ID A0A151NYQ4_ALLMI Unreviewed; 976 AA.
AC A0A151NYQ4;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Transcription initiation factor TFIID subunit 4 {ECO:0000313|EMBL:KYO42002.1};
GN Name=TAF4 {ECO:0000313|EMBL:KYO42002.1};
GN ORFNames=Y1Q_0002656 {ECO:0000313|EMBL:KYO42002.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO42002.1};
RN [1] {ECO:0000313|EMBL:KYO42002.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO42002.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the TAF4 family.
CC {ECO:0000256|ARBA:ARBA00006178}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO42002.1}.
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DR EMBL; AKHW03001485; KYO42002.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A151NYQ4; -.
DR STRING; 8496.A0A151NYQ4; -.
DR eggNOG; KOG2341; Eukaryota.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR GO; GO:0005669; C:transcription factor TFIID complex; IEA:InterPro.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR GO; GO:0006366; P:transcription by RNA polymerase II; IEA:UniProt.
DR CDD; cd08045; TAF4; 1.
DR Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR Gene3D; 1.20.120.1110; TAFH/NHR1 domain; 1.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR045144; TAF4.
DR InterPro; IPR007900; TAF4_C.
DR InterPro; IPR037249; TAFH/NHR1_dom_sf.
DR InterPro; IPR003894; TAFH_NHR1.
DR PANTHER; PTHR15138; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4; 1.
DR PANTHER; PTHR15138:SF18; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4; 1.
DR Pfam; PF05236; TAF4; 1.
DR Pfam; PF07531; TAFH; 1.
DR SMART; SM00549; TAFH; 1.
DR SUPFAM; SSF47113; Histone-fold; 1.
DR SUPFAM; SSF158553; TAFH domain-like; 1.
DR PROSITE; PS51119; TAFH; 1.
PE 3: Inferred from homology;
KW Initiation factor {ECO:0000313|EMBL:KYO42002.1};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Protein biosynthesis {ECO:0000313|EMBL:KYO42002.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000050525};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 520..617
FT /note="TAFH"
FT /evidence="ECO:0000259|PROSITE:PS51119"
FT REGION 1..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 405..428
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 896..976
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 20..39
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 896..918
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 976 AA; 101129 MW; B80E547263CD8A50 CRC64;
MGLSAPEVPK AGAGGVQGGV INHNTRSQSS ALDGATTTST STTTAAATAA AAGGGGGSEV
TAAPGTLSQG KSVVISTMAT SLSTRNGKIG TTTVQTLNGS NVVMNSHHSG SAAFSGTPAT
ANPASAPAVA PLVNNGPGSV GKANTVNAVL PSASSTVIQT SFLSTAVSSA SSSPTVISSQ
PPPSIGSGGA TVALVRPPIH TAGPTVAAAA AATQNGSNTV INSTISVGNF PAVAAATVGS
GVALQTSLVN SQPGSSVPAA PTTQVIKSES PKTIVQAVSQ QQTLAASGQP STTGGNMIIG
QTMQAGLSNV APNPGGIPPA APGTPTGMAK GTANTVAQNL PRTPAATTSG IRATLTPTVL
APRLPQPPQN PTNIQNFQLP PGMVLVRSEN GQFLMIPQQA LAQMQAQAHA QSQSQNTMTP
RPATPTSAPP VQISAVQAPG APIIARQVTP TTIIKQVSQA QTTVQPTTTL QRPPVVQSQI
VLGGTAQTTT LGTATAVQTG TAQRTVQGAT AASTAATETM ENVKKCKNFL STLIKLASSG
KQSSETAANV KELVQNLLDG KIEAEDFTSR LYRELNSSPQ PYLVPFLKRS LPALRQLTPD
SAAFIQQSQQ QQPTTQATTA LTAVMLSGSV QRTAGKATAT VTSTLQQPVI SITQPTQVGV
SKQGQSTPLV IQQSQKAGTL IRPPQVTLTQ TPMVTLRQPH SRIMLTTPQQ IQLNQLQTVP
VVKPTVLPGS KAISTISMQA AAAQKNKLKE PGGGSFRDDD DINDVASMAG VNLSEESARI
LATNSELVGT LTRSCKDEAF LFSAPLQRRI LEIGKKHGIT DIHPDVVSYV SHAAQQRLQN
LVEKLSETAQ QKNISYKDDE RYEQASDVRA QLKFFEQLDQ IEKQRKDEQE REILMRAAKS
RSRQEDPEQL RLKQKAKEMQ QQELAQMRQR DANLTALAAI GPRKKRKVDS PGSGSGTEGS
EEEPRKVTPS QIAEYC
//
