ID A0A151NVK4_ALLMI Unreviewed; 864 AA.
AC A0A151NVK4;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Zinc finger protein 282 isoform A {ECO:0000313|EMBL:KYO40907.1};
GN Name=ZNF282 {ECO:0000313|EMBL:KYO40907.1};
GN ORFNames=Y1Q_0020487 {ECO:0000313|EMBL:KYO40907.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO40907.1};
RN [1] {ECO:0000313|EMBL:KYO40907.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO40907.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO40907.1}.
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DR EMBL; AKHW03001812; KYO40907.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A151NVK4; -.
DR eggNOG; KOG1721; Eukaryota.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd07765; KRAB_A-box; 1.
DR Gene3D; 6.10.140.140; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 9.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR036051; KRAB_dom_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR23232; KRAB DOMAIN C2H2 ZINC FINGER; 1.
DR PANTHER; PTHR23232:SF121; ZINC FINGER PROTEIN 282; 1.
DR Pfam; PF01352; KRAB; 1.
DR Pfam; PF00096; zf-C2H2; 7.
DR SMART; SM00349; KRAB; 1.
DR SMART; SM00355; ZnF_C2H2; 9.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 5.
DR SUPFAM; SSF109640; KRAB domain (Kruppel-associated box); 1.
DR PROSITE; PS50805; KRAB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 8.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 9.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000050525};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 147..218
FT /note="KRAB"
FT /evidence="ECO:0000259|PROSITE:PS50805"
FT DOMAIN 388..415
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 416..443
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 444..471
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 472..495
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 694..721
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 722..749
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 750..777
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 778..805
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 806..833
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 498..672
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 820..854
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 511..531
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 541..555
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 820..834
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 864 AA; 95557 MW; E3C86C8ABC1E03D2 CRC64;
MAEWAPAQVQ VQEWNVEAQH LMALQPPLLP ERAHVREAQL HTAEASLWTV VATVQALERK
IDVLAARLLS LEGRSGTAEK KIVDCEKTAM EFNNQLESKW AVLGTLIQEY GLLQRRLENM
ENLLKNRNFW VLRLPPGAKG EVPKMPVTFV DVAVYFSAEE WKNLEEWQKE LYNNLVKENY
ESLISLGSSL SKADAQPRPE RGVEPCIPQQ PELEQRPIPV DHCPDPLVST PDILSRIKQE
AAFVAEHQFP EDRGLPPDPC AGADALISAH DFLSWIKQEE EPCVREPWEL AEREILTGPV
PGNGLMVKAE EMRHRQEAPC DLGLPPGTCG DALFPGSAYA SQEAPGLPPA PPAECRLGKS
LPLASGTSEF PGTPAARGTG AAGVERPHSC NECGKTFSVK KSLRIHQRSH AKERPYECTE
CGRSFNCHSG LVRHQMIHRG ERPYQCGDCG KRYSRKEHLQ NHQRLHTGER PFQCAACGKS
FIRKQNLLKH QRIHTDGAIP KPCLLPWTES REEPRVGDRG GLAERETENT ARPRTAGVPS
QREPGEEERA GNPQHPQERD VSALGAGGPE VVVKVEEQSP DERPAGNEQA GVPSGETASR
SLQGREAGDR LAPEDRGESL QRPVLPPRPA DPKTSRGAEP GPVGTSWSCG DAGEPRPSAP
AASAPPAGKP PACTQCGKST PLLHQSPHGP AKPHQCSQCS QSFHHSSRLN SHSRAHSGER
PYTCAQCGKG YGRKEHLQNH QRLHTGERPF PCAQCGKRYS RKEYLQNHQR LHTGERPYVC
PACGKSFICK QSLLKHQRVQ CGERPYQCGD CGRSFRYKES LKEHQREHGA QPREHGTQPR
QPAPSPGRGS EAEVVCVKVE LEDE
//
