ID A0A151P9G4_ALLMI Unreviewed; 658 AA.
AC A0A151P9G4;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 13-SEP-2023, entry version 17.
DE RecName: Full=Amidohydrolase-related domain-containing protein {ECO:0000259|Pfam:PF01979};
GN ORFNames=Y1Q_0021394 {ECO:0000313|EMBL:KYO45737.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO45737.1};
RN [1] {ECO:0000313|EMBL:KYO45737.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO45737.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- SIMILARITY: Belongs to the metallo-dependent hydrolases superfamily.
CC Hydantoinase/dihydropyrimidinase family.
CC {ECO:0000256|ARBA:ARBA00008829}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO45737.1}.
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DR EMBL; AKHW03000533; KYO45737.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A151P9G4; -.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0016810; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; IEA:InterPro.
DR CDD; cd01314; D-HYD; 1.
DR Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR Gene3D; 2.30.40.10; Urease, subunit C, domain 1; 1.
DR InterPro; IPR006680; Amidohydro-rel.
DR InterPro; IPR011778; Hydantoinase/dihydroPyrase.
DR InterPro; IPR011059; Metal-dep_hydrolase_composite.
DR InterPro; IPR032466; Metal_Hydrolase.
DR NCBIfam; TIGR02033; D-hydantoinase; 1.
DR PANTHER; PTHR11647:SF54; DIHYDROPYRIMIDINASE-RELATED PROTEIN 1; 1.
DR PANTHER; PTHR11647; HYDRANTOINASE/DIHYDROPYRIMIDINASE FAMILY MEMBER; 1.
DR Pfam; PF01979; Amidohydro_1; 1.
DR SUPFAM; SSF51338; Composite domain of metallo-dependent hydrolases; 2.
DR SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000050525}.
FT DOMAIN 150..539
FT /note="Amidohydrolase-related"
FT /evidence="ECO:0000259|Pfam:PF01979"
FT REGION 21..71
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 599..658
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 45..59
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 601..635
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 658 AA; 71457 MW; 1D042CB0DEBB01D9 CRC64;
MFAAVEGAYE NKTIDFDAYS VGKKGSRTPR SGSRHDMLDG GDNYSETASD VSEVSGSVIS
SPGDRDDKTP GVEIRFPLGK ELLQGQDNGK GKKSIPHITS DRLLIKGGRI INDDHSFYAD
IYLEDGLIKQ IGENLIVPGG VKTIEANGRM VIPGGIDVNT YLQKPYQGMT AVDDFYQGTK
AALAGGTTMI IDHVLPGLGS SLLTSFEKWH EAADTKSCCD YSLHVDITSW YDGIREELEI
LVQDKGVNSF QVYMAYKDLY QMSDSQLYEA FTFLKSLGAV MMVHAENGDL IAQEQKRILE
MGITGPEGHA LSRPEELEAE AVFRAITIAS RINCPVYITK VMSKSAADII ALARKKGPLV
FGEPITASLG TDGTHYWSKN WAKAAAFVTS PPLSPDPTTP DHLNSLLACG DLQVTGSGHC
PYSTAQKAIG KENFTMIPEG VNGIEERMTV VWDKAVATGK MDENQFVAVT STNAAKIFNL
YPRKGRIAVG SDADVVIWDP DKVKTITAKS HKSAVEYNIF EGMECHGAPL VVISQGKIVF
EDGNLHVNKG MGRFIPRKSF PEYLYQRVKI RNKVGGLQGV SRGMYDGPVY EIPATPKYAT
PAPSAKSSPA KNQPPPIRNL HQSNFSLSGA QIDDNNPRRT GHRIVAPPGG RSNITSLG
//
