ID A0A151NZX0_ALLMI Unreviewed; 617 AA.
AC A0A151NZX0;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=sphinganine-1-phosphate aldolase {ECO:0000256|ARBA:ARBA00038965};
DE EC=4.1.2.27 {ECO:0000256|ARBA:ARBA00038965};
DE AltName: Full=Sphingosine-1-phosphate aldolase {ECO:0000256|ARBA:ARBA00042568};
GN Name=SGPL1 {ECO:0000313|EMBL:KYO42432.1};
GN ORFNames=Y1Q_0022272 {ECO:0000313|EMBL:KYO42432.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO42432.1};
RN [1] {ECO:0000313|EMBL:KYO42432.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO42432.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|PIRSR:PIRSR602129-50};
CC -!- SIMILARITY: Belongs to the group II decarboxylase family. Sphingosine-
CC 1-phosphate lyase subfamily. {ECO:0000256|ARBA:ARBA00038302}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO42432.1}.
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DR EMBL; AKHW03001467; KYO42432.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A151NZX0; -.
DR STRING; 8496.A0A151NZX0; -.
DR eggNOG; KOG1383; Eukaryota.
DR PhylomeDB; A0A151NZX0; -.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR GO; GO:0016830; F:carbon-carbon lyase activity; IEA:InterPro.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0019752; P:carboxylic acid metabolic process; IEA:InterPro.
DR CDD; cd06450; DOPA_deC_like; 1.
DR Gene3D; 6.10.140.2150; -; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR002129; PyrdxlP-dep_de-COase.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR42735; -; 1.
DR PANTHER; PTHR42735:SF6; SPHINGOSINE-1-PHOSPHATE LYASE 1; 1.
DR Pfam; PF00282; Pyridoxal_deC; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000313|EMBL:KYO42432.1};
KW Pyridoxal phosphate {ECO:0000256|PIRSR:PIRSR602129-50};
KW Reference proteome {ECO:0000313|Proteomes:UP000050525}.
FT MOD_RES 402
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR602129-50"
SQ SEQUENCE 617 AA; 68983 MW; 273DE19CEA98C0FB CRC64;
MGRTSFPFQE QICHIPLIMR TPRLAALNAH LSRSKEKAFS LVAGEGWRGD GPAYRLSRDT
FPYKDIILMY LEKARSFVNG QCEGIEPWKL IGLTFASTLI LVWVHNFLFQ PESLTSRSKK
QFFKLIRKMP IVGGIIQKQI NKALDDVTSS LPFLKDEKGY IKALPAQGIS QDELLEKMKD
YSSMSEVHWE DGKVSGTVYS GEEKLTNLLV KVYEKFAWSN PLHPDIFPGL RKMEAEVVRM
ACTLFHGGPS SCGVMTSGGT ESILMACKAY RDLAYERGIK HPEMLVPKSV HAAFDKAAHY
FGLKIVHIPL TKTMQVDVQA MRRAISKNTA MLVCSAPQFP HGVMDPIEDV AKLALKYRIP
FHVDACLGGF LIVFMEKAGF PLQRPFDFRV EGVTSISADT HKYGYAPKGS SVLLYSDKKY
RHYQFFVAPD WQGGIYASPT MAGSRPGGII AACWATMMHM GEDGYVEATK KIINTARFIE
SELRKIDDIL IFGNPEVSVI SVGSDTFDIY RLSNLLATKG WNLNVLQFPR SIHLCITLLH
TKDGVAELFL EDVKECILEI MKDPGAKTTG MGAIYGMAQS IPDRSLVAEI SHAYLDSLYN
TDIPSSEKHM NGSPRHH
//
