ID A0A151RM89_CAJCA Unreviewed; 1726 AA.
AC A0A151RM89;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=1-phosphatidylinositol-3-phosphate 5-kinase {ECO:0000256|ARBA:ARBA00012009};
DE EC=2.7.1.150 {ECO:0000256|ARBA:ARBA00012009};
GN ORFNames=KK1_034900 {ECO:0000313|EMBL:KYP43622.1};
OS Cajanus cajan (Pigeon pea) (Cajanus indicus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Cajanus.
OX NCBI_TaxID=3821 {ECO:0000313|EMBL:KYP43622.1, ECO:0000313|Proteomes:UP000075243};
RN [1] {ECO:0000313|EMBL:KYP43622.1, ECO:0000313|Proteomes:UP000075243}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Asha {ECO:0000313|Proteomes:UP000075243};
RX PubMed=22057054; DOI=10.1038/nbt.2022;
RA Varshney R.K., Chen W., Li Y., Bharti A.K., Saxena R.K., Schlueter J.A.,
RA Donoghue M.T., Azam S., Fan G., Whaley A.M., Farmer A.D., Sheridan J.,
RA Iwata A., Tuteja R., Penmetsa R.V., Wu W., Upadhyaya H.D., Yang S.P.,
RA Shah T., Saxena K.B., Michael T., McCombie W.R., Yang B., Zhang G.,
RA Yang H., Wang J., Spillane C., Cook D.R., May G.D., Xu X., Jackson S.A.;
RT "Draft genome sequence of pigeonpea (Cajanus cajan), an orphan legume crop
RT of resource-poor farmers.";
RL Nat. Biotechnol. 30:83-89(2012).
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DR EMBL; KQ483659; KYP43622.1; -; Genomic_DNA.
DR STRING; 3821.A0A151RM89; -.
DR OMA; RCESMIV; -.
DR Proteomes; UP000075243; Unassembled WGS sequence.
DR GO; GO:0000285; F:1-phosphatidylinositol-3-phosphate 5-kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0046488; P:phosphatidylinositol metabolic process; IEA:UniProtKB-UniRule.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd03334; Fab1_TCP; 1.
DR CDD; cd15725; FYVE_PIKfyve_Fab1; 1.
DR CDD; cd17300; PIPKc_PIKfyve; 1.
DR Gene3D; 3.30.810.10; 2-Layer Sandwich; 1.
DR Gene3D; 3.50.7.10; GroEL; 1.
DR Gene3D; 3.30.800.10; Phosphatidylinositol Phosphate Kinase II Beta; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR002423; Cpn60/GroEL/TCP-1.
DR InterPro; IPR027409; GroEL-like_apical_dom_sf.
DR InterPro; IPR044769; PIKfyve_PIPKc.
DR InterPro; IPR027483; PInositol-4-P-4/5-kinase_C_sf.
DR InterPro; IPR002498; PInositol-4-P-4/5-kinase_core.
DR InterPro; IPR027484; PInositol-4-P-5-kinase_N.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR45748; 1-PHOSPHATIDYLINOSITOL 3-PHOSPHATE 5-KINASE-RELATED; 1.
DR PANTHER; PTHR45748:SF7; 1-PHOSPHATIDYLINOSITOL 3-PHOSPHATE 5-KINASE-RELATED; 1.
DR Pfam; PF00118; Cpn60_TCP1; 1.
DR Pfam; PF01363; FYVE; 1.
DR Pfam; PF01504; PIP5K; 1.
DR SMART; SM00064; FYVE; 1.
DR SMART; SM00330; PIPKc; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF52029; GroEL apical domain-like; 1.
DR SUPFAM; SSF56104; SAICAR synthase-like; 1.
DR PROSITE; PS51455; PIPK; 1.
DR PROSITE; PS50178; ZF_FYVE; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00781};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000256|PROSITE-
KW ProRule:PRU00781}; Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00781};
KW Reference proteome {ECO:0000313|Proteomes:UP000075243};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW ProRule:PRU00781}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT DOMAIN 36..102
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT DOMAIN 1366..1690
FT /note="PIPK"
FT /evidence="ECO:0000259|PROSITE:PS51455"
FT REGION 1112..1147
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1177..1199
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1703..1726
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1726 AA; 193920 MW; 97A305733B6E4ECF CRC64;
MDAVDKTFSD LVSIVKSWIP WRSEPGNVSR DFWMPDQSCR VCYECDSQFT LFHRKHHCRL
CGRIFCNKCT TNSIPASFSN QRNSRDELEK IRVCNYCYKQ WEQGVVAFDK SIPVSNLDHS
ASASTSSSVS SKTSATANSS NITLCSMPYS VGSYQPMQQG SVLNLHQSPV RAKDADADRE
GFSALGGRSD LVADLGDPLP NKYAFSINRS DDDEDEYGVY RSDMRHYPQV NSYYGQSELN
GIDNIDGLQK VDLDGENINA KLPSNYSFDT QGLEGAPVIS KNEDEPDICD ENEAPSSLYV
SEDVNAEPVD FENNGLLWLP PEPEDEEDEQ EAILYDDDDD NDGNAIGEWG YLRTSSSFGS
GENRHRERSG EEHKKVMKNV VDGHFRALVS QLLQVENLPV EEEDENSWLE IVTSLSWEAA
TLLKPDMSKS GGMDPAGYVK VKCIACGSRI ESVVVKGVVC KKNVAHRRMT SKVDKPRLLI
LGGALEYQRV TNLLSSVDTL LQQEMDHLKM AVAKIASHQP NILLVEKSVS RYAQEYLLAK
DISLVLNVKR PLLERVARCT GTQIVPSIDH LSSQKLGYCE TFRVEKFVED LNSAGQGGKK
TMKTLMFFEG CPKPLGFTIL LRGADKDELK KVKHVVQYGV FAAYHLALET SFLADEGVSM
PEIPLNSLAL PDDKASSIQR SISTVPGFRN SISESHHNML LSCTSRDRNE MDSKQPLVEE
NSVVDNTMVV MDDPTVDDPG TSEKLYQGIS VDTPQNGDLK ISAIQLSGSG SLSPIDVQNH
PESLGITNEE PILEKEEFPP SPSDHQSILV SLSSRCVWKG TVCERSHLFR IKYYGNFDKP
LGRFLRDHLF DQGYRCHSCE MPTEAHVHCY THRQGTLTIS VKKLPEIILP GERDGKIWMW
HRCLRCPRIN GFPPATQRIV MSDAAWGLSF GKFLELSFSN HAAASRVASC GHSLHRDCLR
FYGFGRMVAC FRYASIDVHS VYLPPHELIF DYRNQDWIQQ ESDEVVNRAE LLFSDVLNGL
SQIGEKKSSA VQINNGLKTP ELRRQVVELE GMLQKEKLEF EETLQKILNQ EKRNGQPEID
VLEINRLWRQ LLFQSYMWDH RLVYAANLVN SNNESGSSSP ISEDKENPTD ENQMSIKSID
GDPKLNESPC LGGGSVVIDG KISQDDALHQ EIDMAKNKNH EKDEEPSLSN CKSISDQSDL
EPEFGVRRTL SDGPFPVIPS LSETLDAKWT GEDHSGFGIQ KDNTSVNPDN MTDALTISVQ
KETHNLLDRT EDQNGSKSFF SSFKGHDNVE DSSSWLGMPF LNFYRQFNKN LFASTQKFDT
LVDYNPVYVS SFRKQELQGG ARLLLPIGVN DTVIPVYDDE PSSIIAYALM SPDYHFQLGD
EGERPKEEEM IFSMSGSRNP SILDPMSYTK AMHAKVSFGE DGPLGKVKYS VTCYYAKRFE
ALRRVCCPSE LDYIRSLSRC KKWGAQGGKS NVFFAKTLDD RFIIKQVTKT ELESFFKFGP
EYFKYLSESI ATGSPTCLAK ILGIYQVTSK HLKGGKESRM DVLVMENLLF RRTVTRLYDL
KGSSRSRYNA DSSGKNKVLL DQNLIEAMPT SPIFVGNKAK RLLERAVWND SGFLASVDVM
DYSLLVGMDE EKHELVIGII DFMRQYTWDK HLETWVKASG ILGGPKNTPP TVISPKQYKK
RFRKAMTTYF LMLPDQWSPN APSILTSNSQ SDLGEDNNTQ SRTPAE
//
