ID A0A151TQ93_CAJCA Unreviewed; 407 AA.
AC A0A151TQ93;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=Glycerate dehydrogenase {ECO:0000313|EMBL:KYP69180.1};
DE EC=1.1.1.26 {ECO:0000313|EMBL:KYP69180.1};
DE EC=1.1.1.79 {ECO:0000313|EMBL:KYP69180.1};
GN ORFNames=KK1_008367 {ECO:0000313|EMBL:KYP69180.1};
OS Cajanus cajan (Pigeon pea) (Cajanus indicus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Cajanus.
OX NCBI_TaxID=3821 {ECO:0000313|EMBL:KYP69180.1, ECO:0000313|Proteomes:UP000075243};
RN [1] {ECO:0000313|EMBL:KYP69180.1, ECO:0000313|Proteomes:UP000075243}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Asha {ECO:0000313|Proteomes:UP000075243};
RX PubMed=22057054; DOI=10.1038/nbt.2022;
RA Varshney R.K., Chen W., Li Y., Bharti A.K., Saxena R.K., Schlueter J.A.,
RA Donoghue M.T., Azam S., Fan G., Whaley A.M., Farmer A.D., Sheridan J.,
RA Iwata A., Tuteja R., Penmetsa R.V., Wu W., Upadhyaya H.D., Yang S.P.,
RA Shah T., Saxena K.B., Michael T., McCombie W.R., Yang B., Zhang G.,
RA Yang H., Wang J., Spillane C., Cook D.R., May G.D., Xu X., Jackson S.A.;
RT "Draft genome sequence of pigeonpea (Cajanus cajan), an orphan legume crop
RT of resource-poor farmers.";
RL Nat. Biotechnol. 30:83-89(2012).
CC -!- SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid
CC dehydrogenase family. {ECO:0000256|RuleBase:RU003719}.
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DR EMBL; CM003605; KYP69180.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A151TQ93; -.
DR STRING; 3821.A0A151TQ93; -.
DR OMA; RMMVEGH; -.
DR Proteomes; UP000075243; Chromosome 3.
DR GO; GO:0047964; F:glyoxylate reductase (NAD+) activity; IEA:UniProtKB-EC.
DR GO; GO:0030267; F:glyoxylate reductase (NADP+) activity; IEA:UniProtKB-EC.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR CDD; cd05301; GDH; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR InterPro; IPR029752; D-isomer_DH_CS1.
DR InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR10996; 2-HYDROXYACID DEHYDROGENASE-RELATED; 1.
DR PANTHER; PTHR10996:SF257; GLYCERATE DEHYDROGENASE HPR, PEROXISOMAL; 1.
DR Pfam; PF00389; 2-Hacid_dh; 1.
DR Pfam; PF02826; 2-Hacid_dh_C; 2.
DR SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00065; D_2_HYDROXYACID_DH_1; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|RuleBase:RU003719,
KW ECO:0000313|EMBL:KYP69180.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000075243}.
FT DOMAIN 34..354
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase
FT catalytic"
FT /evidence="ECO:0000259|Pfam:PF00389"
FT DOMAIN 130..202
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02826"
FT DOMAIN 231..329
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02826"
SQ SEQUENCE 407 AA; 44929 MW; 434AAF70C4A2F52C CRC64;
MAKPVSIEVW NPNGKYRVVS TKSMPGTRWI NLLIQNDCRL EICTEKKTIL SIEDIIALIG
DKCDGVIGQL TEEWGEELFS ALSRAGGKAF SNMAVGYNNV DVDAANKYGV AVGNTPGVLT
ETTAELAASL SLAAARRIVE ADEFMRAGLY DGWLPHLFVG NLLKGQTVGV IGAGRIGSAY
ARMMVEGFKM NLIYFDLYQA TRLEKFVTGM FLPTYGAFLK ASGETPVTWK RASSMDEVLQ
EADIISLHPV LDKTTYHLVN KERLAKMKKA REAILINCSR GPVIDEAALV EHLKHNPMFR
VGLDVFEDEP FMKPGLAEQK NAIVVPHIAS ASKWTREGMA TLAALNVLGK IKGYPVWFDA
NRVEPFLNEN ARPPAACPSI VNAKALGNTN ILYIFLIRMY NFFFLLD
//
