ID A0A151P8F3_ALLMI Unreviewed; 880 AA.
AC A0A151P8F3;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Kinesin light chain 4 isoform D {ECO:0000313|EMBL:KYO45377.1};
GN Name=KLC4 {ECO:0000313|EMBL:KYO45377.1};
GN ORFNames=Y1Q_0015055 {ECO:0000313|EMBL:KYO45377.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO45377.1};
RN [1] {ECO:0000313|EMBL:KYO45377.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO45377.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC -!- SIMILARITY: Belongs to the kinesin light chain family.
CC {ECO:0000256|ARBA:ARBA00009622}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO45377.1}.
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DR EMBL; AKHW03000563; KYO45377.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A151P8F3; -.
DR STRING; 8496.A0A151P8F3; -.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005871; C:kinesin complex; IEA:InterPro.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0097193; P:intrinsic apoptotic signaling pathway; IEA:InterPro.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR018796; COA8.
DR InterPro; IPR002151; Kinesin_light.
DR InterPro; IPR015792; Kinesin_light_repeat.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR45783; KINESIN LIGHT CHAIN; 1.
DR PANTHER; PTHR45783:SF7; KINESIN LIGHT CHAIN 1; 1.
DR Pfam; PF10231; COA8; 1.
DR Pfam; PF13374; TPR_10; 2.
DR Pfam; PF13424; TPR_12; 2.
DR PRINTS; PR00381; KINESINLIGHT.
DR SMART; SM00028; TPR; 5.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS01160; KINESIN_LIGHT; 1.
DR PROSITE; PS50005; TPR; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00023212};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW Reference proteome {ECO:0000313|Proteomes:UP000050525};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}.
FT REPEAT 540..573
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 144..163
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 398..446
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 775..804
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 816..880
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 332..394
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 398..421
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 429..444
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 816..836
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 864..880
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 880 AA; 99880 MW; 23AF970A38BE5993 CRC64;
MWNQQFWANQ NVSFQQGKEE FIYSRLKAKG LQTRDETGHK ITLNAEEMAD FYKEFLSKNF
KKHMCYNRDW YKRAPKVTVI KSDSTDYGCF NQLEKNNSLK MIAVLHHATM THIQGELFGS
FWLETLVLRR FFSDDDGRKL CNASGLEERS EGPGCLPSTR ESGGSDLRCD FCMTQEFGCC
AMLPQVPVQI SYKLGCRVTT YYCFIYHASQ GQASPLSSQA INPLVISLVS VQSLILHDNL
TDQMYDNMST MVYLKEEKLE KLTQDEIIAK TKQVIQGLEA LKNEHNSILQ SLLETLKCLK
KDDETNLVEE KSNMIRKSLE MLELGLSEAQ VMMALSNHLN AVESEKQKLR AQVRRLCQEN
QWLRDELANT QQKLQKSEQS VAQLEEEKKH LEFMNQLKKY DDDISPSEDK DTDSTKEPLD
DLFPNDEDDQ GQGIQQQHSS AAAAAQQGGY EIPARLRTLH NLVIQYASQG RYEVAVPLCK
QALEDLEKTS GHDHPDVATM LNILALVYRD QNKYKDAANL LNDALAIREK TLGKDHPAVA
ATLNNLAVLY GKRGKYKEAE PLCKRALEIR EKVLGKDHPD VAKQLNNLAL LCQNQGKYEE
VEYYYQRALE IYQTKLGPDD PNVAKTKNNL ASCYLKQGKF KQAETLYKEI LTRAHEREFG
SVDDENKPIW MHAEEREECK GKQKDGTSFG EYGGWYKACK VDSPTVTTTL KNLGALYRRQ
GKFEAAETLE EAAMRSRKQG LDNVHKQRVA EVLNDPESIE KRRSRESLNV DVVKYESGPD
GGEEVSMSVE WNGDGTGSLK RSGSFSKLRA SIRRSSEKLV RKLKGGSSRD SEPKNPGMKR
ASSLNVLNMG GKATEDRFQE RNNCLTDSRA LSASHTDLAR
//
