ID A0A151NVM3_ALLMI Unreviewed; 829 AA.
AC A0A151NVM3;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=Rho GTPase-activating protein 17 isoform B {ECO:0000313|EMBL:KYO40814.1};
GN Name=ARHGAP17 {ECO:0000313|EMBL:KYO40814.1};
GN ORFNames=Y1Q_0013383 {ECO:0000313|EMBL:KYO40814.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO40814.1};
RN [1] {ECO:0000313|EMBL:KYO40814.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO40814.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO40814.1}.
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DR EMBL; AKHW03001857; KYO40814.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A151NVM3; -.
DR STRING; 8496.A0A151NVM3; -.
DR eggNOG; KOG4270; Eukaryota.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd07619; BAR_Rich2; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR004148; BAR_dom.
DR InterPro; IPR047165; RHG17/44/SH3BP1-like.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR14130; 3BP-1 RELATED RHOGAP; 1.
DR PANTHER; PTHR14130:SF13; RHO GTPASE-ACTIVATING PROTEIN 44; 1.
DR Pfam; PF03114; BAR; 2.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00721; BAR; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 2.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS51021; BAR; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000050525}.
FT DOMAIN 14..276
FT /note="BAR"
FT /evidence="ECO:0000259|PROSITE:PS51021"
FT DOMAIN 282..472
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 491..521
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 555..619
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 674..723
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 809..829
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 503..517
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 562..577
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 582..619
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 675..720
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 829 AA; 92240 MW; 55383EB7433153FA CRC64;
MKKQFHRMRQ LANQTVGRAE KTEVLSEDLL QVEKRLELVK QVSHSTHKKL TACLQGQQGV
DADKRSKKLP LTTLAQCLME GSAILGDDSL LGKMLKLCGE AEDKLAQELI NFELQVERDV
IEPLFVLAEV EIPNIQKQRK HLAKLVLDMD SSRTRWQQSA KSSGLSSNLQ PSGAKADALR
EEMEEAANRV EICRANKGHI QGTTDHPKIA NWRGSDAELL KDQLSADMYN FVAKEIDYAN
YFETLIEVQA EYHRKSLALL QNVLPQIKAQ QEAWIEKPSF GKPLEEHLAV SGREIAFPIE
ACVTMLLECG MQEEGLFRVA PSASKLKKLK AALDCCVVDV QEYSADPHAI AGALKSYLRE
LPEPLMTFEL YEEWIQASNI QDQDKRLQAL WNACEKLPKT NYNNIRYLIK FLAKLTEYQD
ANKMTPSNVA IVLGPNLLWP QAEGNITEMM TTVSLQIVGI IEPLIQHADW FFPGDIEFNV
TGNYGSPMHV NHNANYSSMP SPDMDHSDRK QHDQARRPLS VATDNMMLEF YKKDGMGVRV
MDTSWVARRG TSIVRKASST PPAMQPPAPP SDLPAAPQSP IPEQSLDISA TPPPTPTSFG
FQPGAERTST DDVSSSWSDS CYNYPSPEDD RPSPFPCYRH LHHFYPKARP EALSPPYRWS
GCTCARDRGA GLSSTLKTKE LSPVSGQQKG SPGSSSMAPC GSTQQAAGPT QQLSTEQSPH
TLRKVSKKLA PIPPKVPYGQ SGVLSLWSTP CLMACPPGKA CPQLFEASDA ILDRCEGDFQ
DLVHFDIPSI HIEIDTALHR DPLEHIQRHS VTRKGDLEEE EEESESTAL
//
