ID A0A151P4A5_ALLMI Unreviewed; 2343 AA.
AC A0A151P4A5;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=NAC-alpha domain-containing protein 1 {ECO:0000313|EMBL:KYO43759.1};
GN Name=NACAD {ECO:0000313|EMBL:KYO43759.1};
GN ORFNames=Y1Q_0020540 {ECO:0000313|EMBL:KYO43759.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO43759.1};
RN [1] {ECO:0000313|EMBL:KYO43759.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO43759.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- SIMILARITY: Belongs to the NAC-alpha family.
CC {ECO:0000256|ARBA:ARBA00009882}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO43759.1}.
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DR EMBL; AKHW03001125; KYO43759.1; -; Genomic_DNA.
DR STRING; 8496.A0A151P4A5; -.
DR eggNOG; KOG2239; Eukaryota.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR GO; GO:0005854; C:nascent polypeptide-associated complex; IEA:InterPro.
DR CDD; cd22054; NAC_NACA; 1.
DR CDD; cd14416; UBA_NACAD; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR Gene3D; 2.20.70.30; Nascent polypeptide-associated complex domain; 1.
DR InterPro; IPR016641; EGD2/NACA0like.
DR InterPro; IPR044034; NAC-like_UBA.
DR InterPro; IPR038187; NAC_A/B_dom_sf.
DR InterPro; IPR041907; NACAD_UBA.
DR InterPro; IPR002715; Nas_poly-pep-assoc_cplx_dom.
DR PANTHER; PTHR21713:SF4; GH09281P-RELATED; 1.
DR PANTHER; PTHR21713; NASCENT POLYPEPTIDE ASSOCIATED COMPLEX ALPHA SUBUNIT-RELATED; 1.
DR Pfam; PF19026; HYPK_UBA; 1.
DR Pfam; PF01849; NAC; 1.
DR SMART; SM01407; NAC; 1.
DR PROSITE; PS51151; NAC_AB; 1.
PE 3: Inferred from homology;
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000050525};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 2197..2262
FT /note="NAC-A/B"
FT /evidence="ECO:0000259|PROSITE:PS51151"
FT REGION 1..69
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 176..285
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 304..452
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 487..545
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 616..812
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 833..1001
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1068..1492
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1507..1541
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1653..1676
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1690..2115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2132..2172
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..25
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 313..356
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 419..434
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 508..544
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 712..730
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 780..808
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 938..964
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1193..1213
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1228..1242
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1277..1295
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1331..1346
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1405..1422
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1442..1476
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1690..1705
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1885..1899
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1923..1937
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1948..2008
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2063..2097
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2135..2153
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2343 AA; 244978 MW; 4B7849231C3C54EC CRC64;
MSSCPLTPCS DGHQETEQNA VNAADAQELQ VPPAPDGSGH ASCASTPSED TVPPKAMMPL
QASPTADSDC TPHGTMDPGV LAFLPAKKED RPQPEGASCD AAVGSSAAGL TALTECGQVL
LETDPKMCLA PKGLQEALAL DMPDTRIVMG EETRCSSEEE EAGAELQGLL MGAKAEEVAA
AGGESRDQED PGSEAAGKLP PQAMPADCPC PVPKASAHGP TCASRETGEL GEELADVPLS
QGETTADVPS PSPAPAKDPP DEVAGAELPQ AKPAGGLDPD LYFTAPSTPI KTVFSHLKHH
PYARDSLSEE QNDMENEGLC SPPTSPSGSY ITAEGGSWAS SGTSSTSPSC SPNLMAESEA
METPAVYGES LEEPARFPTS SCQSPEEEQE EEEEGDVTFD RLSSGNAAPL SLPAEEEEAD
GQTTPEEEDE WDSETATSVS QVPSKLQLEM SGERLVAEEK AFDLQGGEPG PEMLPVKVDI
LTLGQEDARP AAKEPAAGGC SPLAFPGLHS ESSCSSEAET PSSLQAETTA SSAELPSDFT
ESTDNDHMIP AVLLPFRGSL LFEAESMEIT LFPQGEVAEN DVVYGVEDDD STSASFLHSL
SETSINEGVD ESFAYQDDTS QSSDSASYNG EEDEKLYSAE QYAVVTDPTR EPGKPAAPED
SERGSSPSGS ESEMETSSDA SDTDEERVAF SALDLEPSGL HPAAIELQLE GDEVEGLAKG
EGEGERPPSV PSKDVPELIT VLAPVAEPKA AEEPLETVTP SPRPASAMGP EEPPPQTKSA
DGADDSQAEM GSSSESSLGQ QSSLSDMQEA LEKGLPSAGE CLIACFDTDE EAESFPGLES
AEPGVQLAPA EPWEEEESAP AAGQAGDAPT VDIGARLKES EARLLELLDQ DSTSPAGTRQ
SPEPGKDEGP LQALLGASEA AVLEQPEVSR ADHEPTGDSS AAFSSSEELE EASSLDQVNN
NEERGELFSP AELDSQPPLV PDATQPHMTP SSQGDPVAVL ESTFPPGELA ETPALDLHAM
QKGLQELQRQ LESGDAFLRP LGSGLPRLSS EQEIEKYVRS YFSTAQFSPA ASNGTEPAPS
QEAVDPEQDQ DAPTLLGLCS EAGETKDATS REPPLPALPG DQAPDANGSL DLGPSEEEEQ
TVGADEVSEP CVGPKRSASP APAVEELHPA EGESVDVTEL EVVDVGAGHD LAASSGSSAS
GSEESSQTDS VSAEVCPPAP GDPCPMDDSS TPATQGQALQ MPDTGSLEID IPDTRDGTMS
PPGALGEHEP STEDDLSLSD QDLSLSMSSN EALKGVPEQV ETPERGAVAG PGDLPDGERS
LPQELAEDSS QLPEPLEEEV APDTEPGQEE SESLSNAPED EELCSEAASE GVCLTDEERE
GKAVPPEMPW EALEGDAASE GGSSAFSDDL PSEDSLEGGQ SPSPTAPHIG AGEAPAPGSP
QEESDVTASS KESSPEPLDT SQSCAHTDSS FFTAPEESAG DSAGENTLLA HEAPALWHEE
TLLADASLPA VLEPEHAQGS TASPQRCRSP SEEPSPSPEP CLAVSLHYSS LPPAPHAAGM
EHVWLRASAP APGEPPLPLL FTASEREIYL GEQPLADTGA PSPEHPGMME VEEDVVEVEA
GPRPLSALLQ DPAVLAASRR LEEQEQISSM LQGSFGDLRA SPRRPGPPLA ESSPLVTEAQ
GVLASLKQEV FESSSGSSTP VSLEAAETQE EVLEATGPYH APESATMEDA AAAQVPEESI
PTHEELETVP EALPEPLESA EEAAGGEMVM ALEEQPVEED SSLPSEAPSE DEATQETSHE
AQEESAELEE EEMESRKGLE EAEGAQAPPE PAPAEQLLVE DQEAQQSQRP SDAVTHLGEE
EKPPSPDAPS PTPLDLSAEP AADSQPPRSP SPEPCPSPAA APGAEAEEAM EEAAAAESAP
EPCPSLAPAP LQPSRLEPAA PEPHAVEAQE PCSPPPAAPL LPAQLVSPEP EPCPGPARPA
SPGATGQEPP GPPCSQLIQV PPALPSSPPC SNERLQGPRD TSGLPMAKAG LAARDNQPAP
LDSRKRLEVL ENLVPPVPAK DKLPSSKDPR GRRPVPGSKE PRGKEVAPAE ERRAPRSAAP
SESSSSSEGE LPYRCPEIES LREAAGIAML EDKKPLAVPR GREANHKGSC NDSESNEESI
PELEEPDISE PRTVQTQAQL THSMGTGEET ISKAKQSRSE KKARKAMSKL GLRQIHGVTR
ITIRKSKNIL FVITKPDVFK SPASDIYIVF GEAKIEDLSQ QVHKAAAEKF KVPMEHSPLI
TETAPTLTIK EESEEEEEVD ETGLEVRDIE LVMAQANVSR PKAVRALRHN NNDIVNAIME
LTM
//
