ID A0A151PIZ6_ALLMI Unreviewed; 238 AA.
AC A0A151PIZ6;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Protein S100-A4 {ECO:0000256|ARBA:ARBA00023809};
DE AltName: Full=Metastasin {ECO:0000256|ARBA:ARBA00031687};
DE AltName: Full=S100 calcium-binding protein A4 {ECO:0000256|ARBA:ARBA00032790};
GN Name=S100A16 {ECO:0000313|EMBL:KYO48989.1};
GN ORFNames=Y1Q_0000795 {ECO:0000313|EMBL:KYO48989.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO48989.1};
RN [1] {ECO:0000313|EMBL:KYO48989.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO48989.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}. Secreted
CC {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the S-100 family.
CC {ECO:0000256|ARBA:ARBA00007323}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO48989.1}.
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DR EMBL; AKHW03000146; KYO48989.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A151PIZ6; -.
DR STRING; 8496.A0A151PIZ6; -.
DR eggNOG; ENOG502S6F9; Eukaryota.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0046914; F:transition metal ion binding; IEA:InterPro.
DR CDD; cd00213; S-100; 1.
DR Gene3D; 1.10.238.10; EF-hand; 2.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR034325; S-100_dom.
DR InterPro; IPR001751; S100/CaBP7/8-like_CS.
DR InterPro; IPR013787; S100_Ca-bd_sub.
DR PANTHER; PTHR11639:SF51; PROTEIN S100-A4; 1.
DR PANTHER; PTHR11639; S100 CALCIUM-BINDING PROTEIN; 1.
DR Pfam; PF13202; EF-hand_5; 1.
DR Pfam; PF01023; S_100; 2.
DR SMART; SM00054; EFh; 2.
DR SMART; SM01394; S_100; 2.
DR SUPFAM; SSF47473; EF-hand; 2.
DR PROSITE; PS00018; EF_HAND_1; 2.
DR PROSITE; PS50222; EF_HAND_2; 2.
DR PROSITE; PS00303; S100_CABP; 2.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000050525}.
FT DOMAIN 65..100
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 187..222
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
SQ SEQUENCE 238 AA; 26987 MW; 14D98B80270C4BB6 CRC64;
MSAGMTNVQQ QHTDLECAVE MLVKNFEKYA GGGGCCCRKQ PRRISKKDFR KMLTRELNHM
LTDTGNKRAA DKLICDLDEN KDGRISFEEY WTLIGGIASP IAGLIRQQEQ SIKFSNRLSG
QHLSAYFLPR CLAPRSAMAH PLEQALQVIV STFHKYSGKE GDKLKLNKAE LKDLMLKELP
SFISKKTDDA SFQKMLSNLD SNRDNEVDFQ EYATFLACAA MMCNDIFEGC PDKMPRRK
//
