ID A0A151YYL2_9BACL Unreviewed; 196 AA.
AC A0A151YYL2;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=bis(5'-nucleosyl)-tetraphosphatase (symmetrical) {ECO:0000256|ARBA:ARBA00012506};
DE EC=3.6.1.41 {ECO:0000256|ARBA:ARBA00012506};
GN ORFNames=AYX07_06580 {ECO:0000313|EMBL:KYQ86803.1};
OS Thermoactinomyces sp. AS95.
OC Bacteria; Bacillota; Bacilli; Bacillales; Thermoactinomycetaceae;
OC Thermoactinomyces.
OX NCBI_TaxID=1811386 {ECO:0000313|EMBL:KYQ86803.1, ECO:0000313|Proteomes:UP000076382};
RN [1] {ECO:0000313|EMBL:KYQ86803.1, ECO:0000313|Proteomes:UP000076382}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AS95 {ECO:0000313|EMBL:KYQ86803.1,
RC ECO:0000313|Proteomes:UP000076382};
RA Bezuidt O.K., Makhalanyane T.P., Pierneef R., Mohamed G.A., Kharroub K.,
RA Cowan D.A.;
RT "Draft genome sequence of Thermoactinomyces sp. AS95.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + P(1),P(4)-bis(5'-adenosyl) tetraphosphate = 2 ADP + 2
CC H(+); Xref=Rhea:RHEA:24252, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:58141, ChEBI:CHEBI:456216; EC=3.6.1.41;
CC Evidence={ECO:0000256|ARBA:ARBA00001682};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYQ86803.1}.
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DR EMBL; LSVF01000004; KYQ86803.1; -; Genomic_DNA.
DR RefSeq; WP_062843140.1; NZ_LSVF01000004.1.
DR AlphaFoldDB; A0A151YYL2; -.
DR STRING; 1811386.AYX07_06580; -.
DR OrthoDB; 9782134at2; -.
DR Proteomes; UP000076382; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd00077; HDc; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR006675; HDIG_dom.
DR InterPro; IPR005249; YqeK.
DR NCBIfam; TIGR00488; bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK; 1.
DR NCBIfam; TIGR00277; HDIG; 1.
DR PANTHER; PTHR35795:SF1; BIS(5'-NUCLEOSYL)-TETRAPHOSPHATASE, SYMMETRICAL; 1.
DR PANTHER; PTHR35795; SLR1885 PROTEIN; 1.
DR Pfam; PF01966; HD; 1.
DR SMART; SM00471; HDc; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR PROSITE; PS51831; HD; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:KYQ86803.1};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Reference proteome {ECO:0000313|Proteomes:UP000076382}.
FT DOMAIN 18..132
FT /note="HD"
FT /evidence="ECO:0000259|PROSITE:PS51831"
SQ SEQUENCE 196 AA; 22775 MW; 075E7E9A1C71813E CRC64;
MNLEYLKQAT KKELPQKRWE HTLRVAETAV QLARREGVDP HKTEVAAILH DFCKFWPGEV
LTEWILQENE RQDLLLYNKE LWHGPVGAAV ARKRFGIEDE TVLNAIRYHT SGRPDMSKME
KIIFLADYIE PGRQFPGVEE VRRIAEKSLN LAVLQSLDNT IVFLIEKGRK VYPLTLDARN
HMLDQIAQKD SREESV
//
