ID A0A151PC69_ALLMI Unreviewed; 1773 AA.
AC A0A151PC69;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=EF-hand calcium-binding domain-containing protein 3 isoform F {ECO:0000313|EMBL:KYO46524.1};
GN Name=EFCAB3-1 {ECO:0000313|EMBL:KYO46524.1};
GN ORFNames=Y1Q_0018319 {ECO:0000313|EMBL:KYO46524.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO46524.1};
RN [1] {ECO:0000313|EMBL:KYO46524.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO46524.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO46524.1}.
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DR EMBL; AKHW03000499; KYO46524.1; -; Genomic_DNA.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00051; EFh; 3.
DR Gene3D; 1.10.238.10; EF-hand; 8.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR PANTHER; PTHR22656:SF1; EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 13; 1.
DR PANTHER; PTHR22656; UNCHARACTERIZED; 1.
DR Pfam; PF13499; EF-hand_7; 1.
DR Pfam; PF13833; EF-hand_8; 1.
DR SMART; SM00054; EFh; 14.
DR SUPFAM; SSF47473; EF-hand; 8.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 5.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000050525};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 622..657
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 989..1024
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 1138..1173
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 1387..1422
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 1423..1458
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 74..110
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 153..187
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 374..416
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 438..482
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 77..92
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 154..176
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 374..396
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1773 AA; 201571 MW; EC2DD914549F1E0A CRC64;
MEMDKMELWV MDRPPWECVL RIRSLLQENP SSTSLQSIWS EFQTGIEENM ESWELPDQKT
PQKPRFSSVI EAWKQPSNHR STERKKHPPA FPAAKAHEQL RASSTTPEHD ATRSFLLMEQ
ASPVSCIKRR QVPKTDKATE ITPSFEMMLK RAALSKKKKS MSKGFSRTRQ KKRKAASTSP
RQSFPKAHRK SKVLYNLYMN LYDEVGEMEA WTMQKAEGLP KACFIFSAIR NGEINVNDLL
LTLHTLGILV TSEEMREALK DVDIDINGNL NFSNFLDVLN ETSSFTLTET FQVIHRAFSK
MRNGMIAVAD LHPTLISLVV DLTFEKLQEA MAQVYVNKEG RVNISDFVMA LSDLEHHYED
VDFMNAYDTL KPRKHQDEFD TDNRKEKSRR RTRFSQDIYS LPKANGRESV KSSDQKSSVQ
FFQEKRLSRF DFEGSQEKSW EASKRHSTHK NSLVRTTTTE ELEDMEPPSA YEGDRVPQQS
TTAKEVVSLA LGAGEERAPD LEVAEESLAN SRAAWEMVAL QNTFKVVNKI KGDTTEDAEL
HSTLQAMGVH LTDEEFHKAL KKVTLERGIV NVNDFMIALS NTQHFSDFSE LKDATEATSK
TESDKVAVGD LLTCMNNMGI QLSDEEFQEA LKIVFVDGDG KVDFKEFLKG LTGTQQSSEN
IEMEEAMKAI CSIKEDRVDI QQLDSIMSSR GIHLSPEEIQ NALELITCKE DGKVNLEDFM
MALTKCQQCS RTEKDKVNIR SLDCILDNMG IFLTHREIQE ALKNITTDDS GKVNLTKFMT
SVRALRKFSH GEGKEAYVGA LDSILTEMGV HLTNKELQEA LKYVTVDENG KVKVSDFLES
MISTRRASLA DRDKVHVSHL ESILGRMEVF LSEQEFQEAL KHTNVGVNRR VNLIEFMKAA
RTAQRKSRLE GEKVDVNSLD STLANMGICL TAEELQKVLG QVTISSDGKV DLKDVMERVM
STQWPSQYDR DKVDIQHLDS ILINMGVHLT NEELQEALNH MTVDADGNMN LREFMEVVET
VQKLPSAEED RTDVSNLDNI GIHLTSEEMQ EALKHITDRT DGKGNLSEFT KGVRTIQKLP
LSEGDRVDVS NLDSILSSLG IHLTSEEMQE ALKHIAVDGD KVDIQHLDSI LSSMRVYLIN
EELQEALKHM TVDEDGKVNL GEFMEGLRAL QKSPTSKEDR DDVSNLDSVL TSMGVHLTKE
EMQEALMPIA VDGDKVGIQH LDSILSSMGI YVTNEELQEA LKHTPVDDGK VNLSELMKGL
RDVQKLPPVE GEKDRVDVSN LDTILASMGI HLTSEEIQKE LKHITVDGDD KISLSTFMNS
MMSTQRPSQI KKKPGPNFDQ TPKTDMTLKS MPKKMMLKPL PKKIRGELSA ILLDRSKCKA
AKNMTRNQLE AFYDAYNFFT KDSDGTIDLH ELEMTTKKLG LNLTEQEAYD ELAYADVDRD
GKVNFLDFLT IISDTKRFIQ AVAPEKGSLD SFNLVDATGI LMFEVLSKLM EKSALSRRTM
LEIVSYYRNK FLDCTSKKAW MVMDSFICHD KRLHKLKKHQ GHQKGAASPT CAFTKVAHIP
VMNNKQLESC VETLRACTST SNSPYAQVPI FPLLPNRDGV TKTRPKKDLQ KLEMQRRKKR
IPSFENHFFH KRNWVHEATA FKPPDDFQER RTSLSLSPQL LDKERWLTME NLNEIRTNVK
QVTDTYRQGI ALQERNRILK LWQKVHGRET GLEAGNDSFY HTFSTYSWSW NICQELVTPN
DLRKYDNKLY HRQHSSAFST EAGIKDGKGR EKQ
//
