ID A0A151T850_CAJCA Unreviewed; 1097 AA.
AC A0A151T850;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=KK1_017751 {ECO:0000313|EMBL:KYP63184.1};
OS Cajanus cajan (Pigeon pea) (Cajanus indicus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Cajanus.
OX NCBI_TaxID=3821 {ECO:0000313|EMBL:KYP63184.1, ECO:0000313|Proteomes:UP000075243};
RN [1] {ECO:0000313|EMBL:KYP63184.1, ECO:0000313|Proteomes:UP000075243}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Asha {ECO:0000313|Proteomes:UP000075243};
RX PubMed=22057054; DOI=10.1038/nbt.2022;
RA Varshney R.K., Chen W., Li Y., Bharti A.K., Saxena R.K., Schlueter J.A.,
RA Donoghue M.T., Azam S., Fan G., Whaley A.M., Farmer A.D., Sheridan J.,
RA Iwata A., Tuteja R., Penmetsa R.V., Wu W., Upadhyaya H.D., Yang S.P.,
RA Shah T., Saxena K.B., Michael T., McCombie W.R., Yang B., Zhang G.,
RA Yang H., Wang J., Spillane C., Cook D.R., May G.D., Xu X., Jackson S.A.;
RT "Draft genome sequence of pigeonpea (Cajanus cajan), an orphan legume crop
RT of resource-poor farmers.";
RL Nat. Biotechnol. 30:83-89(2012).
CC -!- SIMILARITY: Belongs to the helicase family. RecQ subfamily.
CC {ECO:0000256|ARBA:ARBA00005446}.
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DR EMBL; CM003610; KYP63184.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A151T850; -.
DR STRING; 3821.A0A151T850; -.
DR OMA; VNWSDHA; -.
DR Proteomes; UP000075243; Chromosome 8.
DR GO; GO:0043138; F:3'-5' DNA helicase activity; IEA:EnsemblPlants.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0071215; P:cellular response to abscisic acid stimulus; IEA:EnsemblPlants.
DR GO; GO:0070417; P:cellular response to cold; IEA:EnsemblPlants.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR GO; GO:0000724; P:double-strand break repair via homologous recombination; IEA:EnsemblPlants.
DR CDD; cd17920; DEXHc_RecQ; 1.
DR CDD; cd18794; SF2_C_RecQ; 1.
DR Gene3D; 1.10.150.80; HRDC domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR010997; HRDC-like_sf.
DR InterPro; IPR002121; HRDC_dom.
DR InterPro; IPR044876; HRDC_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032284; RecQ_Zn-bd.
DR InterPro; IPR018982; RQC_domain.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR NCBIfam; TIGR00614; recQ_fam; 1.
DR PANTHER; PTHR13710:SF153; ATP-DEPENDENT DNA HELICASE Q-LIKE 4A; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00570; HRDC; 1.
DR Pfam; PF16124; RecQ_Zn_bind; 1.
DR Pfam; PF09382; RQC; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00341; HRDC; 1.
DR SMART; SM00956; RQC; 1.
DR SUPFAM; SSF47819; HRDC-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50967; HRDC; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:KYP63184.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000075243}.
FT DOMAIN 373..530
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 555..716
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 914..996
FT /note="HRDC"
FT /evidence="ECO:0000259|PROSITE:PS50967"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 67..87
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1001..1048
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 200..246
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1097 AA; 122977 MW; 9EDFCA9C32DEA9BD CRC64;
MFSVPPKKPC HEEPLPGNAT FGVQQSENIQ GSRRVQVEKA WIALSSLQNF SRNYVQPGKS
VEVTPQLRED RRTTSFPGGY ENDKNRCPDV STTPIVINHI SQGLVGSVTS VNNHTKYTGQ
INESSKCMIA DIGDDDLLGN IDVDQIVEKY QSTCTPKPSI SKLPPTTPTA YNDNVLPPEL
CLDCIHGYKL GLCPEAASHL QELKDNLIAI SNELLDNSEN LNSTQIAKLR NDRSQLNKQI
QQLEQYINCG NLNEERQKSH QFASTAPPTS FMYETPQQTV LCNGPKRDAY MGNGTYGSSF
QCLPSFSVDN YSMSSAPVER EAFVPKIIEV NYIEGSGDKR WSSRDFPWTK ELEVNNKRVF
GNHSFRPNQR EVINATMSGC DVFVLMPTGG GKSLTYQLPA LICPGITLAN IPAAYLSANM
EWAEQQEILR ELNSDCCKYK LLYVTPEKVA KSDVLLRQLD NLHVRELLAR IVIDEAHCVS
QWGHDFRPDY QGLGILKQKF PNTPVLALTA TATASVKEDV VQALGLVNCI IFRQSFNRPN
LWYSVIPKTK KCLEDIDKFI RENHFDECGI IYCLSRMDCE KVAEKLRECG HKCAFYHGTM
DPAQRASVQK QWSKDEINII CATVAFGMGI NKPDVRFVIH HSLPKSIEGY HQECGRAGRD
GQRSSCVLYY NYSDYIRVKH MLSQGAIEQS PMTSGYNRSN MTNSGRVLET NTENLMRMVS
YCENDVDCRR LLQLVHFGEK FNSSTCQKTC DNCLKITSFI EKDVTEIAKQ LVELVKLMGQ
RFSSSHILEV YRGSLSQLVK KHRHETVSLH GAGKRLGKGE ASRVLHHLVV EDFLVEEVKK
SDYYGSVSSI LKVNEPKVRN LYAGQRIILR FPSSVKASKP GKSDITPAKG SLTSGKPNVT
LIDTPPEPQT EVDLNLSAKL YTALRMLRTS LVREAGEGVM AYHIFGNATL QQISKRVPRT
KEELLDINGI SKTKVSKYGD RLLEIIENTI NEYYKLEKVS SGSKGSADSC KRRRGTNGGL
NANDEDDDAL TNSTGRSKRR TVKKQTRKDV VYDSPEEDYF HGCSDEDLDF DVIEIDALDQ
VTCKNAAGRV LPQWTAS
//
