ID A0A151WZB3_9HYME Unreviewed; 760 AA.
AC A0A151WZB3;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Putative muscarinic acetylcholine receptor gar-2 {ECO:0000313|EMBL:KYQ53116.1};
GN ORFNames=ALC60_07846 {ECO:0000313|EMBL:KYQ53116.1};
OS Trachymyrmex zeteki.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmicinae; Trachymyrmex.
OX NCBI_TaxID=64791 {ECO:0000313|EMBL:KYQ53116.1, ECO:0000313|Proteomes:UP000075809};
RN [1] {ECO:0000313|EMBL:KYQ53116.1, ECO:0000313|Proteomes:UP000075809}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tzet28-1 {ECO:0000313|EMBL:KYQ53116.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KYQ53116.1};
RA Nygaard S., Hu H., Boomsma J., Zhang G.;
RT "Trachymyrmex zeteki WGS genome.";
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000256|ARBA:ARBA00010663, ECO:0000256|RuleBase:RU000688}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KQ982649; KYQ53116.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A151WZB3; -.
DR STRING; 64791.A0A151WZB3; -.
DR Proteomes; UP000075809; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 2.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR PANTHER; PTHR24247; 5-HYDROXYTRYPTAMINE RECEPTOR; 1.
DR PANTHER; PTHR24247:SF191; MUSCARINIC ACETYLCHOLINE RECEPTOR, B-TYPE, ISOFORM A; 1.
DR Pfam; PF00001; 7tm_1; 2.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 2.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW G-protein coupled receptor {ECO:0000256|RuleBase:RU000688};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Receptor {ECO:0000256|RuleBase:RU000688, ECO:0000313|EMBL:KYQ53116.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000075809};
KW Transducer {ECO:0000256|RuleBase:RU000688};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000688};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 1..738
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
FT REGION 221..266
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 309..363
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 380..420
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 582..675
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 221..244
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 252..266
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 309..331
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 339..363
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 380..395
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 402..419
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 582..627
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 628..675
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 760 AA; 83050 MW; 5CEBD7C758AF635F CRC64;
MLIGTVSMPF YTVYVLMGYW NLGPLLCDLW LSVDYTVCLV SQYTVLLITI DRFCSVKIAA
QYRSWRTEQR VIWMVTIIWI IPALLFFISI FGWEHFIGYR DLNPGQCAVQ FLKDPVFNTA
LIIGYYWTTL IVLFILYGGI YKTAYDMQKK SEAKQRKMQS MVALSAGAMS GMAGRAAGIG
ISKTQSTLLS QDKPKIGATS IDDSVIGMDA TTTQKMISKT DGAMAPDSSK NVSNITVTET
EKSERSSSPA FDSDEESTIG TSQQVNIRKR SSLAGLVAQS GALQVFATNG RLNGIVPIKV
ELSVPTTRKL LPTSPTRDTP KAQTLPKIQE LSLLDTDNPA EPDKSSSRTL TPEQSLKSND
ADGNLQSIIS IEVTPPAQLK RTSISNSQQN IIPPPMQFQS SPPVSDSPTT SSSTDRPRSL
IVRSHGHGTY DILTGLDGGD LRYMDESSII LPSPSYESPP SSFSCSLANP LSTAPPSPIL
GNTMTAGAST SLLQAALIRA TAQQAGTSQL APIAQSKQHL HHPPIMSNAS SQTHPPRVFI
THQTNVASQT SPINKVHTEV SVNTDRMKRQ AVTTVITTTA AMPIESSNST ERFSDQPTKA
SSNPPQNSSS SSIMPTASAA TNSQEAKSQS QKKKETSDTE QSGSRRDFVK SIGKRLKAKT
QKKDLTVGRQ KSRTENRARK AFRTISFILG AFVACWTPYH VLALVEGFCS NPPCTNEHLF
MFSYFLCYAN SPMNPFCYAL ANQQFKKTFT RILKGDLHMT
//
