ID A0A151NXP6_ALLMI Unreviewed; 427 AA.
AC A0A151NXP6;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Guanine nucleotide exchange factor for Rab-3A isoform A {ECO:0000313|EMBL:KYO41637.1};
GN Name=RAB3IL1-1 {ECO:0000313|EMBL:KYO41637.1};
GN ORFNames=Y1Q_0006385 {ECO:0000313|EMBL:KYO41637.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO41637.1};
RN [1] {ECO:0000313|EMBL:KYO41637.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO41637.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- SIMILARITY: Belongs to the SEC2 family.
CC {ECO:0000256|ARBA:ARBA00025794}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO41637.1}.
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DR EMBL; AKHW03001628; KYO41637.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A151NXP6; -.
DR eggNOG; KOG4324; Eukaryota.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR CDD; cd21069; Rab11BD_RAB3IL1; 1.
DR Gene3D; 1.20.5.4880; -; 1.
DR InterPro; IPR040351; RAB3IL/RAB3IP/Sec2.
DR InterPro; IPR009449; Sec2_N.
DR PANTHER; PTHR14430:SF5; GUANINE NUCLEOTIDE EXCHANGE FACTOR FOR RAB-3A; 1.
DR PANTHER; PTHR14430; RABIN3-RELATED; 1.
DR Pfam; PF06428; Sec2p; 1.
DR SUPFAM; SSF144284; Sec2 N-terminal region; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000050525}.
FT DOMAIN 139..198
FT /note="GDP/GTP exchange factor Sec2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF06428"
FT REGION 211..252
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 122..206
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 236..252
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 427 AA; 47700 MW; 81A8836DA3BB2CEF CRC64;
MDAGTTVYNL SAFDYPSGAK AREGTAETWN AGVLMCECPV EASQDGEGPS AVGSQAQFEE
GGQKQQVVGQ WKPLVPSKGG KELLESKPCC LDAGGGDETQ STAQLNVSRL RSSSVEIREK
GSEFLKEELH KAQKELKLKD EECERLSKVR EQLEQELEEL TASLFEEAHK MVREANTKQA
ASEKQMREAR GKIDMLQAEV TALKTLVITS TPSSPNRELH PQLQSPTKAV FRKGHGRNKS
TSSAVSTASG QSLPLEPVNH EYKEVDAILF AEFQAWKEAP TLDKACSFLE RIYREDVEPC
LDFTRHELSE LVRAAVEQNT LTIEPVASQV LPVVKVSTIE CGRPKKCALS GLSRTCKHRI
KLGDSGNYYY ISPSCRARIT AVCNFFTYIR YIQQGLVRQD VELMYWEIMR LRREMSMAKL
GFYPNEM
//
