ID A0A151SXQ2_CAJCA Unreviewed; 1431 AA.
AC A0A151SXQ2;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Pleiotropic drug resistance protein 1 {ECO:0000313|EMBL:KYP59578.1};
GN ORFNames=KK1_015014 {ECO:0000313|EMBL:KYP59578.1};
OS Cajanus cajan (Pigeon pea) (Cajanus indicus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Cajanus.
OX NCBI_TaxID=3821 {ECO:0000313|EMBL:KYP59578.1, ECO:0000313|Proteomes:UP000075243};
RN [1] {ECO:0000313|EMBL:KYP59578.1, ECO:0000313|Proteomes:UP000075243}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Asha {ECO:0000313|Proteomes:UP000075243};
RX PubMed=22057054; DOI=10.1038/nbt.2022;
RA Varshney R.K., Chen W., Li Y., Bharti A.K., Saxena R.K., Schlueter J.A.,
RA Donoghue M.T., Azam S., Fan G., Whaley A.M., Farmer A.D., Sheridan J.,
RA Iwata A., Tuteja R., Penmetsa R.V., Wu W., Upadhyaya H.D., Yang S.P.,
RA Shah T., Saxena K.B., Michael T., McCombie W.R., Yang B., Zhang G.,
RA Yang H., Wang J., Spillane C., Cook D.R., May G.D., Xu X., Jackson S.A.;
RT "Draft genome sequence of pigeonpea (Cajanus cajan), an orphan legume crop
RT of resource-poor farmers.";
RL Nat. Biotechnol. 30:83-89(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCG family.
CC PDR (TC 3.A.1.205) subfamily. {ECO:0000256|ARBA:ARBA00006012}.
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DR EMBL; CM003612; KYP59578.1; -; Genomic_DNA.
DR SMR; A0A151SXQ2; -.
DR STRING; 3821.A0A151SXQ2; -.
DR OMA; QYQIMWG; -.
DR OrthoDB; 1384804at2759; -.
DR Proteomes; UP000075243; Chromosome 10.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03233; ABCG_PDR_domain1; 1.
DR CDD; cd03232; ABCG_PDR_domain2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR034001; ABCG_PDR_1.
DR InterPro; IPR034003; ABCG_PDR_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR013581; PDR_assoc.
DR PANTHER; PTHR48040:SF40; ABC TRANSPORTER DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR48040; PLEIOTROPIC DRUG RESISTANCE PROTEIN 1-LIKE ISOFORM X1; 1.
DR Pfam; PF01061; ABC2_membrane; 2.
DR Pfam; PF00005; ABC_tran; 2.
DR Pfam; PF08370; PDR_assoc; 1.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000075243};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 521..542
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 554..574
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 605..628
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 640..658
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 664..687
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 743..766
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1178..1196
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1208..1234
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1291..1315
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1321..1340
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1352..1371
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1400..1423
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 152..425
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 832..1084
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 1431 AA; 161969 MW; BBCE7B14570FF9BD CRC64;
MEGGDVYKAI NSLRSRSSKV WRNSGEDVFS RSSRGEDDEE ALKWAALERL PTYNRLKKGL
LTASHGAVNE IDVTDLGFQE RQKLLDKLVK VAEEDNEKFL LKLKERIERV GLDIPTIEVR
YEHLNIEAEA IVGSRALPSF INAVTNVIEG FLNILHIIPS KKKHVTILKD VSGIIKPRRM
TLLLGPPSSG KTTLLLALSG KLDKSLKVSG RVTYNGHEMN EFVPQRTAAY ISQHDVHMGE
MTVRETLAFS ARCQGVGSRY DMLSELSRRE KATNIKPDPD LDFYMKATAT AGQESSIVTD
YIMKILGLDI CADTMVGNEM WRGISGGQRK RLTTGEMLVG PANALFMDEI STGLDSSTTF
QIVSSLRQYV HILNGTVVIS LLQPAPETYD LFDDIILISD GQVVYHGPRE YVLDFLESMG
FRCPERKGVA DFLQEVTSKK DQAQYWVRSD QPYRFVTVTQ FAEAFQSFHI GRKLAEELIV
PFDKTKNHPA ALTTKKYGIN KKELLKANFS REYLLMKRNS FVYIFKLCQI FVIALIAMTV
FFRTEMHHEN LKDAGVYGGA IFFTLSIIMF NGMVELSLTI VRLPVFYKQR DSLFYPSWAF
SIPSWILKIP ITIVEVAVWV CLTYYVIGFD PNVGRFFKEF LVLLFVSQMA AGLFRAIAGL
CRNMIVTNTL GSFSLLVLYT LGGFVLSKKH IKSWWIWGFW ISPIMYGQNA LMVNEFLGNS
WHNATHNLGV QYLESRAFFT HSYWYWLGIG ALVGYTLLFN MIYGFALEFL DSFDKQQAIK
TEEEPETNTP NERTVTEVEL PCIEGSGKSD SVVESSHGKK KGMILPFEPH SIIFDEIVYS
VVMPQEMKQQ GAQEDKLMLL KGVSGAFRPG VLTALMGVSG AGKTTLMDVL AGRKTGGYIE
GSIKISGYPK KQETFARISG YCEQNDIHSP HVTVYESLLY SAWLRLPSSV DSNTRQMFIE
EVMELVELNP LRKSLVGLPG VSGLSTEQRK RLTIAVELVA NPSIIFMDEP TSGLDARAAA
IVMRTVRNTV DTGRTVVCTI HQPSIDIFEA FDELLLLKRG GQEIYVGPLG RHSRHLIKDF
ESIEGVSKIK AGYNPATWML EVTTTTQELS LGVDFAELYK NSDLYRRNKQ LIQELGQPSP
GSKDLHFQTQ YSQSFWVQCQ ACLWKQHLSY WRNPPYTVVR FFFVILISLF FGSSFWDLGG
KHSDRQDLLN ALGSMFIAVL FIGVQHCNSV LPVVSVERSV FYREKAAGMY SALPYAFAQI
LVELPYIFSQ AMIYGVIVYA MIGFEWTAKK FFWYLFFMYF TLLYYIFYGM MAVALTPNQH
TASIVASAFF AIWILFSGFV ITRPNIPKWW RWYYWACPVS WSLYGLVASQ FGDIMTPMTS
EGNKPVKYFV EDYFGIKHDF LGACAVAVPG FGILFAFIFG IAIKNLNFQN R
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