ID A0A151NWL1_ALLMI Unreviewed; 932 AA.
AC A0A151NWL1;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE SubName: Full=Mucin-16 {ECO:0000313|EMBL:KYO41154.1};
GN Name=MUC16 {ECO:0000313|EMBL:KYO41154.1};
GN ORFNames=Y1Q_0011872 {ECO:0000313|EMBL:KYO41154.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO41154.1};
RN [1] {ECO:0000313|EMBL:KYO41154.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO41154.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO41154.1}.
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DR EMBL; AKHW03001665; KYO41154.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A151NWL1; -.
DR STRING; 8496.A0A151NWL1; -.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.30.70.960; SEA domain; 7.
DR InterPro; IPR028850; MUC16.
DR InterPro; IPR000082; SEA_dom.
DR InterPro; IPR036364; SEA_dom_sf.
DR PANTHER; PTHR14672; MUCIN-16; 1.
DR PANTHER; PTHR14672:SF1; MUCIN-16; 1.
DR Pfam; PF01390; SEA; 6.
DR SMART; SM00200; SEA; 4.
DR SUPFAM; SSF82671; SEA domain; 7.
DR PROSITE; PS50024; SEA; 7.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000050525};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 880..905
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..68
FT /note="SEA"
FT /evidence="ECO:0000259|PROSITE:PS50024"
FT DOMAIN 76..197
FT /note="SEA"
FT /evidence="ECO:0000259|PROSITE:PS50024"
FT DOMAIN 205..326
FT /note="SEA"
FT /evidence="ECO:0000259|PROSITE:PS50024"
FT DOMAIN 344..465
FT /note="SEA"
FT /evidence="ECO:0000259|PROSITE:PS50024"
FT DOMAIN 480..601
FT /note="SEA"
FT /evidence="ECO:0000259|PROSITE:PS50024"
FT DOMAIN 613..728
FT /note="SEA"
FT /evidence="ECO:0000259|PROSITE:PS50024"
FT DOMAIN 740..862
FT /note="SEA"
FT /evidence="ECO:0000259|PROSITE:PS50024"
SQ SEQUENCE 932 AA; 105448 MW; 11658C73BEE0A539 CRC64;
MAFRRDLETG TRNDIHVDAV CTYRRDSTSL KFDRVKVYQE LSNKTEGITR LGPYNLNNTS
LYVNAVRPAT IPIPVKDERF TVNFTITNLL YSSEFQNPSS SKYNATRNTL AHMLDLLLKN
SSIGPTHTGC TVVALRSVKN SDDTGVDAVC TYRHNPTASQ FDTVKIYHEL SNMTRGSTKL
GPYTLDNNSL YVNAVNPDKE TPLPRPEHST LNFTLTNLRF TVDLGKLSSP KFSSTEKIMC
HYIGLLLQKS SIGTDYIGCK VVAFRSVKNR DNTGVDAIFS YRNDPTAPRF DRMKVYRELR
NMTDGITKLG FYTLDRKSLY VNGYNELSTS PPVIPPTTKS PTPTTQQFTL NFTITNLRFT
PDLGRPGSPK FSTTEKIMRH FIEPLLQNNS TGPNYLGCKV DAFRPVKNRD NTAVDATCSY
RNDPAARQFD RVKVYRKLSS MTKDITKLGH YSLDNRSLYV NGYNEVPGLY PSLTTRQSPM
AGHFTLNLTL TNLRYTADLG VPGTQKFNST QSMMKYYMDS LLRDSSIGPI YTGCKVMAFR
SVRNSDDTGV DTLCSYKNNP SVAKFNKVEI YHELKSKTKG VTKLGIYTLE KNSLYVDGFH
LSETATNNNP MPVAVGYQLG FKIINEKLTN PDPASSEYQK LLRDIQQKVN NMYHQSAVQD
KFQYCNVTGL RIGSVVVDCH CFFKPAPNIS NAVVERAFQD GTRNATANWL GASYQLQGIS
VDVLVTDSIT GSYNLPSKYE KENFKLNFSI TNLPYSPEMN DPNSLRHQSN KQQIEKELQD
IFRKSTLKNY FIGCTVQNFR LISGKSYTGV DSTCVFTLDP YTRAFRKEDV YEEFKQLTHG
LTELGSSYKL DTNSLFVNNY SPLNTMAGDA NNSELSYWEI ILICLAVLIG FILLLFLGFL
IAFCLQRKGN MYEVQQGMYG IYFPHLDWRK MH
//
