ID A0A151WTB6_9HYME Unreviewed; 1104 AA.
AC A0A151WTB6;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Muscarinic acetylcholine receptor DM1 {ECO:0000313|EMBL:KYQ51073.1};
GN ORFNames=ALC60_09871 {ECO:0000313|EMBL:KYQ51073.1};
OS Trachymyrmex zeteki.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmicinae; Trachymyrmex.
OX NCBI_TaxID=64791 {ECO:0000313|EMBL:KYQ51073.1, ECO:0000313|Proteomes:UP000075809};
RN [1] {ECO:0000313|EMBL:KYQ51073.1, ECO:0000313|Proteomes:UP000075809}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tzet28-1 {ECO:0000313|EMBL:KYQ51073.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KYQ51073.1};
RA Nygaard S., Hu H., Boomsma J., Zhang G.;
RT "Trachymyrmex zeteki WGS genome.";
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the AHA1 family.
CC {ECO:0000256|ARBA:ARBA00006817}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000256|ARBA:ARBA00010663, ECO:0000256|RuleBase:RU000688}.
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DR EMBL; KQ982762; KYQ51073.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A151WTB6; -.
DR STRING; 64791.A0A151WTB6; -.
DR Proteomes; UP000075809; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0045202; C:synapse; IEA:GOC.
DR GO; GO:0001671; F:ATPase activator activity; IEA:InterPro.
DR GO; GO:0016907; F:G protein-coupled acetylcholine receptor activity; IEA:InterPro.
DR GO; GO:0051087; F:protein-folding chaperone binding; IEA:InterPro.
DR CDD; cd15301; 7tmA_mAChR_DM1-like; 1.
DR CDD; cd08892; SRPBCC_Aha1; 1.
DR Gene3D; 3.30.530.20; -; 1.
DR Gene3D; 3.15.10.20; Activator of Hsp90 ATPase Aha1, N-terminal domain; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 2.
DR InterPro; IPR036338; Aha1.
DR InterPro; IPR015310; AHSA1-like_N.
DR InterPro; IPR013538; ASHA1-like_C.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR000995; Musac_Ach_rcpt.
DR InterPro; IPR023393; START-like_dom_sf.
DR PANTHER; PTHR24247; 5-HYDROXYTRYPTAMINE RECEPTOR; 1.
DR PANTHER; PTHR24247:SF268; MUSCARINIC ACETYLCHOLINE RECEPTOR DM1; 1.
DR Pfam; PF00001; 7tm_1; 2.
DR Pfam; PF09229; Aha1_N; 1.
DR Pfam; PF08327; AHSA1; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR00243; MUSCARINICR.
DR SMART; SM01000; Aha1_N; 1.
DR SUPFAM; SSF103111; Activator of Hsp90 ATPase, Aha1; 1.
DR SUPFAM; SSF55961; Bet v1-like; 1.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040,
KW ECO:0000256|RuleBase:RU000688};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|RuleBase:RU000688};
KW Reference proteome {ECO:0000313|Proteomes:UP000075809};
KW Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|RuleBase:RU000688};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000688};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 545..569
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 581..607
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 619..640
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 661..686
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 706..729
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1014..1035
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1055..1078
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 561..1071
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
FT REGION 431..518
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 742..770
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 850..884
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 433..491
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 492..506
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 749..770
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1104 AA; 125683 MW; 761F1E9592D1B4E8 CRC64;
MAKWGEGDPR WIVEERPDAT NVNNWHWTEK NACVWSQEKL KEFFVNSKIE GEGVSCKITE
MEKCEGEAIV NNRKGKLIFF YEWNIVLKWI LDGESSKDIE GKINIPNLSE ENDISEIDIE
ITLKDSTDEG EKVKQFLHTK GKDAIREKLK KYVSSLKEEF AKGMILPKKD NDKEKENISN
ITSGFNIKMQ MNAAVTSTNN NKTANCKIST TTIKQNVKFQ CRAGEFYNVL SSIEMVQAFT
KNPVKLEPKK NGQFELFGGN IHGEFIEITP TKIIQKWRCK QWPSGHFSDV TIDICEKNDH
TEVNLTQSGV PVSEELSTKE NWDRYRVKLF KISLKKVQLE IREAKRIRQV GRDPAGPDLA
VQLPSIYSPP HRQASSMPCA LNREVIALHT WRNMHPSTPL PQQQFDRLAR DIELAAFDEE
SVAIMAVIDE STTTEAVDEE EEEEEEEEGV EEEEEEEGVE EEAEEEGEGE EEEEEEDEDE
EDDDEEENEG EEVEKGRDRD EKTRNSPSDM NVTPMVEIPG NDSYSISNGL DCGGEPHQYT
VWERVTIVVI AVILSLTTVV GNIMVMISFK IDKNLQTISN YFLFSLAVAD FAIGLISMPL
FTVYTVLGYW PLGSHVCDTW LALDYLASNA SVLNLLIISF DRYFSVTRPL TYRAKRTTFR
AAVMIGSAWG ISLLLWPPWI YAWPYIEGQR TVPTSSCYIQ FIETNHYITF GTAIAAFYVP
VMIMTILYWR IWKETKKRQK DLPNLQAGKQ DASKRSNSSN SANIARSKDS SAVRRTYSHV
FPCSDEVLDM EESRRQRSES STADDVSHAT HIAVSYIDKH YPQYKSHRPF SWTWLKMWCI
AWWHSGRDDE DDDEEIAGPE SSHTGAGYED TLTPLSAETP LPSTVSRCPS LSAIQATGIA
LDKTAMQHEL YKRPARSVDL RNISSDTIYT ILIKLPSNGG KFSEGTSIRM IHDESVSIHP
STVTMRRPSQ MPDIRIPLNA KNIPKTLTTG KGILNKQPNK KKKKLQEKKA DRKAAKTLSA
ILLAFIITWT PYNILVLLKS LTACSWYIPQ VLWDFVYYLC YINSTVNPMC YALGNAAFRR
TYVRILKCKW QSRNRGGTGA VDRG
//
