ID A0A151P234_ALLMI Unreviewed; 422 AA.
AC A0A151P234;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Sulfotransferase {ECO:0000256|RuleBase:RU361155};
DE EC=2.8.2.- {ECO:0000256|RuleBase:RU361155};
GN Name=CHST4 {ECO:0000313|EMBL:KYO42980.1};
GN ORFNames=Y1Q_0012015 {ECO:0000313|EMBL:KYO42980.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO42980.1};
RN [1] {ECO:0000313|EMBL:KYO42980.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO42980.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-
CC pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
CC -!- SIMILARITY: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc
CC subfamily. {ECO:0000256|ARBA:ARBA00005530}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO42980.1}.
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DR EMBL; AKHW03001272; KYO42980.1; -; Genomic_DNA.
DR RefSeq; XP_019339268.1; XM_019483723.1.
DR AlphaFoldDB; A0A151P234; -.
DR STRING; 8496.A0A151P234; -.
DR GeneID; 102560896; -.
DR KEGG; amj:102560896; -.
DR CTD; 10164; -.
DR eggNOG; ENOG502RGC5; Eukaryota.
DR OrthoDB; 3031241at2759; -.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR GO; GO:0000139; C:Golgi membrane; IEA:InterPro.
DR GO; GO:0008146; F:sulfotransferase activity; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR016469; Carbohydrate_sulfotransferase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000863; Sulfotransferase_dom.
DR PANTHER; PTHR10704; CARBOHYDRATE SULFOTRANSFERASE; 1.
DR PANTHER; PTHR10704:SF71; SULFOTRANSFERASE; 1.
DR Pfam; PF00685; Sulfotransfer_1; 1.
DR PIRSF; PIRSF005883; Carbohydrate_sulfotransferase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000050525};
KW Signal-anchor {ECO:0000256|ARBA:ARBA00022968};
KW Transferase {ECO:0000256|RuleBase:RU361155, ECO:0000313|EMBL:KYO42980.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..50
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 68..379
FT /note="Sulfotransferase"
FT /evidence="ECO:0000259|Pfam:PF00685"
FT REGION 400..422
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 422 AA; 48315 MW; FD89F975876B1535 CRC64;
MPLQILREKL QFQERAGRRH RLPITMLTFS KVVVGVIVAV QAVALVHFFL LVPQRSSSLQ
QEKQSRVHIL ILSSWRSGSS FTGQLFSQHP DVFYLMEPAW HVWTTMHQNT AHSLHMAVRD
LVRSVFQCDM SVFDAYMPRG RKKSDLFQWE TSRALCSPPA CDVFQHSDII AKSHCRTVCS
KYPFSTVEQA CRLYSHVVLK EVRFFDLKVL YPLLSDPSLN IRIIHLVRDP RAVFLSREKV
APDLVRDSDI VVGPENNQGE MGPYNVMQEI CKSHIQIYTE GSQALPSSLQ GRYMLVRYED
IVKDPLEKAA ELYKFAELGF LPKLQRWVYN VTHGKGLGAG AFDVGSRNAV NVSQAWRKSL
PFHKIQKLQQ VCKDAMELLG YRLLASEEEQ KDMTLDLLLS QHPPTRQKQE LRTEKSPPAL
AS
//
