ID A0A151YXQ5_9BACL Unreviewed; 646 AA.
AC A0A151YXQ5;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=acetate--CoA ligase {ECO:0000256|ARBA:ARBA00013275};
DE EC=6.2.1.1 {ECO:0000256|ARBA:ARBA00013275};
GN ORFNames=AYX07_10815 {ECO:0000313|EMBL:KYQ86496.1};
OS Thermoactinomyces sp. AS95.
OC Bacteria; Bacillota; Bacilli; Bacillales; Thermoactinomycetaceae;
OC Thermoactinomyces.
OX NCBI_TaxID=1811386 {ECO:0000313|EMBL:KYQ86496.1, ECO:0000313|Proteomes:UP000076382};
RN [1] {ECO:0000313|EMBL:KYQ86496.1, ECO:0000313|Proteomes:UP000076382}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AS95 {ECO:0000313|EMBL:KYQ86496.1,
RC ECO:0000313|Proteomes:UP000076382};
RA Bezuidt O.K., Makhalanyane T.P., Pierneef R., Mohamed G.A., Kharroub K.,
RA Cowan D.A.;
RT "Draft genome sequence of Thermoactinomyces sp. AS95.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYQ86496.1}.
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DR EMBL; LSVF01000005; KYQ86496.1; -; Genomic_DNA.
DR RefSeq; WP_049720532.1; NZ_LSVF01000005.1.
DR AlphaFoldDB; A0A151YXQ5; -.
DR STRING; 1811386.AYX07_10815; -.
DR OrthoDB; 9778383at2; -.
DR Proteomes; UP000076382; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR24095; ACETYL-COENZYME A SYNTHETASE; 1.
DR PANTHER; PTHR24095:SF14; ACETYL-COENZYME A SYNTHETASE 1; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000076382}.
FT DOMAIN 31..88
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 100..473
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 532..608
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 646 AA; 73232 MW; 609404B8B25E3B65 CRC64;
MSHEPAWVPT PGQMKKTRLY QWMNRLGYQD YDAFYRDSVK NIAWFWDEAV KDMQLRWQVP
YRQVMDMSDG ILWTRWFVGG KLNISENCLD RFVDDPSSRH RIALIWEGDN GECRKYSYRD
LWLEVNRIAG GLQKLGVKPG DRVAIYLPMI AENVIAMLAV ARIGAIFIPC FSGYGADAVA
TRIQGCEAKW LITADGFYRR GKLVRMKEEA DLAADQSPSV EKVIVVRRAN RECPARDRDV
DWDRLRTDLK ALSPHPTAAD DPVMIIYTSG TTGKPKGTVH VHAGFPVKAA FDAGYMFDVG
PGDVLFWVTD MGWMMGPWMV FGALMMGSTM IVYEGTPDYP APDRLWQLVE KNGVTHLGIS
PTLIRALMKH GDQWHEKWDL SSLRVFGSTG EPWNPEPWHW LFERVGKKKV PIFNYSGGTE
ISGGILGNHF FKPIVPCGFA GPILGMDVEV FDDSGRPVRG QVGELVLRQP WVGMTRSFWQ
DDRRYEQAYW SRWPNVWLHG DWVYIDDEKN WFITGRSDDT LKIAGKRLGP AEMESVLVNH
PLVAEAATIG IPDAEKGESA VCFVVLKGEA PKGLEEELIR FVAQKMGKAL KPKRVWVVDE
LPKTRNGKIV RRVIRAAYIG EDTGDLSSLE NTETVEAIRR LAGNEK
//
