ID A0A151WJX1_9HYME Unreviewed; 490 AA.
AC A0A151WJX1;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial {ECO:0000256|ARBA:ARBA00020294};
DE EC=2.3.1.61 {ECO:0000256|ARBA:ARBA00012945};
DE AltName: Full=E2K {ECO:0000256|ARBA:ARBA00031331};
GN ORFNames=ALC60_12807 {ECO:0000313|EMBL:KYQ48158.1};
OS Trachymyrmex zeteki.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmicinae; Trachymyrmex.
OX NCBI_TaxID=64791 {ECO:0000313|EMBL:KYQ48158.1, ECO:0000313|Proteomes:UP000075809};
RN [1] {ECO:0000313|EMBL:KYQ48158.1, ECO:0000313|Proteomes:UP000075809}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tzet28-1 {ECO:0000313|EMBL:KYQ48158.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KYQ48158.1};
RA Nygaard S., Hu H., Boomsma J., Zhang G.;
RT "Trachymyrmex zeteki WGS genome.";
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=(R)-lipoate; Xref=ChEBI:CHEBI:83088;
CC Evidence={ECO:0000256|ARBA:ARBA00001938};
CC -!- PATHWAY: Amino-acid degradation; L-lysine degradation via saccharopine
CC pathway; glutaryl-CoA from L-lysine: step 6/6.
CC {ECO:0000256|ARBA:ARBA00005145}.
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DR EMBL; KQ983028; KYQ48158.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A151WJX1; -.
DR STRING; 64791.A0A151WJX1; -.
DR Proteomes; UP000075809; Unassembled WGS sequence.
DR GO; GO:0045252; C:oxoglutarate dehydrogenase complex; IEA:InterPro.
DR GO; GO:0004149; F:dihydrolipoyllysine-residue succinyltransferase activity; IEA:InterPro.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
DR CDD; cd06849; lipoyl_domain; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR InterPro; IPR001078; 2-oxoacid_DH_actylTfrase.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR039562; MFP_biotin_lipoyl_2.
DR InterPro; IPR011053; Single_hybrid_motif.
DR InterPro; IPR006255; SucB.
DR NCBIfam; TIGR01347; sucB; 1.
DR PANTHER; PTHR43416:SF5; DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43416; DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF00198; 2-oxoacid_dh; 1.
DR Pfam; PF13533; Biotin_lipoyl_2; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 1.
DR SUPFAM; SSF51230; Single hybrid motif; 1.
PE 4: Predicted;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Reference proteome {ECO:0000313|Proteomes:UP000075809};
KW Transferase {ECO:0000313|EMBL:KYQ48158.1}.
FT DOMAIN 126..158
FT /note="Membrane fusion protein biotin-lipoyl like"
FT /evidence="ECO:0000259|Pfam:PF13533"
FT DOMAIN 260..486
FT /note="2-oxoacid dehydrogenase acyltransferase catalytic"
FT /evidence="ECO:0000259|Pfam:PF00198"
FT REGION 164..226
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 174..225
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 490 AA; 52680 MW; 348B444C0E3764FC CRC64;
MAAMLSNCSR FAPRVITRSS VLRAEVSTMN EPFPPLSSAA ADDRHFTRPE LIQRMLAAAN
RGSVCSSRDR CVVKGALLSL FALSTPNMCL MPKLCWEIRE VVVPAFAESV SEGDVRWEKK
VGDQTSVPVP SPGPGVIKEL FFKDGDTVKP GQKLCTIDIG ATGGAAAAPG EKAPQPPAAA
PVEKAPKPVP PPPTPSAPSV APPLPRSAAP IPPPAAEPPS PQAPTASMPV AAIKHAQSLE
GAKVQLPPAD YTREIIGTRT EQRVKMNRMR LRIAERLKDA QNTNAMLTTF NEIDMSRIIE
FRKAHQESFT KKYGIKLGFM SPFVAASAYA LKDQPVVNAV IDGTDIVYRD YVDISVAVAT
PKGLVVPVLR SVENKNFAEI EIALAALGEK ARKGKITVED MDGGTFTISN GGVFGSMLGT
PIINPPQSAI LGMHGVFDRP IAVKGEVKIR PMMYIALTYD HRLIDGREAV MFLRKIKDSV
EDPRIILAGL
//
