ID A0A154PKQ9_DUFNO Unreviewed; 2342 AA.
AC A0A154PKQ9;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Dynein heavy chain 2, axonemal {ECO:0000313|EMBL:KZC12413.1};
GN ORFNames=WN55_03950 {ECO:0000313|EMBL:KZC12413.1};
OS Dufourea novaeangliae (Sweat bee).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Apoidea;
OC Anthophila; Halictidae; Rophitinae; Dufourea.
OX NCBI_TaxID=178035 {ECO:0000313|EMBL:KZC12413.1, ECO:0000313|Proteomes:UP000076502};
RN [1] {ECO:0000313|EMBL:KZC12413.1, ECO:0000313|Proteomes:UP000076502}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=0120121106 {ECO:0000313|EMBL:KZC12413.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:KZC12413.1};
RA Pan H., Kapheim K.;
RT "The genome of Dufourea novaeangliae.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KQ434948; KZC12413.1; -; Genomic_DNA.
DR STRING; 178035.A0A154PKQ9; -.
DR Proteomes; UP000076502; Unassembled WGS sequence.
DR GO; GO:0030286; C:dynein complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 1.10.287.2620; -; 1.
DR Gene3D; 1.10.8.710; -; 1.
DR Gene3D; 1.20.58.1120; -; 1.
DR Gene3D; 1.20.140.100; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.20.180.20; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR035699; AAA_6.
DR InterPro; IPR026983; DHC_fam.
DR InterPro; IPR042222; Dynein_2_N.
DR InterPro; IPR043157; Dynein_AAA1S.
DR InterPro; IPR013602; Dynein_heavy_linker.
DR InterPro; IPR013594; Dynein_heavy_tail.
DR InterPro; IPR042228; Dynein_linker_3.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10676:SF183; DYNEIN AXONEMAL HEAVY CHAIN 2; 1.
DR PANTHER; PTHR10676; DYNEIN HEAVY CHAIN FAMILY PROTEIN; 1.
DR Pfam; PF12774; AAA_6; 1.
DR Pfam; PF08385; DHC_N1; 1.
DR Pfam; PF08393; DHC_N2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000076502}.
FT DOMAIN 317..883
FT /note="Dynein heavy chain tail"
FT /evidence="ECO:0000259|Pfam:PF08385"
FT DOMAIN 1371..1777
FT /note="Dynein heavy chain linker"
FT /evidence="ECO:0000259|Pfam:PF08393"
FT DOMAIN 1914..2240
FT /note="Dynein heavy chain hydrolytic ATP-binding dynein
FT motor region"
FT /evidence="ECO:0000259|Pfam:PF12774"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1407..1441
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 2342 AA; 273246 MW; 36F39ACA36385872 CRC64;
MQRWKVTLKD VPAPDPHREY LDASSTDEEE RERRKTILTQ QELRPVYLDE ELEQFTRCPN
TYERQCTLCY HLKSLSFCFK VTCVKEMTTL SGITENDFMH RHEVTIREFI NTPRISVLTV
YLLHNRLNVG LGFPIVPVRE LNYFIRESQN VLHPDTFRDR ILFGSVNEKP ESHVLMVVQN
TLAPIFVPIE TWPDKESMVL EGIPNQGLLI STKSHCTRVP QPQGPFEILY NGSEQRVESF
ARGEGKRRLT SGTITWITRQ SLQLKADFYT SLDTFLCKLT DLTYKMLGLT VIYVPREGSQ
LAEQESADES SIDKELVKRL EGVVVHWTTQ IRIALMDQEQ ATPNELLCLQ DEYEFWTYRY
DNLCGLNHQL QTSTVKKITE YLSVSHSTYV RQFLALKDEI EDGVKEAKSN IEYLRSLQAP
SAELNKCTEP SEIGKHLMKI IHLFRVIWLN SPYYNSQERI ENLFGALSNQ IIILCRGFID
LTEIFEGKTR KSIQKLNECL EACENYRSVY EKIAHAHTTL THVPWDLNVD NIFSRIDIFI
GRCQDMIEVC QAMIDFARMD ETVEETRPMF SGTKGKEREW GCQKIDRLFH EALLKIRQNS
AKIFDVLEGT WHEDMFAFRS ELKDLEVIIE NLVTSAFVGM NNVQEGIEDL QGFYNYMNRE
TLKSLFDEKT NDIWRLYSDE IQQTKQEVLD EREEYPAMTP YYAGRALNLR AKGARLESTR
RMLEEAAWMP NCSMSLDIYY QHDIVMKSID DLITYLYHSW ILSVGENPRA KLDRFLMRRA
DGKTGNLECT IDPDILTLGR ESACWVHQRF PIPVHIRVIH DKWDTLRFVY ESVLAVVISY
NKVIDALSPT ERSLFRELIR QLDRKINPGL GRLTWNTEYV EAYIEDCFNE MANLQEFIDV
YKEANFEVVQ ICENICDTPM IKIKPNYTYR LQELEQDLLT TRDETINDML TKHIKMTQYI
LVIYEGFKQV IEDSLNEWRS FLHRIDTVIM EAFRQCLRGS LEMMYLALHG DESSPPSPFI
LVHVDLVDNK INFTPNLMDI ASVISGIFDN LLDPLKKVHR MVSKFRFEHT NPPFWSLYEK
DTELLNLQQK LNDEVNFCFA QMQAYLKTWE PFQEVWEINR YLYLQRYEKL RPTAESYDAD
ITRYNIVANN VHMQETVMTV HFLDVNSDRL KGAIIEECSI WQQKFLELLE KQTETMVNHV
YHYISENSRK ITKEPTDLIS MQYSLQLYER LTSEIPREEK EFPKIQEQYQ TLEKYERPLT
FDFKRKVGHI PPAWAAYLDV LTQSELMLSE KKEEFKNMLL QDAMMMKDEV TVLVAKFAVT
GPFTSDWITK DAFDWIDYVH REIDSLKRRE SQLKSQLTIF GISQSDNLEL IQLEKDLAAL
ELVWQLTNEW YEAWDRYRTD NFWRIEMEEM DNTANVLFRK LNRLNRELKE KNWEIIEHSR
MLVDKFRRTL PLITDLKNPA MRSRHWKKVK EVIDRDFDET SETFTLEAIA EMQLQNFAEQ
IADISNAATM ELAIETGLRN ISHVWQSMPI QMVPYKDRGI YKLLSIDDVL QTLDEQQVQL
SAMKATRFVE PFATEVDYWE RTLSAVGEVL EMTLIIQRGY MYMDNIFTTE DIKKQLPKES
DVYDKLTKQW KTITSRMAQK ALALPATHEP PGLLEVLNKI NDNLESMQRA LEQYLETKRH
VFPRFYFISN DDLLEILANA RKPELIQPHI KKLFENIKSL NLGKSLTGKY LANGMFSIEG
EYVEFSASVL LEGQVERWLC DVETAMRTSL RDVLRQCRTA LRKMTAKRDR WVKEWPSQPG
ITSTQIQWTA DCTRTLLHCK LLDSRRPLKK LRRRQNQALN KYSEAIRSDL SRLDRLKFKA
IVVIEIHARD VVEKMYRSNC KDVSEFEWLS QLRFYWDKDI DDCIVWQTNT HFVYGYEYLG
TSGRLVITPL TDRCYITLTT ALHLYRGGSP KGPAGTGKTE TVKDLGKALG FNVIVVNCSE
GLDYKSMGRL FSGLAQTGAW GCFDEFNRIN IEVLSVVAQQ ILSILTAISQ KMNKFVFEGT
EISLVHTCGI FITMNPGYAG RTELPDNLKS MFRPISMMVP DSGMIAEINL FGEGFENTRI
LARKVFTLYT LAQQQLSKQY HYDFGLRGIV TLTRYAGKKK RLYPNLPDDE VIILAMKDMN
IAKLTSDDLP LFLGITSDLF PDVEVPSVDY EEIIAYITKE AIKLKLQPIP LILTKVIELY
ETMSSRHSTM MVGESNTAKT VTWQILQNTK TSMKNDKKPG HNVVHVHPIN PKALSLGELY
GEYNLSTGEW HDGVISSIMR KTCSEDTPDE KWILFDGPVD ADWIENMNSV MDDNKASSMI
LW
//
