ID   A0A154PDM5_DUFNO        Unreviewed;       207 AA.
AC   A0A154PDM5;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   SubName: Full=Protein lethal(2)essential for life {ECO:0000313|EMBL:KZC10006.1};
GN   ORFNames=WN55_01043 {ECO:0000313|EMBL:KZC10006.1};
OS   Dufourea novaeangliae (Sweat bee).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Apoidea;
OC   Anthophila; Halictidae; Rophitinae; Dufourea.
OX   NCBI_TaxID=178035 {ECO:0000313|EMBL:KZC10006.1, ECO:0000313|Proteomes:UP000076502};
RN   [1] {ECO:0000313|EMBL:KZC10006.1, ECO:0000313|Proteomes:UP000076502}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=0120121106 {ECO:0000313|EMBL:KZC10006.1};
RC   TISSUE=Whole body {ECO:0000313|EMBL:KZC10006.1};
RA   Pan H., Kapheim K.;
RT   "The genome of Dufourea novaeangliae.";
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the small heat shock protein (HSP20) family.
CC       {ECO:0000256|PIRNR:PIRNR036514, ECO:0000256|PROSITE-ProRule:PRU00285,
CC       ECO:0000256|RuleBase:RU003616}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; KQ434879; KZC10006.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A154PDM5; -.
DR   STRING; 178035.A0A154PDM5; -.
DR   EnsemblMetazoa; XM_015576331.1; XP_015431817.1; LOC107188086.
DR   Proteomes; UP000076502; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd06526; metazoan_ACD; 1.
DR   Gene3D; 2.60.40.790; -; 1.
DR   InterPro; IPR002068; A-crystallin/Hsp20_dom.
DR   InterPro; IPR001436; Alpha-crystallin/sHSP_animal.
DR   InterPro; IPR008978; HSP20-like_chaperone.
DR   PANTHER; PTHR45640:SF13; HEAT SHOCK PROTEIN 22-RELATED; 1.
DR   PANTHER; PTHR45640; HEAT SHOCK PROTEIN HSP-12.2-RELATED; 1.
DR   Pfam; PF00011; HSP20; 1.
DR   PIRSF; PIRSF036514; Sm_HSP_B1; 1.
DR   PRINTS; PR00299; ACRYSTALLIN.
DR   SUPFAM; SSF49764; HSP20-like chaperones; 1.
DR   PROSITE; PS01031; SHSP; 1.
PE   3: Inferred from homology;
KW   Metal-binding {ECO:0000256|PIRSR:PIRSR036514-1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000076502};
KW   Stress response {ECO:0000256|ARBA:ARBA00023016};
KW   Zinc {ECO:0000256|PIRSR:PIRSR036514-1}.
FT   DOMAIN          56..167
FT                   /note="SHSP"
FT                   /evidence="ECO:0000259|PROSITE:PS01031"
FT   REGION          168..207
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        168..197
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         103
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR036514-1"
FT   BINDING         105
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR036514-1"
SQ   SEQUENCE   207 AA;  23718 MW;  D90ED66B2EAC9379 CRC64;
     MCDENLDRPH SLWDQHFGTS IDPDDVLSDL DSISTDLIMY RPIVRNKRRY HPFWKSVVRK
     GRGASTVHAN KNKLEVTLDV SQLAPEEINV KVVDKNVIVE AKHDEKEDEY GWVSRQFVRK
     YIVPSQCDIS RVESRLSSDD ILTISAARKE PLNTEVLNEK VVKIQYTGNP ALTNSEEQVN
     GTPEPQKDQQ PQRGQQHQRA RKGTKST
//