ID   A0A151X059_9HYME        Unreviewed;       471 AA.
AC   A0A151X059;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=Acetylcholine receptor subunit alpha-like 2 {ECO:0000313|EMBL:KYQ53402.1};
GN   ORFNames=ALC60_07468 {ECO:0000313|EMBL:KYQ53402.1};
OS   Trachymyrmex zeteki.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC   Formicidae; Myrmicinae; Trachymyrmex.
OX   NCBI_TaxID=64791 {ECO:0000313|EMBL:KYQ53402.1, ECO:0000313|Proteomes:UP000075809};
RN   [1] {ECO:0000313|EMBL:KYQ53402.1, ECO:0000313|Proteomes:UP000075809}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tzet28-1 {ECO:0000313|EMBL:KYQ53402.1};
RC   TISSUE=Whole body {ECO:0000313|EMBL:KYQ53402.1};
RA   Nygaard S., Hu H., Boomsma J., Zhang G.;
RT   "Trachymyrmex zeteki WGS genome.";
RL   Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; KQ982630; KYQ53402.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A151X059; -.
DR   STRING; 64791.A0A151X059; -.
DR   Proteomes; UP000075809; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005230; F:extracellular ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   CDD; cd19064; LGIC_TM_nAChR; 1.
DR   Gene3D; 2.70.170.10; Neurotransmitter-gated ion-channel ligand-binding domain; 2.
DR   Gene3D; 1.20.58.390; Neurotransmitter-gated ion-channel transmembrane domain; 2.
DR   InterPro; IPR006202; Neur_chan_lig-bd.
DR   InterPro; IPR036734; Neur_chan_lig-bd_sf.
DR   InterPro; IPR006201; Neur_channel.
DR   InterPro; IPR036719; Neuro-gated_channel_TM_sf.
DR   InterPro; IPR038050; Neuro_actylchol_rec.
DR   InterPro; IPR006029; Neurotrans-gated_channel_TM.
DR   PANTHER; PTHR18945:SF430; ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-LIKE 2; 1.
DR   PANTHER; PTHR18945; NEUROTRANSMITTER GATED ION CHANNEL; 1.
DR   Pfam; PF02931; Neur_chan_LBD; 2.
DR   Pfam; PF02932; Neur_chan_memb; 1.
DR   SUPFAM; SSF90112; Neurotransmitter-gated ion-channel transmembrane pore; 1.
DR   SUPFAM; SSF63712; Nicotinic receptor ligand binding domain-like; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000313|EMBL:KYQ53402.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000075809};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           18..471
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5007591562"
FT   TRANSMEM        165..189
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        196..218
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        230..251
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        416..440
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          22..76
FT                   /note="Neurotransmitter-gated ion-channel ligand-binding"
FT                   /evidence="ECO:0000259|Pfam:PF02931"
FT   DOMAIN          102..164
FT                   /note="Neurotransmitter-gated ion-channel ligand-binding"
FT                   /evidence="ECO:0000259|Pfam:PF02931"
FT   DOMAIN          171..432
FT                   /note="Neurotransmitter-gated ion-channel transmembrane"
FT                   /evidence="ECO:0000259|Pfam:PF02932"
SQ   SEQUENCE   471 AA;  53532 MW;  D960E607C0F0EE57 CRC64;
     MISSLIILIL SVGICYSNPD AKRLYDDLLS NYNRLIRPVF NNTDTVVVKL GLRLSQLIDL
     NLKDQILTTN VWLEHHIKMF EQPLIAVAIA SQKINMTEAG LIDLKHINQN MGDKVEVGID
     LREYYPSVEW DILGVPAERH KKYYPCCLEP YPDIFFNITL RRKTLFYTVN LIIPCVSISY
     LSVLAFYLPA DSGEKIALCI NILLSQTMFF LLISEIIPST SLALPLLGKY LLFTMILVGF
     SVVITIIILN VHYRKPSTHK MAPWVRKVFI RRLPKLLLMR VPDDLLNDLA VHKMHGREKS
     KKKSKFNAAV AAAAQSSIIS SPDSARHQRI DGCNGLHRTT AHNRFLVGSL GYNGLPTVMS
     GLDESLSDVT PRKKYPFELE KALHNVMFIQ HHIQRQDEFN AEDQDWGFVA MVLDRLFLWM
     FTIASIAGTF TILCEAPALY DDTKPIDTEY SSVAQQQYLP SSQELLKSMV L
//