.1};
GN ORFNames=Y1Q_0012966 {ECO:0000313|EMBL:KYO40010.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO40010.1};
RN [1] {ECO:0000313|EMBL:KYO40010.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO40010.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the cation transport ATPase (P-type) (TC 3.A.3)
CC family. Type V subfamily. {ECO:0000256|ARBA:ARBA00006000}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO40010.1}.
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DR EMBL; AKHW03002106; KYO40010.1; -; Genomic_DNA.
DR STRING; 8496.A0A151NTM5; -.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0019829; F:ATPase-coupled monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0015662; F:P-type ion transporter activity; IEA:InterPro.
DR CDD; cd07542; P-type_ATPase_cation; 1.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 2.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 2.
DR Gene3D; 1.20.1110.10; Calcium-transporting ATPase, transmembrane domain; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 2.
DR InterPro; IPR004014; ATPase_P-typ_cation-transptr_N.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR018303; ATPase_P-typ_P_site.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR006544; P-type_TPase_V.
DR InterPro; IPR047821; P5B-type_ATPase.
DR InterPro; IPR001757; P_typ_ATPase.
DR InterPro; IPR044492; P_typ_ATPase_HD_dom.
DR NCBIfam; TIGR01494; ATPase_P-type; 2.
DR NCBIfam; TIGR01657; P-ATPase-V; 2.
DR PANTHER; PTHR45630:SF4; CATION-TRANSPORTING ATPASE 13A5-RELATED; 1.
DR PANTHER; PTHR45630; CATION-TRANSPORTING ATPASE-RELATED; 1.
DR Pfam; PF13246; Cation_ATPase; 2.
DR Pfam; PF00690; Cation_ATPase_N; 2.
DR Pfam; PF00122; E1-E2_ATPase; 2.
DR PRINTS; PR00119; CATATPASE.
DR SFLD; SFLDS00003; Haloacid_Dehalogenase; 1.
DR SFLD; SFLDF00027; p-type_atpase; 1.
DR SMART; SM00831; Cation_ATPase_N; 1.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 2.
DR SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 3.
DR SUPFAM; SSF56784; HAD-like; 2.
DR SUPFAM; SSF81660; Metal cation-transporting ATPase, ATP-binding domain N; 2.
DR PROSITE; PS00154; ATPASE_E1_E2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000050525};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 53..79
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 426..450
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 462..484
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 894..912
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 918..937
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 958..980
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1034..1052
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1064..1084
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1104..1121
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1245..1262
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1268..1287
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1444..1465
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1882..1904
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1950..1972
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2015..2032
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2044..2064
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2084..2105
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 177..250
FT /note="Cation-transporting P-type ATPase N-terminal"
FT /evidence="ECO:0000259|SMART:SM00831"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2167 AA; 239708 MW; 87E175938A17E2C4 CRC64;
MPSMEPRQGV PGERSSCQPR GQKGGCRLRK QSVKLHNLVE EHNRVQQSAS DTITMALLLL
TVPVPPAIPA ALTTAIVYAQ RRLKQKQIFC ISPQRINICG QINLVCFEKD EFHLYSRKVV
TWISVSALPS FKPGHPLVAD ESSVINEALM KPDLKVRCIQ VQKIRYLWNI SGKRFQKIGC
LEDHHTCSDM HDKFGSGLSH EDQAIRRLIC GPNTIDVRVV PIWKLLVKEV LHPFYVFQLF
SICLWFADDY MEYASAILLM SLLSVSLTVY DLRKQSVKLH RLVESHTNVT VTVFRKMEGC
QKVKSHQLVP GDTLVLTEGK SFLPCDAVLI SGRCIVNESM LTGESIPVTK APLPYANNAE
PWKTHCSEEY KRHILFCGTE VIQTKADGEG LVKAIVLQTG FNTAKGDLVR SILYPKPINF
KLYRDAMSFL MCLIALATAG MIYTVCIFAL NGEEPGDIVK KALDIITIAV PPALPAALTT
GIIYTQRRLK NKGIFCISPQ RINMCGQLNL FCFDKTGTLT EDGLDLLGVV PAEGNRFQEV
HSFASGQTLP WGPVCGAMVS CHSLVLLEGR TQGDPLDLKM FEATGWELEE SGGDHAAGGG
SVHTTMIKPG PKAGQVPVRG MAILHHFPFT SALRRMSVIA QEIGGAQHVF MKGAPETVAE
FCRPETVPSQ LTSELQLYTA QGFRVIGLAH RVLQAGNQTA RLIRKDVESG LVFLGLLIME
NRLKRETKPV LEELSAACIR NVMVTGDNIQ TAVTVAKNAS MISPTSQVIL VEAKELPGTP
AASVTWTLME GSHLNGSKGL LLLNGTVFAR MSPGQKSSLV EEFQKLGYYV GMCGDGANDC
GALKVAHAGI SLSEEEASVA SPFTTRTPTI ECVPQLIREG RAALVTSLCM FKYMALYSII
QYLGVLLLYW QLNSFGNYQF LFQDLAINTV IGVTMSLNGA YPKLVPYRPP SQLVSPPLLL
SLVLHILFSL GLQICGFLVV QEQPWYSKED ISSACLSGKT SLANHSSSSS SLNGMGNATL
GQEVDNGFKS YENSTVWLLS TINCIAVALV VSKGKPFRQP AYTNYQFVLA LTVQLGVCIF
LMFADMEGVY SIFDLVCTPP VWRVSMLIML AITFAASLLV EDEFQRYTRK KVTWTDLSTL
TVSVSDKPDG LLIADKDSII NRAIMKPELK VRCIQVQKIR YIWDISAKQF HKVGSLEDSN
SCNDMHQKFG AGLTREEQNI RRLVCGPNAI EIEIRPIWKL LFKEILNPFY VFQAFTLTLW
ITQGYVEYSV AIIILSIISI SLTVFDLRQQ SVKLHNLVEE HNRVQVKACT KDEGCKTLES
HLLVPGDVLV LEGKKLSLPC DAVLIDGGCI VNEGMLTGES IPVTKTALPH ADNTMPWKTH
SVEDYRRHVL FCGTEVIQTK PSGRGPVRAV VLQTGFNTAK GDLVRSILYP KPVNFKLYRD
AFKFIVGLAV IGVLGLIYTV CVYAYRKTGT LTEDGLDLWG VIPSEGSRFQ NVHSFTSGAP
LPWGPVCGAM ASCHSLALLD GKIQGDPLDL KMFEGTNWEM EDPSDTEGLD SCIVIKPGPN
ASNAPVEGIV ILHQFPFSSA LQRMAVVTQE VGKNQYDLYM KGAPEMVASF CRPETVPTDF
VKELQVYTTQ GFRVIALAHK ALNVGKDVAV DSLEREDVES GLAFLGLLIM ENRLKRETKP
VLEELSAARI RSVMVTGDNL QTAVTVAKNS EMIPKSSPVI LIEANEPEGT TPASITWQLM
EESKQATAET NEVYVDIETR TPPDRDVHSH HFAMNGKSYQ VIVKHFSSLL PKILVNGTVF
ARMSPNQKSS LVEEFQNLNY YVGMCGDGAN DCGALKAAHA GISLSEQEAS VASPFTSQIP
NIECVPELIR EGRAALVASF AVFKYLTLYG LIQFIGTSLL FWQLQIFGNY QYLIEDVGIT
LLVCLTMSLT HAYPKLAPYR PPGQLISPPL LLSIVLNVCF TTTILFGGFL LVKQQPWYSE
TPNPRGCPQP LAPVSTATTN ATHVSSSVLS YEGTTMWPLA TINCIIIAFV FSKGKPFRKP
IYTNYIFSLF LLLQLGICIF ILFADIDAVY RGMELLCTPT MWRVYILITA LVTFCVSFVV
EDLVLQNRRL WLLIKKCFGF RSKSQYRKWQ RKLATDPTWP PLQRTDFAEN GKNEIYTNPA
YEHSEEK
//
