ID A0A154PEC9_DUFNO Unreviewed; 987 AA.
AC A0A154PEC9;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Anoctamin {ECO:0000256|RuleBase:RU280814};
GN ORFNames=WN55_01341 {ECO:0000313|EMBL:KZC10225.1};
OS Dufourea novaeangliae (Sweat bee).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Apoidea;
OC Anthophila; Halictidae; Rophitinae; Dufourea.
OX NCBI_TaxID=178035 {ECO:0000313|EMBL:KZC10225.1, ECO:0000313|Proteomes:UP000076502};
RN [1] {ECO:0000313|EMBL:KZC10225.1, ECO:0000313|Proteomes:UP000076502}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=0120121106 {ECO:0000313|EMBL:KZC10225.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KZC10225.1};
RA Pan H., Kapheim K.;
RT "The genome of Dufourea novaeangliae.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU280814}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU280814}.
CC -!- SIMILARITY: Belongs to the anoctamin family.
CC {ECO:0000256|ARBA:ARBA00009671, ECO:0000256|RuleBase:RU280814}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU280814}.
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DR EMBL; KQ434889; KZC10225.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A154PEC9; -.
DR STRING; 178035.A0A154PEC9; -.
DR Proteomes; UP000076502; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR InterPro; IPR032394; Anoct_dimer.
DR InterPro; IPR007632; Anoctamin.
DR InterPro; IPR049452; Anoctamin_TM.
DR PANTHER; PTHR12308; ANOCTAMIN; 1.
DR PANTHER; PTHR12308:SF83; ANOCTAMIN; 1.
DR Pfam; PF16178; Anoct_dimer; 1.
DR Pfam; PF04547; Anoctamin; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU280814};
KW Reference proteome {ECO:0000313|Proteomes:UP000076502};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU280814};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU280814}.
FT TRANSMEM 352..377
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU280814"
FT TRANSMEM 509..532
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU280814"
FT TRANSMEM 552..578
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU280814"
FT TRANSMEM 598..619
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU280814"
FT TRANSMEM 729..755
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU280814"
FT TRANSMEM 876..907
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU280814"
FT DOMAIN 117..338
FT /note="Anoctamin dimerisation"
FT /evidence="ECO:0000259|Pfam:PF16178"
FT DOMAIN 341..921
FT /note="Anoctamin transmembrane"
FT /evidence="ECO:0000259|Pfam:PF04547"
SQ SEQUENCE 987 AA; 114516 MW; 19B0EDD19D94EAFF CRC64;
MEEDDEEVSI PWIQKDKSET PDASLYRSVQ SNLNAGSVQT LYQSVRNTIY DAGSMNSLNS
MHSAISMEEI RQPDNVNTLI INNEANVTIL DGSCTDLRDS RRGSRIVSNS KPAFSSYFQD
EVRTIDFVLV WDEYNTEAQR YRSTECRRVF EKNLEKEGLQ LEYEQAEPNG LHFIKIHAPR
DVLRRYAEIL KLRLPMTKDL EGRRVPENRG NTLINEVNSL FKRIMKKYYV DETIFPTMKH
NFTAVYSRDK EYLFDLDSPN FFTAATRARI VHFILDRTRF TETMDDDFAF GIERLISDRA
YVAAYPLHDG DLQSPESMRY LLYTEWASLK KCLHYQPLDY IKEYFGVKIG LYFAWLGFYT
HMLIPASVVG LLCFIYSCAT LYSNEPSEDV CNGNGTILMC PLCDHFCGYW DLKETCLHSR
ITYLFDNPST VFFSIFMSLW ATLFLELWKR YSAEITHKWD LTGLDAQEEH PRPQYLARLA
HVKKKSLNII TNTEEPKVPF WKMRLPATIL SFSVVLLLIA IAMAAVLGVV LYRMSVLTAL
SVYGHPMVTS YAILFTTATA ASINLCCIVV FNWAYVWLAE YLTEIELLRT QTEFDDSLTL
KIYLLEFVNY YASIFYIAFF KGKFVGYPGN YNRFFDYRQE ECGPGGCLME LCIQLSIIMI
GKQAMNTILE MLFPLFYKWL NTLKVHVGMK TNGERKTTAR KYLQWIKDYK LVEWGPRSLF
PEYLEMGNVL QYGFVTIFVA AFPLAPFFAL LNNVFEMRLD AKKLLIMYRR PVGQRVIDIG
IWYRILDSIS KLSVITNAFI IAFTSNFIPR LVYRITVSDN YSLEGFLDHS LSKFNTSDLK
NGTEPFSLPA HEQIDTCRYP DYREPPNSSN KYQYSIMFWH VLAARLAFVV VFENIVALVM
ILIRWCIPDM NPKLRDRIRR EAYMTNELII RQEARRACVR SADVNENTNR WSRVMRTSLS
NSEFDLEIHG SPVPASNTHS RVGPAAL
//
