ID   A0A151U0Q0_CAJCA        Unreviewed;       473 AA.
AC   A0A151U0Q0;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=Pseudouridine synthase RsuA/RluA-like domain-containing protein {ECO:0000259|Pfam:PF00849};
GN   ORFNames=KK1_005458 {ECO:0000313|EMBL:KYP72855.1};
OS   Cajanus cajan (Pigeon pea) (Cajanus indicus).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC   NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Cajanus.
OX   NCBI_TaxID=3821 {ECO:0000313|EMBL:KYP72855.1, ECO:0000313|Proteomes:UP000075243};
RN   [1] {ECO:0000313|EMBL:KYP72855.1, ECO:0000313|Proteomes:UP000075243}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Asha {ECO:0000313|Proteomes:UP000075243};
RX   PubMed=22057054; DOI=10.1038/nbt.2022;
RA   Varshney R.K., Chen W., Li Y., Bharti A.K., Saxena R.K., Schlueter J.A.,
RA   Donoghue M.T., Azam S., Fan G., Whaley A.M., Farmer A.D., Sheridan J.,
RA   Iwata A., Tuteja R., Penmetsa R.V., Wu W., Upadhyaya H.D., Yang S.P.,
RA   Shah T., Saxena K.B., Michael T., McCombie W.R., Yang B., Zhang G.,
RA   Yang H., Wang J., Spillane C., Cook D.R., May G.D., Xu X., Jackson S.A.;
RT   "Draft genome sequence of pigeonpea (Cajanus cajan), an orphan legume crop
RT   of resource-poor farmers.";
RL   Nat. Biotechnol. 30:83-89(2012).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a uridine in RNA = a pseudouridine in RNA;
CC         Xref=Rhea:RHEA:48348, Rhea:RHEA-COMP:12068, Rhea:RHEA-COMP:12069,
CC         ChEBI:CHEBI:65314, ChEBI:CHEBI:65315;
CC         Evidence={ECO:0000256|ARBA:ARBA00000073};
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DR   EMBL; CM003604; KYP72855.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A151U0Q0; -.
DR   STRING; 3821.A0A151U0Q0; -.
DR   OMA; GEHHSYK; -.
DR   Proteomes; UP000075243; Chromosome 2.
DR   GO; GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0001522; P:pseudouridine synthesis; IEA:InterPro.
DR   CDD; cd02869; PseudoU_synth_RluA_like; 1.
DR   Gene3D; 3.30.2350.10; Pseudouridine synthase; 1.
DR   InterPro; IPR020103; PsdUridine_synth_cat_dom_sf.
DR   InterPro; IPR006145; PsdUridine_synth_RsuA/RluA.
DR   PANTHER; PTHR21600; MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE; 1.
DR   PANTHER; PTHR21600:SF52; RNA PSEUDOURIDINE SYNTHASE 6, CHLOROPLASTIC; 1.
DR   Pfam; PF00849; PseudoU_synth_2; 1.
DR   SUPFAM; SSF55120; Pseudouridine synthase; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000075243}.
FT   DOMAIN          216..389
FT                   /note="Pseudouridine synthase RsuA/RluA-like"
FT                   /evidence="ECO:0000259|Pfam:PF00849"
SQ   SEQUENCE   473 AA;  52718 MW;  2BCE522542CA1450 CRC64;
     MLFAGGCRSL AVPAAARALR VSRAVLSYRQ NKQAPSWCCR SSHNSYTALA DESECSTTDA
     GNLTATSSSD SFPNYDRLLP CPSHKTPPRI EHLVVTEGGP VLEHICKALD LPPLYVSDLI
     QFGAVYYALV CPQPPPNATE EQIRIFKEVT EPSVLRKRAS IKGKTVREAQ KTFRVIHVDQ
     FVEPGTYLRV HVHPKRFPRC YEIDWKSRII AVAESYVVLD KPAGTSVGGT TDNIEESCAT
     FATRALGMTT PLITTHQIDN CTEGCVVLAR TKEYCSVFHG KIREKKVKKL YLALAASPLP
     TGIISHYMRP INMAPRLISE GLLSAEFIKG WHLCRLEVIE CRKVPWPTTA VQDKYCIEDC
     GWPSQDYAYE CKINLLTGRT HQIRAQFAAC RAPLIGDSMY MPAAIADISN PGLNPFGKYK
     KDFSSESEKE TAVMNWISQH GKEPSVAIGL QACQISWDDD EHFYQAGSPW WRS
//