ID A0A154PFW6_DUFNO Unreviewed; 623 AA.
AC A0A154PFW6;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Intersectin-1 {ECO:0000313|EMBL:KZC10712.1};
DE Flags: Fragment;
GN ORFNames=WN55_02198 {ECO:0000313|EMBL:KZC10712.1};
OS Dufourea novaeangliae (Sweat bee).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Apoidea;
OC Anthophila; Halictidae; Rophitinae; Dufourea.
OX NCBI_TaxID=178035 {ECO:0000313|EMBL:KZC10712.1, ECO:0000313|Proteomes:UP000076502};
RN [1] {ECO:0000313|EMBL:KZC10712.1, ECO:0000313|Proteomes:UP000076502}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=0120121106 {ECO:0000313|EMBL:KZC10712.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KZC10712.1};
RA Pan H., Kapheim K.;
RT "The genome of Dufourea novaeangliae.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; KQ434896; KZC10712.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A154PFW6; -.
DR STRING; 178035.A0A154PFW6; -.
DR EnsemblMetazoa; XM_015577287.1; XP_015432773.1; LOC107188897.
DR Proteomes; UP000076502; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR CDD; cd00160; RhoGEF; 1.
DR CDD; cd11840; SH3_Intersectin_5; 1.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR46006:SF9; INTERSECTIN-2 ISOFORM X1; 1.
DR PANTHER; PTHR46006; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR AT 64C, ISOFORM A; 1.
DR Pfam; PF00168; C2; 1.
DR Pfam; PF16652; PH_13; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR Pfam; PF14604; SH3_9; 1.
DR PRINTS; PR00499; P67PHOX.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00239; C2; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50004; C2; 1.
DR PROSITE; PS50010; DH_2; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000076502};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 28..87
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 103..288
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT DOMAIN 480..597
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..25
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KZC10712.1"
FT NON_TER 623
FT /evidence="ECO:0000313|EMBL:KZC10712.1"
SQ SEQUENCE 623 AA; 71093 MW; 5F5D22426CAE2FDB CRC64;
ASYVKPLTSS SNRSTPVSHG YQESPTDPNV ERVMALYPYQ AQNEDELSFE KGDVIVVTAK
DEAAWWKGEL NGLSGVFPSN YVSPMSNETT TDPMTDLDSM ERKRQEYIKE LITTEQAYIE
DMRLVHEVFE KPLIESLVLT VDEVDKIFVN WRDIIACNDN FLRTLRIRRD NSEGEIVRMI
GDILCENIPR MSAYIRFCSC QISAAVYLQR LTETVPEFVE VAHTCQQDPR TKGMPLSSFL
IKPMQRITKY PLIIGKILEH TPVVHPDRQY LQEALAKAEE FCTQVNEGVR EKENSDRLEW
LQTHVACDGL EEQLIFNSLT NSLGPRKLLH FGILHKAKSG KELVGFLTND FLLFAQPMLA
KKSFPSGQQF SFERNEHQKF KMYRKPIFLS ELFLGDSDTN GNVSSLSWGE GTENSSKILR
LRDQKKSIIL LAASPGECSL WVRRITEARK KFLENEKTRL QRQRSKQAQF GACGRILVTV
LEGFNLKATP VRRRPPQGRL RLVVVEAEDI TVPKKGKCNT FCKVSMGSQE ERTGVVSGTD
CPLWDASMQF QVKDLLEDTL CITVFDKGYY SPDEFLGRAE IRVADIMRDS KDSCGPIQKR
IRLREVETGT VVLKLDLRLF GNR
//
